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Human MgcRacGAP Antibody

Catalog #: AF1424
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF1424
AF1424-SP
Product Details
Citations (1)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human MgcRacGAP Antibody Summary

Species Reactivity
Human
Specificity
Detects human MgcRacGAP in direct ELISAs and Western blots.
Source
Polyclonal Chicken IgY
Purification
Antigen Affinity-purified from egg yolks
Immunogen
E. coli-derived recombinant human MgcRacGAP
Met1-Lys632 (Lys518Ser)
Accession # Q9H0H5
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human MgcRacGAP

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: MgcRacGAP

McgRac GAP is functionally converted to a Rho GAP via phosphorylation. The Rho GAP activity of MgcRac GAP has been shown to play essential roles in cytokinesis (1).

References
  1. Hiroshima, Y. et al. (2003) Develop. Cell 4:549.
Long Name
Male Germ Cell Rac GTPase-activating Protein
Entrez Gene IDs
29127 (Human)
Alternate Names
GTPase activating protein; HsCYK-4; ID-GAP; KIAA1478; Male germ cell RacGap; MgcRacGAP; MgcRacGAPrac GTPase-activating protein 1; Rac GTPase activating protein 1; RACGAP1

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Citation for Human MgcRacGAP Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint.
    Authors: Huang H, Fletcher L, Beeharry N, Daniel R, Kao G, Yen TJ, Muschel RJ
    Cancer Res., 2008-05-15;68(10):3724-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC

FAQs

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