Human KIR2DL1/KIR2DS5 APC-conjugated Antibody Summary
Accession # P43626
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
Detection of KIR2DL1/KIR2DS5 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DL1/KIR2DS5 APC-conjugated Monoclonal Antibody (Catalog # FAB1844A) and Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody (Catalog # FAB2408P). Quadrant markers were set based on control antibody staining (Catalog # IC002A). View our protocol for Staining Membrane-associated Proteins.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: KIR2DL1/KIR2DS5
KIR2DL1 is one of several immunoglobulin-like receptors expressed on NK cells that bind MHC class I molecules and transmit inhibitory signals. KIR2DL1 is specific for HLA-C alleles with Asn77 and Lys80.
Product Datasheets
Citations for Human KIR2DL1/KIR2DS5 APC-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 9
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Resistance of KIR Ligand–Missing Leukocytes to NK Cells In Vivo in Patients with Acquired Aplastic Anemia
Authors: Mai Anh Thi Nguyen, Kohei Hosokawa, Takeshi Yoroidaka, Hiroyuki Maruyama, J. Luis Espinoza, Mahmoud I. Elbadry et al.
ImmunoHorizons
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NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection
J Immunol, 2016-08-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.
Authors: Marquardt N, Beziat V, Nystrom S, Hengst J, Ivarsson M, Kekalainen E, Johansson H, Mjosberg J, Westgren M, Lankisch T, Wedemeyer H, Ellis E, Ljunggren H, Michaelsson J, Bjorkstrom N
J Immunol, 2015-02-11;194(6):2467-71.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Tracking in vivo dynamics of NK cells transferred in patients undergoing stem cell transplantation.
Authors: Killig M, Friedrichs B, Meisig J, Gentilini C, Bluthgen N, Loddenkemper C, Labopin M, Basara N, Pfrepper C, Niederwieser D, Uharek L, Romagnani C
Eur J Immunol, 2014-06-30;44(9):2822-34.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
Authors: Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M
Eur J Immunol, 2012-12-12;43(2):480-7.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients.
Authors: Beziat V, Dalgard O, Asselah T, Halfon P, Bedossa P, Boudifa A, Hervier B, Theodorou I, Martinot M, Debre P, Bjorkstrom NK, Malmberg KJ, Marcellin P, Vieillard V
Eur. J. Immunol., 2011-12-16;42(2):447-57.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs.
Authors: Beziat V, Descours B, Parizot C, Debre P, Vieillard V
PLoS ONE, 2010-08-06;5(8):e11966.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components.
Authors: Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, Quezada HC, Gahrton G, Ljunggren HG, Dilber MS
Blood, 2008-01-11;111(6):3155-62.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses
Authors: Todd Bradley, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao et al.
Cell
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