Human Integrin beta 8 APC-conjugated Antibody Summary
Glu43-Arg684 (predicted)
Accession # P26012
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
View Larger
Detection of Integrin beta 8 in WM-115 Human Cell Line by Flow Cytometry. WM-115 human melanoma cell line was stained with Mouse Anti-Human Integrin beta 8 APC-conjugated Monoclonal Antibody (Catalog # FAB4775A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Integrin beta 8
Integrin beta 8 (Integrin beta 8) is a 90 kDa type I transmembrane glycoprotein of the Integrin family of adhesion molecules. It associates with Integrin alpha V to form a receptor for vitronectin, fibrin, and the latency associated peptide (LAP). Binding to LAP promotes the proteolytic release of active TGF-beta from LAP. Integrin alpha V beta 8 is required for vascular morphogenesis in the embryonic brain and yolk sac. Within the extracellular domain, human Integrin beta 8 shares 87% aa sequence identity with mouse and rat Integrin beta 8.
Product Datasheets
Citation for Human Integrin beta 8 APC-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
-
Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual alpha v beta 6/ alpha v beta 8 Integrin Ligand
Authors: Stefano Tomassi, Vincenzo Maria D’Amore, Francesco Saverio Di Leva, Andrea Vannini, Giacomo Quilici, Michael Weinmüller et al.
Journal of Medicinal Chemistry
FAQs
No product specific FAQs exist for this product, however you may
View all Antibody FAQsReviews for Human Integrin beta 8 APC-conjugated Antibody
There are currently no reviews for this product. Be the first to review Human Integrin beta 8 APC-conjugated Antibody and earn rewards!
Have you used Human Integrin beta 8 APC-conjugated Antibody?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
