Human Integrin alpha V beta 5 PE-conjugated Antibody Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of Integrin alpha V beta 5 in MCF‑7 Human Cell Line by Flow Cytometry. MCF-7 human breast cancer cell line was stained with Mouse Anti-Human Integrin aV beta 5 PE-conjugated Monoclonal Antibody (Catalog # FAB2528P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Integrin alpha V beta 5
Integrins are heterodimeric receptors comprised of an alpha and a beta subunit. Integrin alpha V (CD51) associates with several different beta subunits, but Integrin beta 5 associates exclusively with the alpha V subunit. Integrin alpha V beta 5, also known as Integrin alpha V beta S and Integrin alpha V beta 3B, is a transmembrane heterodimeric protein that functions as a receptor for Vitronectin. It is expressed on hepatoma cells, fibroblasts and carcinoma cells.
Product Datasheets
Citations for Human Integrin alpha V beta 5 PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 3
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Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3
Authors: JS Mytych, Z Pan, C Lopez-Davi, N Redinger, C Lawrence, J Ziegler, N Popescu, JA James, AD Farris
bioRxiv : the preprint server for biology, 2023-05-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Development of novel AAV serotype 6 based vectors with selective tropism for human cancer cells.
Authors: Sayroo R, Nolasco D, Yin Z, Colon-Cortes Y, Pandya M, Ling C, Aslanidi G
Gene Ther, 2015-10-08;23(1):18-25.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages
Authors: H Hall-Rober, D Agarwal, J Obst, TB Smith, J Monzón-San, E Di Daniel, C Webber, WS James, E Mead, JB Davis, SA Cowley
Alzheimers Res Ther, 2020-11-16;12(1):151.
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