Home / Integrin alpha 6/CD49f / Human Integrin  alpha 6/CD49f Antibody

Human Integrin  alpha 6/CD49f Antibody

Catalog #: MAB1350
6 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB1350
MAB1350-SP
Product Details
Citations (6)
FAQs
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Integrin  alpha 6/CD49f Antibody Summary

Species Reactivity
Human
Specificity
Detects human Integrin  alpha 6/CD49f.
Source
Monoclonal Mouse IgG2B Clone # MP4F10
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
SW1222 human colorectal carcinoma cell line
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Flow Cytometry
2.5 µg/106 cells
Human peripheral blood mononuclear cells
Immunohistochemistry
Anbazhagan, R. et al. (1995) J. Pathology 176:227.
 
Immunoprecipitation
Anbazhagan, R. et al. (1995) J. Pathology 176:227.
 
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Integrin alpha 6/CD49f

The Integrin alpha 6 subunit, also known as CD49f and VLA-6 alpha subunit, forms a heterodimer with Integrin beta 1 (CD29) or beta 4 (CD104) subunits. Integrin alpha 6 beta 1 is a receptor for laminin. Integrin alpha 6 beta 4 is also a receptor for laminin and is a structural component of hemidesmosomes in stratified epithelia.

Entrez Gene IDs
3655 (Human); 16403 (Mouse); 101925271 (Cynomolgus Monkey)
Alternate Names
CD49 antigen-like family member F; CD49f antigen; CD49f; DKFZp686J01244; FLJ18737; Integrin alpha 6; integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6; ITGA6B; Platelet gpl; VLA-6

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Citations for Human Integrin  alpha 6/CD49f Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

6 Citations: Showing 1 - 6
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  1. Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model
    Authors: Sally Dabelsteen, Emil M.H. Pallesen, Irina N. Marinova, Mathias I. Nielsen, Maria Adamopoulou, Troels B. Rømer et al.
    Developmental Cell
  2. Clinical impact of different exosomes' protein expression in pancreatic ductal carcinoma patients treated with standard first line palliative chemotherapy
    Authors: R Giampieri, F Piva, G Occhipinti, A Bittoni, A Righetti, S Pagliarett, A Murrone, F Bianchi, C Amantini, M Giulietti, G Ricci, G Principato, G Santoni, R Berardi, S Cascinu
    PLoS ONE, 2019-05-02;14(5):e0215990.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Detection
  3. PCaAnalyser: a 2D-image analysis based module for effective determination of prostate cancer progression in 3D culture.
    Authors: Hoque, Md Tamji, Windus, Louisa C, Lovitt, Carrie J, Avery, Vicky M
    PLoS ONE, 2013-11-20;8(11):e79865.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  4. Integrin alpha5beta1 facilitates cancer cell invasion through enhanced contractile forces.
    Authors: Mierke CT, Frey B, Fellner M, Herrmann M, Fabry B
    J. Cell. Sci., 2011-01-11;124(0):369-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. Corneal epithelial cell adhesion and growth on EGF-modified aminated PDMS.
    J Biomed Mater Res A, 2010-06-01;93(3):1043-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  6. Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres
    Authors: Malgorzata Czyz, Kamila Koprowska, Malgorzata Sztiller-Sikorska
    Cancer Biology & Therapy

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