Human IFN-gamma R2 Fluorescein-conjugated Antibody

Catalog #: FAB773F
1 Citation Datasheet / COA / SDS

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FAB773F

Detection of IFN‑ gamma R2 in Human Granulocytes by Flow Cytometry.

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All IFN-gamma R2 Antibodies

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Human IFN-gamma R2 Fluorescein-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human IFN-gamma R2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross‑reactivity with recombinant human IFN‑ gamma R1 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human IFN-gamma R2
Ala22-Gln247
Accession # P38484

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Fluorescein (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of IFN‑ gamma R2 in Human Granulocytes by Flow Cytometry. Human granulocytes were stained with Goat Anti-Human IFN-gamma R2 Fluorescein-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB773F, filled histogram) or isotype control antibody (Catalog # IC108F, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: IFN-gamma R2

Interferon gamma Receptor 2 (IFN-gamma R2) is a type II transmembrane protein that associates with IFN-gamma R1 to form a high affinity receptor complex for IFN-gamma. IFN‑ gamma R2 is required for signal transduction but does not bind IFN-gamma by itself.

Long Name

Interferon gamma Receptor 2

Entrez Gene IDs

3460 (Human); 15980 (Mouse)

Alternate Names

AF-1; AF-1interferon-gamma receptor beta chain precursor10IFNGT1Interferon gamma receptor accessory factor 1; IFGR2; IFN-gamma R2; IFN-gamma receptor 2; IFNgammaR2; IFN-gamma-R2; IFNGR2; IFN-gR2; IFNGT1; interferon gamma receptor 2 (interferon gamma transducer 1); interferon gamma receptor 2; interferon gamma receptor accessory factor-1; interferon gamma receptor beta chain; Interferon gamma transducer 1

Product Datasheets

Product Datasheet

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Citation for Human IFN-gamma R2 Fluorescein-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy.
Authors: Tattermusch S, Skinner JA, Chaussabel D, Banchereau J, Berry MP, McNab FW, O'Garra A, Taylor GP, Bangham CR
PLoS Pathog., 2012-01-26;8(1):e1002480.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry