Home / IFN-gamma R2 / Human IFN-gamma  R2 APC-conjugated Antibody

Human IFN-gamma  R2 APC-conjugated Antibody

Catalog #: FAB773A
7 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB773A
Detection of IFN‑ gamma R2 in Human Blood Granulocytes by Flow Cytometry.
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Citations (7)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human IFN-gamma  R2 APC-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human IFN-gamma  R2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross‑reactivity with recombinant human IFN‑ gamma  R1 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human IFN-gamma R2
Ala22-Gln247
Accession # P38484
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of IFN-? R2 antibody in Human Blood Granulocytes antibody by Flow Cytometry. View Larger

Detection of IFN‑ gamma R2 in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Goat Anti-Human IFN-gamma R2 APC-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB773A, filled histogram) or isotype control antibody (Catalog # IC108A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: IFN-gamma R2

Interferon gamma Receptor 2 (IFN-gamma R2) is a type II transmembrane protein that associates with IFN-gamma R1 to form a high affinity receptor complex for IFN-gamma. IFN‑ gamma  R2 is required for signal transduction but does not bind IFN-gamma by itself.

Long Name
Interferon gamma Receptor 2
Entrez Gene IDs
3460 (Human); 15980 (Mouse)
Alternate Names
AF-1; AF-1interferon-gamma receptor beta chain precursor10IFNGT1Interferon gamma receptor accessory factor 1; IFGR2; IFN-gamma R2; IFN-gamma receptor 2; IFNgammaR2; IFN-gamma-R2; IFNGR2; IFN-gR2; IFNGT1; interferon gamma receptor 2 (interferon gamma transducer 1); interferon gamma receptor 2; interferon gamma receptor accessory factor-1; interferon gamma receptor beta chain; Interferon gamma transducer 1

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Citations for Human IFN-gamma  R2 APC-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

7 Citations: Showing 1 - 7
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  1. Three Copies of Four Interferon Receptor Genes Underlie a Mild Type I Interferonopathy in Down Syndrome
    Authors: Xiao-Fei Kong, Lisa Worley, Darawan Rinchai, Vincent Bondet, Puthen Veettil Jithesh, Marie Goulet et al.
    Journal of Clinical Immunology
  2. Regulation of PD-L1 expression in non–small cell lung cancer by interleukin-1 beta
    Authors: Aiko Hirayama, Kentaro Tanaka, Hirono Tsutsumi, Takayuki Nakanishi, Sho Yamashita, Shun Mizusaki et al.
    Frontiers in Immunology
  3. Induction of Chemokines by Hepatitis C Virus Proteins: Synergy of the Core Protein with Interleukin-1 beta and Interferon-gamma in Liver Bystander Cells
    Authors: Sara Abouelasrar Salama, Mieke Gouwy, Alexandra De Zutter, Noëmie Pörtner, Lotte Vanbrabant, Nele Berghmans et al.
    Journal of Interferon & Cytokine Research
  4. Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling
    Authors: C Lundtoft, P Pucholt, J Imgenberg-, J Carlsson-A, ML Eloranta, AC Syvänen, G Nordmark, JK Sandling, I Kockum, T Olsson, L Rönnblom, N Hagberg
    PLoS Genet, 2020-10-26;16(10):e1009199.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. CD133+ liver cancer stem cells resist interferon-gamma-induced autophagy.
    Authors: Li J, Chen J, Zeng T, He F, Chen S, Ma S, Bi J, Zhu X, Guan X
    BMC Cancer, 2016-01-13;16(1):15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  6. Effect of amino acid substitutions in the human IFN-gammaR2 on IFN-gamma responsiveness.
    Authors: de Paus RA, Kilic SS, Van Dissel JT, van de Vosse E
    Genes Immun., 2011-01-20;12(2):136-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  7. Partial IFN-gamma R2 deficiency is due to protein misfolding and can be rescued by inhibitors of glycosylation
    Authors: Marcela Moncada-Vélez, Rubén Martinez-Barricarte, Dusan Bogunovic, Xiao-Fei Kong, Lizbeth Blancas-Galicia, Cengiz Tirpan et al.
    Blood

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