Human FPRL2/FPR3 Antibody

Catalog # Availability Size / Price Qty
MAB3896
MAB3896-SP
Product Details
Citations (3)
FAQs
Supplemental Products
Reviews (1)

Human FPRL2/FPR3 Antibody Summary

Species Reactivity
Human
Specificity
Detects human FPRL2. Stains human FPRL2 transfectants but not irrelevant transfectants.
Source
Monoclonal Mouse IgG2B Clone # 374822
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
HEK293 human embryonic kidney cell line transfected with human FPRL2
Met1-Met352
Accession # P25089
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25 µg/106 cells
NS0 mouse myeloma cell line transfected with human FPRL2
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FPRL2/FPR3

FPRL2, also known as FMLP receptor-like 2, is a 40 kDa 7TM protein that is expressed on monocytes and dendritic cells. It interacts with formyl and acetyl peptides to attract these cells to sites of infection. FPRL2 signaling also inhibits DC maturation. Human FPRL2 shares 63% and 62% amino acid sequence identity with mouse and rat FPRL2, respectively.

Long Name
Formyl Peptide Receptor-like 2
Entrez Gene IDs
2359 (Human); 14294 (Mouse)
Alternate Names
FMLP-R-II; FMLPY; formyl peptide receptor 3; Formyl peptide receptor-like 2FMLP-related receptor II; FPR3; FPRH1; FPRH1FPRH2; FPRH2; FPRL2; FPRL2FML2_HUMAN; N-formyl peptide receptor 3; RMLP-R-I

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Citations for Human FPRL2/FPR3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. Amyloid beta and its naturally occurring N-terminal variants are potent activators of human and mouse formyl peptide receptor 1
    Authors: L Busch, Z Al Taleb, YL Tsai, VTT Nguyen, Q Lu, CV Synatschke, K Endres, B Bufe
    The Journal of Biological Chemistry, 2022-10-27;0(0):102642.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  2. Intracellular formyl peptide receptor regulates na�ve CD4 T cell migration
    Authors: HY Lee, YS Jeong, M Lee, HS Kweon, YH Huh, JS Park, JE Hwang, K Kim, YS Bae
    Biochem. Biophys. Res. Commun., 2018-02-08;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis.
    Authors: Prevete N, Liotti F, Visciano C, Marone G, Melillo R, de Paulis A
    Oncogene, 2014-09-29;34(29):3826-38.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

FAQs

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Reviews for Human FPRL2/FPR3 Antibody

Average Rating: 3 (Based on 1 Review)

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Human FPRL2/FPR3 Antibody
By Anonymous on 02/08/2017
Application: Immunocytochemistry/Immunofluorescence Sample Tested: iPSC derived cells Species: Human