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Human CXCR3 PE-conjugated Antibody

Catalog #: FAB160P
30 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB160P-025
FAB160P-100
Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry.
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Product Details
Citations (30)
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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CXCR3 PE-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human CXCR3.
Source
Monoclonal Mouse IgG1 Clone # 49801
Purification
Protein A or G purified from ascites
Immunogen
NS0 mouse myeloma cell line transfected with human CXCR3
Met1-Leu368
Accession # P49682
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of CXCR3 antibody in Human Blood Lymphocytes antibody by Flow Cytometry. View Larger

Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 PE-conjugated Monoclonal Antibody (Catalog # FAB160P) and Mouse Anti-Human CD3e Alexa Fluor® 700-conjugated Monoclonal Antibody (Catalog # FAB100N). Quadrant markers were set based on control antibody staining (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CXCR3

CXCR3 is a G protein-coupled chemokine receptor that binds the alpha chemokines MIG (CXCL9), IP-10 (CXCL10), and I-TAC (CXCL11). CXCR3 is expressed on activated T cells, B cells, and NK cells.

Entrez Gene IDs
2833 (Human); 12766 (Mouse); 84475 (Rat)
Alternate Names
CD183 antigen; CD183; chemokine (C-X-C motif) receptor 3; chemokine (C-X-C) receptor 3; CKR-L2IP-10 receptor; CMKAR3; C-X-C chemokine receptor type 3; CXCR3; CXC-R3; CXCR-3; G protein-coupled receptor 9CD182; GPR9; GPR9Mig-R; Interferon-inducible protein 10 receptor; IP10 receptor; IP10-R; Mig receptor; MigR

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Citations for Human CXCR3 PE-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

30 Citations: Showing 1 - 10
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  1. Phosphorylation barcodes direct biased chemokine signaling at CXCR3
    Authors: DS Eiger, JS Smith, T Shi, TM Stepniewsk, CF Tsai, C Honeycutt, N Boldizsar, J Gardner, CD Nicora, AM Moghieb, K Kawakami, I Choi, K Zheng, A Warman, P Alagesan, NM Knape, O Huang, JD Silverman, RD Smith, A Inoue, J Selent, JM Jacobs, S Rajagopal
    bioRxiv : the preprint server for biology, 2023-03-14;0(0):.
  2. Specific alterations in NKG2D+ T lymphocytes in relapsing-remitting and progressive multiple sclerosis patients
    Authors: A Carmena Mo, Y Carpentier, F Lemaître, N Farzam-Kia, S Da Cal, JV Guimond, E Haddad, P Duquette, JM Girard, A Prat, C Larochelle, N Arbour
    Multiple sclerosis and related disorders, 2023-01-26;71(0):104542.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. TNF-alpha augments CXCL10/CXCR3 axis activity to induce Epithelial-Mesenchymal Transition in colon cancer cell
    Authors: Z Wang, X Ao, Z Shen, L Ao, X Wu, C Pu, W Guo, W Xing, M He, H Yuan, J Yu, L Li, X Xu
    International journal of biological sciences, 2021-06-26;17(11):2683-2702.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. Endothelial cell functions impaired by interferon in vitro: Insights into the molecular mechanism of thrombotic microangiopathy associated with interferon therapy
    Authors: H Jia, C Thelwell, P Dilger, C Bird, S Daniels, M Wadhwa
    Thromb. Res., 2018-02-06;163(0):105-116.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. Autosomal dominant gain of function STAT1 mutation and severe bronchiectasis
    Authors: O Breuer, H Daum, M Cohen-Cymb, S Unger, D Shoseyov, P Stepensky, B Keller, K Warnatz, E Kerem
    Respir Med, 2017-03-22;126(0):39-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  6. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
    Authors: Morandi, Fabio, Di Carlo, Emma, Ferrone, Soldano, Petretto, Andrea, Pistoia, Vito, Airoldi, Irma
    J Immunol, 2014-02-19;192(6):2634-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  7. IL-12 directs further maturation of ex vivo differentiated NK cells with improved therapeutic potential.
    Authors: Lehmann, Dorit, Spanholtz, Jan, Sturtzel, Caterina, Tordoir, Marleen, Schlechta, Bernhard, Groenewegen, Dirk, Hofer, Erhard
    PLoS ONE, 2014-01-31;9(1):e87131.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  8. Expression and functional heterogeneity of chemokine receptors CXCR4 and CXCR7 in primary patient-derived glioblastoma cells.
    Authors: Liu, Che, Pham, Kien, Luo, Defang, Reynolds, Brent A, Hothi, Parvinde, Foltz, Gregory, Harrison, Jeffrey
    PLoS ONE, 2013-03-21;8(3):e59750.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  9. Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
    Authors: Cerdeira A, Rajakumar A, Royle C, Lo A, Husain Z, Thadhani R, Sukhatme V, Karumanchi S, Kopcow H
    J Immunol, 2013-03-13;190(8):3939-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  10. Human trophectoderm apposition is regulated by interferon gamma-induced protein 10 (IP-10) during early implantation.
    Authors: Sela H, Goldman-Wohl D, Haimov-Kochman R, Greenfield C, Natanson-Yaron S, Hamani Y, Revel A, Lavy Y, Singer O, Yachimovich-Cohen N, Turetsky T, Mandelboim O, Reubinoff B, Yagel S
    Placenta, 2013-01-08;34(3):222-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  11. Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
    Authors: Badr G, Lefevre EA, Mohany M
    PLoS ONE, 2011-09-01;6(9):e23741.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  12. Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis.
    Authors: Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, Yamagami H, Watanabe K, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T
    Clin. Exp. Immunol., 2010-11-19;163(2):215-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  13. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
    Authors: Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
    J. Immunol., 2010-02-17;184(6):2886-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  14. CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
    Authors: Carbone T, Nasorri F, Pennino D
    J. Immunol., 2009-12-11;184(2):1102-10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  15. Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome.
    Authors: Yoon KC, Park CS, You IC, Choi HJ, Lee KH, Im SK, Park HY, Pflugfelder SC
    Invest. Ophthalmol. Vis. Sci., 2009-10-22;51(2):643-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  16. IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response.
    Authors: Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, Ring J, Traidl-Hoffmann C, Albanesi C, Cavani A
    J. Allergy Clin. Immunol., 2008-12-03;123(1):59-66.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  17. Endometrial NK cells are special immature cells that await pregnancy.
    Authors: Manaster I, Mizrahi S, Goldman-Wohl D, Sela HY, Stern-Ginossar N, Lankry D, Gruda R, Hurwitz A, Bdolah Y, Haimov-Kochman R, Yagel S, Mandelboim O
    J. Immunol., 2008-08-01;181(3):1869-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  18. Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals.
    Authors: Moir S, Ho J, Malaspina A, Wang W, DiPoto AC, O'Shea MA, Roby G, Kottilil S, Arthos J, Proschan MA, Chun TW, Fauci AS
    J. Exp. Med., 2008-07-14;205(8):1797-805.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  19. Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
    Authors: Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
    J. Neuroimmunol., 2008-06-09;199(1):35-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  20. CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1.
    Authors: Nonomura C, Kikuchi J, Kiyokawa N, Ozaki H, Mitsunaga K, Ando H, Kanamori A, Kannagi R, Fujimoto J, Muroi K, Furukawa Y, Nakamura M
    Cancer Res., 2008-02-01;68(3):790-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  21. Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions.
    Authors: Pokkali S, Das SD, R L
    Cytokine, 2008-01-28;41(3):307-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  22. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients.
    Authors: Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, Bombosi P, Stingl G, Petzelbauer P, Rot A, Maurer D
    J. Immunol., 2007-09-15;179(6):4272-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  23. Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10.
    Authors: Eksteen B, Miles A, Curbishley SM, Tselepis C, Grant AJ, Walker LS, Adams DH
    J. Immunol., 2006-07-01;177(1):593-603.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  24. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
    Authors: Muller A, Sonkoly E, Eulert C, Gerber PA, Kubitza R, Schirlau K, Franken-Kunkel P, Poremba C, Snyderman C, Klotz LO, Ruzicka T, Bier H, Zlotnik A, Whiteside TL, Homey B, Hoffmann TK
    Int. J. Cancer, 2006-05-01;118(9):2147-57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  25. Distinct chemokine triggers and in vivo migratory paths of fluorescein dye-labeled T Lymphocytes in acutely simian immunodeficiency virus SIVmac251-infected and uninfected macaques.
    Authors: Clay CC, Rodrigues DS, Harvey DJ, Leutenegger CM, Esser U
    J. Virol., 2005-11-01;79(21):13759-68.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  26. CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow.
    Authors: Curbishley SM, Eksteen B, Gladue RP, Lalor P, Adams DH
    Am. J. Pathol., 2005-09-01;167(3):887-99.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  27. Chemokine networks and in vivo T-lymphocyte trafficking in nonhuman primates.
    Authors: Clay CC, Rodrigues DS, Brignolo LL, Spinner A, Tarara RP, Plopper CG, Leutenegger CM, Esser U
    J. Immunol. Methods, 2004-10-01;293(1):23-42.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  28. Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
    Authors: Liu LY, Jarjour NN, Busse WW, Kelly EA
    J. Allergy Clin. Immunol., 2003-09-01;112(3):556-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  29. Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.
    Authors: Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A
    J. Leukoc. Biol., 2003-05-01;73(5):584-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  30. Disparate Regions of the Human Chemokine CXCL10 Exhibit Broad-Spectrum Antimicrobial Activity against Biodefense and Antibiotic-Resistant Bacterial Pathogens
    Authors: Matthew A. Crawford, Amanda E. Ward, Vincent Gray, Peter Bailer, Debra J. Fisher, Ewa Kubicka et al.
    ACS Infectious Diseases

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