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Human CRHBP Antibody

Catalog #: MAB2796
1 Citation 4 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
MAB2796
MAB2796-SP
Product Details
Citations (1)
FAQs
Supplemental Products
Reviews (4)
Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CRHBP Antibody Summary

Species Reactivity
Human
Specificity
Detects human CRHBP in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse CRHBP is observed.
Source
Monoclonal Mouse IgG1 Clone # 395108
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CRHBP
Tyr25-Leu322
Accession # P24387
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human CRHBP

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CRHBP

Human CRHBP is a 37 kDa secreted glycoprotein that likely serves to regulate corticotrophin releasing hormone (CRH) availability to the adrenal. In human, CRHBP complexes with CRH to form a circulating 41 kDa complex. In rodent and horse, this complex is restricted to the CNS. Human CRHBP is synthesized as a 322 amino acid (aa) precursor that contains a 24 aa signal sequence and a 298 aa mature region. The mature region contains one potential CUB domain and five intrachain disulfide bonds. Human mature CRHBP shares 87% and 84% sequence identity with mouse and equine CRHBP, respectively.

Long Name
Corticotropin Releasing Hormone Binding Protein
Entrez Gene IDs
1393 (Human)
Alternate Names
corticotropin releasing hormone binding protein; corticotropin-releasing factor-binding protein; Corticotropin-releasing hormone-binding protein; CRFBP; CRFBPcorticotropin releasing hormone-binding protein; CRF-BPCRF-binding protein; CRHBP; CRH-BP

Product Datasheets

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Citation for Human CRHBP Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Perinatal hypothalamic-pituitary-adrenal axis regulation among women with eating disorders and their infants
    Authors: A. Easter, E. Taborelli, A. Bye, P.A. Zunszain, C.M. Pariante, J. Treasure et al.
    Psychoneuroendocrinology

FAQs

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Reviews for Human CRHBP Antibody

Average Rating: 4 (Based on 4 Reviews)

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Human CRHBP Antibody
By Anonymous on 01/14/2021
Application: Microarrays Sample Tested: EDTA Plasma Species: Human
Other Human CRHBP Antibody MAB2796
Human CRHBP Antibody
By Anonymous on 02/07/2020
Application: MiAr Sample Tested: EDTA Plasma Species: Human

Antibody was printed on custom arrays and incubated with fluorescently labeled human EDTA plasma

Microarray Human CRHBP Antibody MAB2796
Human CRHBP Antibody
By Anonymous on 11/11/2018
Application: ELISA Sample Tested: Serum and Plasma Species: Human
Human CRHBP Antibody
By Anonymous on 11/07/2018
Application: Microarrays Sample Tested: EDTA Plasma Species: Human