Human CD39L2/ENTPD6 Antibody

Catalog # Availability Size / Price Qty
AF4399
AF4399-SP
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Human CD39L2/ENTPD6 Antibody Summary

Species Reactivity
Human
Specificity
Detects human CD39L2/ENTPD6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) CD39 and rhCD39L3 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human CD39L2/ENTPD6
Lys61-Ser484
Accession # O75354
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human CD39L2/ENTPD6 (Catalog # 4399-EN)
Immunoprecipitation
25 µg/mL
Conditioned cell culture medium spiked with Recombinant Human CD39L2/ENTPD6 (Catalog # 4399-EN), see our available Western blot detection antibodies

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CD39L2/ENTPD6

Ectonucleoside triphosphate diphosphohydrolase-6 (NTPDase-6) is a secreted nucleoside phosphohydrolase of the CD39 family of enzymes (1). hNTPDase6 displays a preference for the nucleoside-5’-diphosphates GDP and IDP over CDP and UDP (2). Nucleoside-5’-triphosphates are also hydrolyzed, but at much lower rates. hNTPDase6 has a broad tissue distribution, its mRNA has been detected in all human tissues tested (1).

References
  1. Chadwick, B.P. and A.M. Frischauf (1998) Genomics. 50:357.
  2. Hicks-Berger, C.A. et al. (2000) J. Biol. Chem. 275:34041.
Long Name
Ecto-Nucleoside Triphosphate Diphosphohydrolase 6
Entrez Gene IDs
955 (Human); 12497 (Mouse); 85260 (Rat)
Alternate Names
CD39 antigen-like 2; CD39L2; CD39L2NTPDase-6; CD39-like 2; dJ738P15.3; DKFZp781G2277; DKFZp781K21102; EC 3.6.1.6; ectonucleoside triphosphate diphosphohydrolase 6 (putative function); ectonucleoside triphosphate diphosphohydrolase 6 (putative); ectonucleoside triphosphate diphosphohydrolase 6; ENTPD6; FLJ36711; IL-6SAG; IL6ST2; interleukin 6 signal transducer-2; NTPD3; NTPDase 6

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