Human CD37 PE-conjugated Antibody

Catalog #: FAB4625P Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB4625P

Detection of CD37 in Human Blood Monocytes by Flow Cytometry.

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Human CD37 PE-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human CD37. Stains human CD37 transfectants but not irrelevant transfectants.

Source

Monoclonal Mouse IgG_2A Clone # 424925

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant human CD37
Accession # NP_001765

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of CD37 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CD37 PE-conjugated Monoclonal Antibody (Catalog # FAB4625P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD37

CD37, also known as TSPAN26, is a 40‑45 kDa palmitoylated tetraspanin superfamily glycoprotein that is expressed by lymphocytes and myeloid cells. CD37 directly associates with dectin-1 on macrophages and stabilizes cell surface dectin-1 expression. It also inhibits T cell activation and proliferation by limiting T cell receptor signaling. Human CD37 shares 80% aa sequence identity with mouse and rat CD37.

Entrez Gene IDs

951 (Human); 12493 (Mouse); 29185 (Rat)

Alternate Names

CD37 antigentetraspanin-26; CD37 molecule; CD37; cell differentiation antigen 37; GP52-40; leukocyte antigen CD37; MGC120234; Tetraspanin-26; TSPAN26; tspan-26; TSPAN26leukocyte surface antigen CD37