Human AGTR-2 APC-conjugated Antibody Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of AGTR‑2 in NS0 Mouse Cell Line by Flow Cytometry. NS0 mouse myeloma cell line was stained with Mouse Anti-Human AGTR-2 APC-conjugated Monoclonal Antibody (Catalog # FAB3659A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.
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Preparation and Storage
Background: AGTR-2
AGTR-2, also known as AT2, is a 7-transmembrane protein that belongs to family 1 of G protein-coupled receptors. Both AGTR-2 and AGTR-1 bind Angiotensin II and function in the control of hemodynamics. In contrast to AGTR-1, which promotes vasoconstriction and cell proliferation, AGTR-2 inhibits growth and promotes apoptosis. In addition, Angiotensin II-induced AGTR-2 signaling induces the release of nitric oxide in the heart, kidney, and brain and participates in tissue morphogenesis and repair. Human AGTR-2 shares 92% amino acid sequence identity with mouse and rat AGTR-2.
Product Datasheets
Citations for Human AGTR-2 APC-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Data supporting that adipose-derived mesenchymal stem/stromal cells express angiotensin II receptors in situ and in vitro
Authors: LV Ageeva, VY Sysoeva, PA Tyurin-Kuz, GV Sharonov, DT Dyikanov, DV Stambolsky, NI Kalinina
Data Brief, 2017-11-21;16(0):327-333.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Local angiotensin II promotes adipogenic differentiation of human adipose tissue mesenchymal stem cells through type 2 angiotensin receptor
Authors: VY Sysoeva, LV Ageeva, PA Tyurin-Kuz, GV Sharonov, DT Dyikanov, NI Kalinina, VA Tkachuk
Stem Cell Res, 2017-11-03;25(0):115-122.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
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