This technical video provides an overview of the methodologies, tools, and reagents used to generate multicellular tumor spheroids. Specifically, this video discusses the benefits of Cultrex® extracellular matrices for spheroid formation and analysis. Technical tips are provided for using colorimetric and fluorometric assays to evaluate cell proliferation and invasion of spheroids.
Madeline Lancaster, PhD, MRC Laboratory of Molecular Biology
Omer Yilmaz, PhD, Assistant Professor of Biology, MIT
Sri Devi Narasimhan, Scientific Editor, Cell
Marie Bao, Editor, Developmental Cell
