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VH 032 phenol-alkylC4-amine

Catalog #: 6909 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6909/25
VH 032 phenol-alkylC4-amine | CAS No. 2376990-26-8 | Degrader Building Blocks
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Description: VHL ligand with alkyl linker and terminal amine for onward chemistry
Alternative Names: (S,R,S)-AHPC-phenol-C4-NH2

Chemical Name: (2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-N-(2-(4-aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride

Purity: ≥95%

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Biological Activity

VH 032 phenol-alkylC4-amine is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a short alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was VH 032 phenol - linker 1

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
632.64
Formula:
C28H41N5O5S.2HCl
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2376990-26-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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