TRPV3 74a
Chemical Name: (αS)-α-[cis-3-Hydroxy-3-methyl-1-[4-(trifluoromethyl)-2-pyridinyl]cyclobutyl]-2-pyridinemethanol
Purity: ≥98%
Biological Activity
TRPV3 74a is a selective TRPV3 antagonist (KB = 0.56 μM). Displays no significant activity against a panel of other ion channels. Exhibits efficacy in animal models of neuropathic pain. Brain penetrant.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Synthesis and pharmacology of (pyridin-2-yl)methanol derivatives as novel and selective transient receptor potential vanilloid 3 antagonists.
Gomtsyan et al.
J.Med.Chem., 2016;59:4926
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for TRPV3 74a
There are currently no reviews for this product. Be the first to review TRPV3 74a and earn rewards!
Have you used TRPV3 74a?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
