Home / Adrenergic Transporter Inhibitors / Tomoxetine hydrochloride

Tomoxetine hydrochloride

Catalog #: 2011
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2011/10
2011/50
Tomoxetine hydrochloride | CAS No. 82248-59-7 | Adrenergic Transporter Inhibitors
1 Image
Description: Potent and selective noradrenalin re-uptake inhibitor
Alternative Names: Atomoxetine,LY 139603

Chemical Name: (R)-N-Methyl-γ-(2-methylphenoxy)-benzenepropanamine hydrochloride

Purity: ≥99%

Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Tomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). Displays minimal affinity for a range of other neurotransmitter receptors and transporters (Ki > 1 μM). Antidepressant.

Technical Data

M.Wt:
291.82
Formula:
C17H21NO.HCl
Solubility:
Soluble to 50 mM in water with gentle warming
Purity:
≥99%
Storage:
Store at RT
CAS No:
82248-59-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Tomoxetine hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Tomoxetine hydrochloride include:

5 Citations: Showing 1 - 5

  1. Methylphenidate and atomox. inhibit social play behavior through prefrontal and subcortical limbic mechanisms in rats.
    Authors: Achterberg Et al.
    Psychopharmacology (Berl)  2015;35:161
  2. Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti.
    Authors: Conley Et al.
    J Neurosci  2015;352:53
  3. Amphetamine decreases α2C-adrenoceptor binding of [11C]ORM-13070: a PET study in the primate brain.
    Authors: Finnema Et al.
    Toxins (Basel)  2015;18
  4. Atomoxetine reduces anticipatory responding in a 5-choice serial reaction time task for adult zebrafish.
    Authors: Parker Et al.
    Int J Neuropsychopharmacol  2014;231:2671
  5. Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective NE reuptake inhibitors atomox. and reboxetine.
    Authors: Kobayashi Et al.
    Neuropsychopharmacology  2010;35:1560

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs
Loading...

Reviews for Tomoxetine hydrochloride

There are currently no reviews for this product. Be the first to review Tomoxetine hydrochloride and earn rewards!

Have you used Tomoxetine hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.