TLQP 21
Purity: ≥95%
Biological Activity
TLQP 21 is a VGF-derived peptide; spans residues 556-576 of the precursor sequence. Protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis. Increases energy expenditure and prevents early phase diet-induced diabetes.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cell death induced by serum and potassium deprivation.
Severini et al.
J.Neurochem., 2008;104:534 -
TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity.
Bartolomucci et al.
Proc.Natl.Acad.Sci. USA, 2006;103:14584 -
VGF-derived peptide, TLQP-21, regulates food intake and body weight in Siberian hamsters.
Jethwa et al.
Endocrinol., 2007;148:4044
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Citation for TLQP 21
The citations listed below are publications that use Tocris products. Selected citations for TLQP 21 include:
1 Citation: Showing 1 - 1
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Identification of the C3a receptor (C3AR1) as the target of the VGF-derived peptide TLQP-21 in rodent cells.
Authors: Hannedouche Et al.
Front Pharmacol 2013;288:27434
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