Home / Furin Inhibitors / SSM 3 trifluoroacetate

SSM 3 trifluoroacetate

Catalog #: 5253
4 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5253/10
SSM 3 trifluoroacetate | CAS No. 2320930-10-5 | Furin Inhibitors
1 Image
Description: Potent furin inhibitor

Chemical Name: rel-N,N''-[[(1R,3S,4S,6R)-4,6-Bis[(aminoiminomethyl)amino]-1,3-cyclohexanedyil]bis(oxy-4,1-phenylene)]bisguanidine tetratrifluoroacetate salt

Purity: ≥98%

Product Details
Citations (4)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

SSM 3 trifluoroacetate is a potent furin inhibitor (EC50 = 54 nM). Blocks furin-dependent cell surface processing of anthrax protective antigen-83 in vitro.

Technical Data

M.Wt:
952.66
Formula:
C22H32N12O2.4CF3CO2H
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2320930-10-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Selective and potent furin inhibitors protect cells from anthrax without significant toxicity.
    Remacle
    Int.J.Biochem.Cell Biol., 2010;42:987

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for SSM 3 trifluoroacetate

The citations listed below are publications that use Tocris products. Selected citations for SSM 3 trifluoroacetate include:

4 Citations: Showing 1 - 4

  1. The subtilisin-like protease furin regulates hemin-induced CD63 surface expression on platelets.
    Authors: Dicenta Et al.
    Biochem.Biophys.Res.Commun.  2024;701:149629
  2. An Arginine-Rich Motif in the ORF2 capsid protein regulates the hepatitis E virus lifecycle and interactions with the host cell.
    Authors: Hervouet Et al.
    PLoS Pathog.  2022;18:e1010798
  3. Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets.
    Authors: Rui Et al.
    J Clin Invest  2021;131
  4. Furin inhibitors block SARS-CoV-2 spike protein cleavage to suppress virus production and cytopathic effects.
    Authors: Cheng Et al.
    Cell Rep.  2020;33

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for SSM 3 trifluoroacetate

There are currently no reviews for this product. Be the first to review SSM 3 trifluoroacetate and earn rewards!

Have you used SSM 3 trifluoroacetate?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.