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RuBi-Nicotine

Catalog #: 3855
1 Citation Datasheet / COA / SDS
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3855/10
RuBi-Nicotine | CAS No. 1256362-30-7 | Additional Nicotinic Receptor Agonists
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Description: Caged nicotine; rapidly excitable by visible light

Chemical Name: Bis(2,2'-bipyridine-N,N')bis(S-nicotine-N1) ruthenium(2+) dichloride

Product Details
Citations (1)
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

RuBi-Nicotine is a ruthenium-bisbipyridine-caged nicotine, excitable by irradiation with visible light. Undergoes rapid photolysis to release nicotine (< 20 ns); exhibits a high quantum yield. Induces action potential propagation in Retzius neurons of leech ganglia with no detectable toxicity at a concentration of 1 mM.

Technical Data

M.Wt:
808.81
Formula:
C40H44Cl2N8Ru
Solubility:
Soluble to 50 mM in water
Storage:
Store at -20°C
CAS No:
1256362-30-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under licence from Columbia University

Background References

  1. A caged nicotine with nanosecond range kinetics and visible light sensitivity.
    Filevich et al.
    J.Inorg.Biochem., 2010;104:1248

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Citation for RuBi-Nicotine

The citations listed below are publications that use Tocris products. Selected citations for RuBi-Nicotine include:

1 Citation: Showing 1 - 1

  1. Axonal α7* nicotinic acetylcholine receptors modulate glutamatergic signaling and synaptic vesicle organization in ventral hippocampal projections.
    Authors: Lorna W Et al.
    Front Neural Circuits  2022;16:978837

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