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RuBi-Glutamate

Catalog #: 3574
6 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3574/10
RuBi-Glutamate | CAS No. 2417096-44-5 | Glutamate Receptor Compounds
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Description: Caged glutamate; excited by visible wavelengths

Chemical Name: (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-(S)-1-aminopropane-1,3-dicarboxylic acid ruthenium(2+) complex sodium hexafluorophosphate salt

Product Details
Citations (6)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

RuBi-Glutamate is a ruthenium-bipyridine-trimethylphosphine caged glutamate that can be excited by visible wavelengths and releases glutamate after one- or two-photon excitation. Has high quantum efficiency and can be used at low concentrations, partly avoiding blockade of GABAergic transmission seen with other caged glutamate compounds. Displays high spatial resolution and generates excitatory responses in individual dendritic spines with physiological kinetics.

MNI-caged-L-glutamate (Cat. No. 1490) also available.

Technical Data

M.Wt:
970.54
Formula:
C28H32N5O4PRu.2NaPF6
Solubility:
Soluble to 20 mM in water
Storage:
Store at -20°C
CAS No:
2417096-44-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under licence from Columbia University

Product Datasheets

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Citations for RuBi-Glutamate

The citations listed below are publications that use Tocris products. Selected citations for RuBi-Glutamate include:

6 Citations: Showing 1 - 6

  1. Spike-timing-dependent plasticity rule for single, clustered and distributed dendritic spines.
    Authors: Tazerart Et al.
    Nat Commun  2020;11:4276
  2. Kilohertz frame-rate two-photon tomography.
    Authors: Kazemipour Et al.
    Nat Methods  2019;16:778
  3. Probing Single Synapses via the Photolytic Release of Neurotransmitters
    Authors: Mitchell Et al.
    Front Synaptic Neurosci  2019;11
  4. Inhibition of striatal cholinergic interneuron activity by the Kv7 opener retigabine and the nonsteroidal anti-inflammatory drug diclofenac.
    Authors: Paz Et al.
    Neuropharmacology  2018;137:309
  5. μ-Opioid Receptor-Mediated Inhibition of Intercalated Neurons and Effect on Synaptic Transmission to the Central Amygdala.
    Authors: Blaesse Et al.
    Neuroscience  2015;35:7317
  6. Ruthenium polypyridyl phototriggers: from beginnings to perspectives.
    Authors: Roberto Et al.
    Philos Trans A Math Phys Eng Sci  2013;371:20120330

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