Home / Lipase Inhibitors / RHC 80267

RHC 80267

Catalog #: 1842
4 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1842/10
1842/50
RHC 80267 | CAS No. 83654-05-1 | Lipase Inhibitors
1 Image
Description: Diacylglycerol lipase inhibitor
Alternative Names: U 57908

Chemical Name: O,O'-[1,6-Hexanediylbis(iminocarbonyl)]dioxime cyclohexanone

Purity: ≥95%

Product Details
Citations (4)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

RHC 80267 is an inhibitor of diacylglycerol lipase (IC50 values are 1.1 and 4 μM in rat cardiac myocytes and canine platelets respectively). Weakly inhibits phospholipases C and A2. Potentiates acetylcholine evoked relaxation in mesenteric arteries by the inhibition of cholinesterase activity (IC50 = 4 μM).

Technical Data

M.Wt:
394.51
Formula:
C20H34N4O4
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥95%
Storage:
Store at +4°C
CAS No:
83654-05-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for RHC 80267

The citations listed below are publications that use Tocris products. Selected citations for RHC 80267 include:

4 Citations: Showing 1 - 4

  1. Perilipin 1 moves between the fat droplet and the endoplasmic reticulum.
    Authors: Skinner Et al.
    Adipocyte  2013;2:80
  2. Associative, bidirectional changes in neural signaling utilizing NMDA receptor- and endocannabinoid-dependent mechanisms.
    Authors: Li and Burrell
    Learn Mem  2011;18:545
  3. The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis.
    Authors: Breunig Et al.
    Am J Physiol Gastrointest Liver Physiol  2010;30:8965
  4. Diacylglycerol enrichment of endoplasmic reticulum or lipid droplets recruits perilipin 3/TIP47 during lipid storage and mobilization.
    Authors: Skinner Et al.
    J Biol Chem  2009;284:30941

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for RHC 80267

There are currently no reviews for this product. Be the first to review RHC 80267 and earn rewards!

Have you used RHC 80267?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.