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Recombinant Mouse ICAM-1/CD54 Fc Chimera Protein, CF

Catalog #: 796-IC
82 Citations 1 Review Datasheet / COA / SDS
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796-IC-050
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Recombinant Mouse ICAM-1/CD54 Fc Chimera Protein, CF Summary

Product Specifications

Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells. When 5 x 104 cells/well are added to rmICAM/Fc Chimera coated plates (12.5 µg/mL with 100 µL/well), approximately 65-95% will adhere after 1 hour incubation at 37 °C.
Optimal dilutions should be determined by each laboratory for each application.
Source
Mouse myeloma cell line, NS0-derived mouse ICAM-1/CD54 protein
Mouse ICAM-1
(Gln28-Asn485)
Accession # Q3U8M7		 IEGRMD Human IgG1
(Pro100-Lys330)
N-terminus C-terminus
Accession #
Q3U8M7
N-terminal Sequence
Analysis
Gln28
Structure / Form
Disulfide-linked homodimer
Predicted Molecular Mass
76.8 kDa (monomer)
SDS-PAGE
110-130 kDa, reducing conditions

Product Datasheets

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796-IC

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

796-IC

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 0.4 mg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: ICAM-1/CD54

Intercellular Adhesion Molecule-1 (ICAM-1, CD54) binds the leukocyte integrins LFA-1 and Mac-1. ICAM-1 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1 beta and LPS. Mouse and human ICAM-1 share approximately 54% amino acid identity.

Soluble ICAM-1 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, leukocyte adhesion deficiency syndrome (LAD), cancer and transplantation.

References
  1. Pigott, R. and C. Power (1993) in The Adhesion Molecule Facts Book. Academic Press, p. 74.
  2. Siu, G. et al. (1989) J. Immunol. 143:3813.
  3. Ballantyne, C.M. et al. (1989) Nuc. Acid. Res. 17:5853.
Long Name
Intercellular Adhesion Molecule 1
Entrez Gene IDs
3383 (Human); 15894 (Mouse); 25464 (Rat)
Alternate Names
BB2; CD54 antigen; CD54; cell surface glycoprotein P3.58; human rhinovirus receptor; ICAM1; ICAM-1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule 1; Major group rhinovirus receptor; P3.58

Citations for Recombinant Mouse ICAM-1/CD54 Fc Chimera Protein, CF

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

82 Citations: Showing 1 - 10
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  1. Identification of Tensin-3 as a MALT1 substrate that controls B cell adhesion and lymphoma dissemination
    Authors: Juilland, M;Alouche, N;Ubezzi, I;Gonzalez, M;Rashid, HO;Scarpellino, L;Erdmann, T;Grau, M;Lenz, G;Luther, SA;Thome, M;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation
    Authors: Pruenster, M;Immler, R;Roth, J;Kuchler, T;Bromberger, T;Napoli, M;Nussbaumer, K;Rohwedder, I;Wackerbarth, LM;Piantoni, C;Hennis, K;Fink, D;Kallabis, S;Schroll, T;Masgrau-Alsina, S;Budke, A;Liu, W;Vestweber, D;Wahl-Schott, C;Roth, J;Meissner, F;Moser, M;Vogl, T;Hornung, V;Broz, P;Sperandio, M;
    Nature immunology
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. A dhesion analysis via a tumor vasculature-like microfluidic device identifies CD8+ T�cells with enhanced tumor homing to improve cell therapy
    Authors: CP Camargo, AK Muhuri, Y Alapan, LF Sestito, M Khosla, MP Manspeaker, AS Smith, CM Paulos, SN Thomas
    Cell Reports, 2023-02-26;42(3):112175.
    Species: Mouse
    Sample Types: Recombinant Protein
    Applications: Bioassay
  4. TGFbeta1+CCR5+ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice
    Authors: J Li, Z Yao, X Liu, R Duan, X Yi, A Ayoub, JO Sanders, A Mesfin, L Xing, BF Boyce
    Nature Communications, 2023-01-11;14(1):159.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Eph/Ephrin Promotes the Adhesion of Liver Tissue-Resident Macrophages to a Mimicked Surface of Liver Sinusoidal Endothelial Cells
    Authors: S Kohara, K Ogawa
    Biomedicines, 2022-12-12;10(12):.
    Species: Mouse
    Sample Types: Tissue Lysate
    Applications: Bioassay
  6. Immunopathology and Trypanosoma congolense parasite sequestration cause acute cerebral trypanosomiasis
    Authors: S Silva Pere, M De Niz, K Serre, M Ouarné, JE Coelho, CA Franco, LM Figueiredo
    Elife, 2022-07-05;11(0):.
    Species: Mouse
    Sample Types: Recombinant Protein
    Applications: Bioassay
  7. A humanized beta2 integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in�vivo
    Authors: L Wen, A Marki, Z Wang, M Orecchioni, J Makings, M Billitti, E Wang, SSA Suthahar, K Kim, WB Kiosses, Z Mikulski, K Ley
    Cell Reports, 2022-05-31;39(9):110876.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Myeloid Poldip2 Contributes to the Development of Pulmonary Inflammation by Regulating Neutrophil Adhesion in a Murine Model of Acute Respiratory Distress Syndrome
    Authors: Z Ou, E Dolmatova, R Mandavilli, H Qu, G Gafford, T White, A Valdivia, B Lassègue, MS Hernandes, KK Griendling
    Journal of the American Heart Association, 2022-05-10;11(10):e025181.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength
    Authors: Z Jing, MJ McCarron, ML Dustin, DR Fooksman
    Cell Reports, 2022-05-03;39(5):110763.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Humanized beta2 Integrin-Expressing Hoxb8 Cells Serve as Model to Study Integrin Activation
    Authors: T Bromberger, S Klapproth, M Sperandio, M Moser
    Cells, 2022-05-03;11(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Plasma cell dynamics in the bone marrow niche
    Authors: Z Benet, Z Jing, DR Fooksman
    Cell Reports, 2021-02-09;34(6):108733.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. LFA-1 signals to promote actin polymerization and upstream migration in T cells
    Authors: NH Roy, SHJ Kim, A Buffone, D Blumenthal, B Huang, S Agarwal, PL Schwartzbe, DA Hammer, JK Burkhardt
    J. Cell. Sci., 2020-09-09;133(17):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo
    Authors: V Azcutia, M Kelm, AC Luissint, K Boerner, S Flemming, M Quiros, G Newton, A Nusrat, FW Luscinskas, CA Parkos
    Mucosal Immunol, 2020-06-19;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Cellular locomotion using environmental topography
    Authors: A Reversat, F Gaertner, J Merrin, J Stopp, S Tasciyan, J Aguilera, I de Vries, R Hauschild, M Hons, M Piel, A Callan-Jon, R Voituriez, M Sixt
    Nature, 2020-05-13;582(7813):582-585.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  15. CrkL is required for donor T cell migration to GvHD target organs
    Authors: NH Roy, M Mammadli, JK Burkhardt, M Karimi
    Oncotarget, 2020-04-28;11(17):1505-1514.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance
    Authors: V Barbier, J Erbani, C Fiveash, JM Davies, J Tay, MR Tallack, J Lowe, JL Magnani, DR Pattabiram, AC Perkins, J Lisle, JEJ Rasko, JP Levesque, IG Winkler
    Nat Commun, 2020-04-27;11(1):2042.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Cofilin1 driven actin dynamics controls migration of thymocytes and is essential for positive selection in the thymus
    Authors: A Salz, C Gurniak, F Jönsson, W Witke
    J. Cell. Sci., 2020-03-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Developing a xenograft model of human vasculature in the mouse ear pinna
    Authors: GR Meehan, HE Scales, R Osii, M De Niz, JC Lawton, M Marti, P Garside, A Craig, JM Brewer
    Sci Rep, 2020-02-06;10(1):2058.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. Small GTPase ARF6 Is a Coincidence-Detection Code for RPH3A Polarization in Neutrophil Polarization
    Authors: C Ren, Q Yuan, X Jian, PA Randazzo, W Tang, D Wu
    J. Immunol., 2020-01-10;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. 3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival
    Authors: GS Gülcüler B, C Monzel, S Kleber, J Beaudouin, E Balta, T Kaindl, S Chen, L Gao, M Thiemann, CR Wirtz, Y Samstag, M Tanaka, A Martin-Vil
    Cell Rep, 2019-11-19;29(8):2295-2306.e6.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Binding Assay
  21. Increased lymphocyte activation and atherosclerosis in CD47-deficient mice
    Authors: D Engelberts, A Autio, RAF Verwillige, MAC Depuydt, G Newton, S Rattik, E Levinsohn, G Saggu, P Jarolim, H Wang, F Velazquez, AH Lichtman, FW Luscinskas
    Sci Rep, 2019-07-23;9(1):10608.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  22. Integrin CD11b activation drives anti-tumor innate immunity
    Authors: MC Schmid, SQ Khan, MM Kaneda, P Pathria, R Shepard, TL Louis, S Anand, G Woo, C Leem, MH Faridi, T Geraghty, A Rajagopala, S Gupta, M Ahmed, RI Vazquez-Pa, DA Cheresh, V Gupta, JA Varner
    Nat Commun, 2018-12-19;9(1):5379.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Methyltransferase Nsd2 Ensures Germinal Center Selection by Promoting Adhesive Interactions between B Cells and Follicular Dendritic Cells
    Authors: J Chen, N Li, Y Yin, N Zheng, M Min, B Lin, L Zhang, X Long, Y Zhang, Z Cai, S Zhai, J Qin, X Wang
    Cell Rep, 2018-12-18;25(12):3393-3404.e6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Linking single-cell measurements of mass, growth rate, and gene expression
    Authors: RJ Kimmerling, SM Prakadan, AJ Gupta, NL Calistri, MM Stevens, S Olcum, N Cermak, RS Drake, K Pelton, F De Smet, KL Ligon, AK Shalek, SR Manalis
    Genome Biol., 2018-11-27;19(1):207.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus
    Authors: FA Moretti, S Klapproth, R Ruppert, A Margraf, J Weber, R Pick, C Scheierman, M Sperandio, R Fässler, M Moser
    Elife, 2018-09-06;7(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive
    Authors: M Keszei, J Record, JS Kritikou, H Wurzer, C Geyer, M Thiemann, P Drescher, H Brauner, L Köcher, J James, M He, MA Baptista, CI Dahlberg, A Biswas, S Lain, DP Lane, W Song, K Pütsep, P Vandenberg, SB Snapper, LS Westerberg
    J. Clin. Invest., 2018-08-20;128(9):4115-4131.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Nanovesicles from adipose-derived mesenchymal stem cells inhibit T lymphocyte trafficking and ameliorate chronic experimental autoimmune encephalomyelitis
    Authors: A Farinazzo, S Angiari, E Turano, E Bistaffa, S Dusi, S Ruggieri, R Bonafede, R Mariotti, G Constantin, B Bonetti
    Sci Rep, 2018-05-10;8(1):7473.
    Species: Mouse
    Sample Types: Complex Sample Type
    Applications: Bioassay
  28. Plasminogen Activator Inhibitor-1 Promotes Neutrophil Infiltration and Tissue Injury on Ischemia-Reperfusion
    Authors: M Praetner, G Zuchtriege, M Holzer, B Uhl, J Schaubäche, L Mittmann, M Fabritius, R Fürst, S Zahler, D Funken, M Lerchenber, A Khandoga, S Kanse, K Lauber, F Krombach, CA Reichel
    Arterioscler. Thromb. Vasc. Biol., 2018-01-25;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  29. Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia
    Authors: S Paetau, T Rolova, L Ning, CG Gahmberg
    Front Mol Neurosci, 2017-12-22;10(0):431.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Dual Biomembrane Force Probe enables single-cell mechanical analysis of signal crosstalk between multiple molecular species
    Authors: L Ju, Y Chen, K Li, Z Yuan, B Liu, SP Jackson, C Zhu
    Sci Rep, 2017-10-27;7(1):14185.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. PDE8 controls CD4(+) T cell motility through the PDE8A-Raf-1 kinase signaling complex
    Authors: CP Basole, RK Nguyen, K Lamothe, A Vang, R Clark, GS Baillie, PM Epstein, S Brocke
    Cell. Signal., 2017-08-26;40(0):62-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells
    Authors: JG Borger, VL Morrison, A Filby, C Garcia, LM Uotila, F Simbari, SC Fagerholm, R Zamoyska
    J. Immunol., 2017-06-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Substrate-bound CCL21 and ICAM1 combined with soluble IL-6 collectively augment the expansion of antigen-specific murine CD4+ T cells
    Authors: S Adutler-Li, I Zaretsky, H Sabany, E Kartvelish, O Golani, B Geiger, N Friedman
    Blood Adv, 2017-06-15;1(15):1016-1030.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation
    Authors: BR Gittens, JV Bodkin, S Nourshargh, M Perretti, D Cooper
    J. Immunol., 2017-04-24;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Prolonged exposure to volatile anesthetic isoflurane worsens the outcome of polymicrobial abdominal sepsis
    Authors: Sophia Koutsogian
    Toxicol. Sci, 2017-04-01;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. MFG-E8-derived peptide attenuates adhesion and migration of immune cells to endothelial cells
    Authors: Y Hirano, WL Yang, M Aziz, F Zhang, B Sherry, P Wang
    J. Leukoc. Biol, 2017-01-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Glycogen storage disease type Ib neutrophils exhibit impaired cell adhesion and migration
    Authors: Janice Chou
    Biochem. Biophys. Res. Commun., 2016-11-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Aged neutrophils contribute to the first line of defense in the acute inflammatory response
    Blood, 2016-09-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  39. ADAP plays a pivotal role in CD4+ T cell activation but is only marginally involved in CD8+ T cell activation, differentiation, and immunity to pathogens
    J Leukoc Biol, 2016-09-07;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Rac GTPase Activating Protein ARHGAP25 Regulates Leukocyte Transendothelial Migration in Mice
    J Immunol, 2016-08-26;0(0):.
    Species: Mouse
    Sample Types: Whole Blood
    Applications: Bioassay
  41. Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration
    J Immunol, 2016-07-27;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Pyk2 Controls Integrin-Dependent CTL Migration through Regulation of De-Adhesion
    J Immunol, 2016-07-25;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Post-arrest stalling rather than crawling favors CD8(+) over CD4(+) T-cell migration across the blood-brain barrier under flow in vitro
    Authors: Henriette Rudolph
    Eur J Immunol, 2016-07-22;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. WNK1 kinase balances T cell adhesion versus migration in vivo
    Nat Immunol, 2016-07-11;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Opposing effects of actin signaling and LFA-1 on establishing the affinity threshold for inducing effector T-cell responses in mice
    Eur J Immunol, 2016-06-08;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Platelets Guide Leukocytes to Their Sites of Extravasation
    PLoS Biol, 2016-05-06;14(5):e1002459.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the alpha4beta1-integrin.
    Authors: Martin-Blondel G, Pignolet B, Tietz S, Yshii L, Gebauer C, Perinat T, Van Weddingen I, Blatti C, Engelhardt B, Liblau R
    Eur J Immunol, 2015-10-06;45(12):3302-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Multi-Inhibitory Effects of A2A Adenosine Receptor Signaling on Neutrophil Adhesion Under Flow.
    Authors: Yago T, Tsukamoto H, Liu Z, Wang Y, Thompson L, McEver R
    J Immunol, 2015-09-09;195(8):3880-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Blocking neutrophil integrin activation prevents ischemia-reperfusion injury.
    Authors: Yago T, Petrich B, Zhang N, Liu Z, Shao B, Ginsberg M, McEver R
    J Exp Med, 2015-07-13;212(8):1267-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse.
    Authors: Na B, Kim H, Piragyte I, Oh H, Kwon M, Akber U, Lee H, Park D, Song W, Park Z, Im S, Rho M, Hyun Y, Kim M, Jun C
    J Cell Biol, 2015-04-13;209(1):143-62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Adhesion Assay
  51. CRK proteins selectively regulate T cell migration into inflamed tissues.
    Authors: Huang, Yanping, Clarke, Fiona, Karimi, Mobin, Roy, Nathan H, Williamson, Edward K, Okumura, Mariko, Mochizuki, Kazuhiro, Chen, Emily J, Park, Tae-Ju, Debes, Gudrun F, Zhang, Yi, Curran, Tom, Kambayashi, Taku, Burkhardt, Janis K
    J Clin Invest, 2015-01-26;125(3):1019-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Mutation in the CD45 inhibitory wedge modulates integrin activation and leukocyte recruitment during inflammation.
    Authors: Germena G, Volmering S, Sohlbach C, Zarbock A
    J Immunol, 2014-12-10;194(2):728-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.
    Authors: Kovacs M, Nemeth T, Jakus Z, Sitaru C, Simon E, Futosi K, Botz B, Helyes Z, Lowell C, Mocsai A
    J Exp Med, 2014-09-15;211(10):1993-2011.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  54. CD45 ligation expands Tregs by promoting interactions with DCs.
    Authors: Camirand, Geoffrey, Wang, Ying, Lu, Yuning, Wan, Yisong Y, Lin, Yan, Deng, Songyan, Guz, Galip, Perkins, David L, Finn, Patricia, Farber, Donna L, Flavell, Richard, Shlomchik, Warren D, Lakkis, Fadi G, Rudd, Christop, Rothstein, David M
    J Clin Invest, 2014-09-09;124(10):4603-13.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Chemokine-coupled beta2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.
    Authors: Morrison A, Yarovinsky T, Young B, Moraes F, Ross T, Ceneri N, Zhang J, Zhuang Z, Sinusas A, Pardi R, Schwartz M, Simons M, Bender J
    J Exp Med, 2014-09-01;211(10):1957-68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.
    Authors: Xu, Xiaolu, Jaeger, Emily R, Wang, Xinxin, Lagler-Ferrez, Erica, Batalov, Serge, Mathis, Nancy L, Wiltshire, Tim, Walker, John R, Cooke, Michael, Sauer, Karsten, Huang, Yina H
    PLoS ONE, 2014-08-18;9(8):e105561.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Cytoskeletal regulatory gene expression and migratory properties of B-cell progenitors are affected by the ETV6-RUNX1 rearrangement.
    Authors: Palmi C, Fazio G, Savino A, Procter J, Howell L, Cazzaniga V, Vieri M, Longinotti G, Brunati I, Andre V, Della Mina P, Villa A, Greaves M, Biondi A, D'Amico G, Ford A, Cazzaniga G
    Mol Cancer Res, 2014-07-24;12(12):1796-806.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Regulation of T cell motility in vitro and in vivo by LPA and LPA2.
    Authors: Knowlden S, Capece T, Popovic M, Chapman T, Rezaee F, Kim M, Georas S
    PLoS ONE, 2014-07-08;9(7):e101655.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis.
    Authors: Gobel K, Schuhmann M, Pankratz S, Stegner D, Herrmann A, Braun A, Breuer J, Bittner S, Ruck T, Wiendl H, Kleinschnitz C, Nieswandt B, Meuth S
    Eur J Immunol, 2014-06-05;44(8):2295-305.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Integrin-mediated interactions between B cells and follicular dendritic cells influence germinal center B cell fitness.
    Authors: Wang X, Rodda L, Bannard O, Cyster J
    J Immunol, 2014-04-16;192(10):4601-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Geometrically controlled asymmetric division of CD4+ T cells studied by immunological synapse arrays.
    Authors: Jung H, Song K, Chang J, Doh J
    PLoS ONE, 2014-03-14;9(3):e91926.
    Applications: Bioassay
  62. Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL.
    Authors: Jenkins, Misty R, Stinchcombe, Jane C, Au-Yeung, Byron B, Asano, Yukako, Ritter, Alex T, Weiss, Arthur, Griffiths, Gillian
    Elife, 2014-03-04;3(0):e01310.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. alphaPIX RhoGEF supports positive selection by restraining migration and promoting arrest of thymocytes.
    Authors: Korthals M, Schilling K, Reichardt P, Mamula D, Schluter T, Steiner M, Langnase K, Thomas U, Gundelfinger E, Premont R, Tedford K, Fischer K
    J Immunol, 2014-03-03;192(7):3228-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  64. High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function.
    Authors: Foley M, Forcier T, McAndrew E, Gonzalez M, Chen H, Juelg B, Walker B, Irvine D
    PLoS ONE, 2014-02-13;9(2):e87873.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Development of central nervous system autoimmunity is impaired in the absence of Wiskott-Aldrich syndrome protein.
    Authors: Bosticardo, Marita, Musio, Silvia, Fontana, Elena, Angiari, Stefano, Draghici, Elena, Constantin, Gabriela, Poliani, Pietro L, Pedotti, Rosetta, Villa, Anna
    PLoS ONE, 2014-01-23;9(1):e86942.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via beta2 integrins (CD11/CD18).
    Authors: Weckbach L, Gola A, Winkelmann M, Jakob S, Groesser L, Borgolte J, Pogoda F, Pick R, Pruenster M, Muller-Hocker J, Deindl E, Sperandio M, Walzog B
    Blood, 2014-01-23;123(12):1887-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis.
    Authors: Dalli, Jesmond, Norling, Lucy V, Montero-Melendez, Trinidad, Federici Canova, Donata, Lashin, Hazem, Pavlov, Anton M, Sukhorukov, Gleb B, Hinds, Charles, Perretti, Mauro
    EMBO Mol Med, 2013-12-15;6(1):27-42.
    Species: Mouse
    Sample Types: Plasma
    Applications: Bioassay
  68. A circadian clock gene, Rev-erbalpha, modulates the inflammatory function of macrophages through the negative regulation of Ccl2 expression.
    Authors: Sato S, Sakurai T, Ogasawara J, Takahashi M, Izawa T, Imaizumi K, Taniguchi N, Ohno H, Kizaki T
    J Immunol, 2013-12-04;192(1):407-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  69. Mammalian diaphanous-related formin 1 regulates GSK3beta-dependent microtubule dynamics required for T cell migratory polarization.
    Authors: Dong B, Zhang S, Gao W, Su H, Chen J, Jin F, Bhargava A, Chen X, Jorgensen L, Alberts A, Zhang J, Siminovitch K
    PLoS ONE, 2013-11-18;8(11):e80500.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. PKCtheta regulates T cell motility via ezrin-radixin-moesin localization to the uropod.
    Authors: Cannon J, Asperti-Boursin F, Letendre K, Brown I, Korzekwa K, Blaine K, Oruganti S, Sperling A, Moses M
    PLoS ONE, 2013-11-08;8(11):e78940.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  71. Endothelial junctional adhesion molecule-a guides monocytes into flow-dependent predilection sites of atherosclerosis.
    Authors: Schmitt, Martin M, Megens, Remco T, Zernecke, Alma, Bidzhekov, Kiril, van den Akker, Nynke M, Rademakers, Timo, van Zandvoort, Marc A, Hackeng, Tilman M, Koenen, Rory R, Weber, Christia
    Circulation, 2013-09-24;129(1):66-76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Janus kinases 1 and 2 regulate chemokine-mediated integrin activation and naive T-cell homing.
    Authors: Perez-Rivero G, Cascio G, Soriano S, Sanz A, de Guinoa J, Rodriguez-Frade J, Gomariz R, Holgado B, Cabanas C, Carrasco Y, Stein J, Mellado M
    Eur J Immunol, 2013-05-17;43(7):1745-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation.
    Authors: Giegold O, Ogrissek N, Richter C, Schroder M, Herrero San Juan M, Pfeilschifter J, Radeke H
    J Immunol, 2013-02-27;190(7):3696-705.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. The transcription factor NFAT exhibits signal memory during serial T cell interactions with antigen-presenting cells.
    Authors: Marangoni F, Murooka T, Manzo T, Kim E, Carrizosa E, Elpek N, Mempel T
    Immunity, 2013-01-11;38(2):237-49.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin.
    Authors: Furutani Y, Kawasaki M, Matsuno H, Mitsui S, Mori K, Yoshihara Y
    J Biol Chem, 2012-09-27;287(46):39041-9.
    Applications: Surface Plasmon Resonance
  76. Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels.
    Authors: Hyun YM, Sumagin R, Sarangi PP
    J. Exp. Med., 2012-06-18;209(7):1349-62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-beta signaling.
    Authors: Verma N, Dempsey E, Long A, Davies A, Barry S, Fallon P, Volkov Y, Kelleher D
    J Biol Chem, 2012-06-15;287(32):27204-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Difference in Th1 and Th17 lymphocyte adhesion to endothelium.
    Authors: Alcaide P, Maganto-Garcia E, Newton G, Travers R, Croce KJ, Bu DX, Luscinskas FW, Lichtman AH
    J. Immunol., 2012-01-04;188(3):1421-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. IL-12 enhances CTL synapse formation and induces self-reactivity.
    Authors: Markiewicz MA, Wise EL, Buchwald ZS, Cheney EE, Hansen TH, Suri A, Cemerski S, Allen PM, Shaw AS
    J. Immunol., 2009-02-01;182(3):1351-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut.
    Authors: Park EJ, Mora JR, Carman CV, Chen J, Sasaki Y, Cheng G, von Andrian UH, Shimaoka M
    J. Clin. Invest., 2007-09-01;117(9):2526-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  81. SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration.
    Authors: Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R
    J. Leukoc. Biol., 2006-12-18;81(3):748-56.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells.
    Authors: Bate C, Kempster S, Williams A
    Neuropharmacology, 2005-11-11;50(2):229-37.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Control

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Recombinant Mouse ICAM-1/CD54 Fc Chimera Protein, CF
By Erika Rodriguez on 01/15/2020
Application: Cell Adhesion