Recombinant Human GM-CSF Protein
Recombinant Human GM-CSF Protein Summary
Product Specifications
Ala18-Glu144
Analysis
Product Datasheets
Carrier Free
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
215-GM
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. |
Reconstitution | Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
215-GM/CF
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution | Reconstitute at 100 μg/mL in PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Scientific Data
![Recombinant Human GM-CSF Protein Bioactivity Recombinant Human GM-CSF Protein Bioactivity](https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/protein/GM-CSF_215-GM_262.jpg)
Recombinant Human GM-CSF (Catalog # 215-IL) stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED50 for this effect is 6-30 pg/mL.
![Recombinant Human GM-CSF Protein SDS-PAGE Recombinant Human GM-CSF Protein SDS-PAGE](https://aeroglobalimagesuat.blob.core.windows.net/images/datasheets/protein/GM-CSF_215-GM_260.jpg)
1 μg/lane of Recombinant Human GM-CSF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa.
Reconstitution Calculator
Background: GM-CSF
GM‑CSF was initially characterized as a factor that can support the in vitro colony formation of granulocyte‑macrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM‑CSF is produced by a number of different cell types (including T cells, B cells, macrophages, mast cells, endothelial cells, fibroblasts, and adipocytes) in response to cytokine or inflammatory stimuli. On mature hematopoietic cells, GM‑CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages, and eosinophils (1, 2). GM‑CSF promotes a Th1 biased immune response, angiogenesis, allergic inflammation, and the development of autoimmunity (3‑5). It shows clinical effectiveness in ameliorating chemotherapy‑induced neutropenia, and GM‑CSF transfected tumor cells are utilized as cancer vaccines (6, 7). The 22 kDa glycosylated GM‑CSF, similar to IL‑3 and IL‑5, is a cytokine with a core of four bundled
alpha -helices (8‑12). Mature human GM‑CSF shares 63%‑70% amino acid sequence identity with canine, feline, porcine, and rat GM‑CSF and 54% with mouse GM‑CSF. GM‑CSF exerts its biological effects through a heterodimeric receptor complex composed of GM‑CSF R alpha /CD116 and the signal transducing common beta chain (CD131) which is also a component of the high‑affinity receptors for IL‑3 and IL‑5 (13, 14). In addition, GM‑CSF binds a naturally occurring soluble form of GM‑CSF R alpha (15). Human GM‑CSF is active on canine and feline cells but not on murine cells (16‑18).
- Martinez-Moczygemba, M. and D.P. Huston (2003) J. Allergy Clin. Immunol. 112:653.
- Barreda, D.R. et al. (2004) Dev. Comp. Immunol. 28:509.
- Eksioglu, E.A. et al. (2007) Exp. Hematol. 35:1163.
- Cao, Y. (2007) J. Clin. Invest. 117:2362.
- Fleetwood, A.J. et al. (2005) Crit. Rev. Immunol. 25:405.
- Heuser, M. et al. (2007) Semin. Hematol. 44:148.
- Hege, K.M. et al. (2006) Int. Rev. Immunol. 25:321.
- Kaushansky, K. et al. (1992) Biochemistry 31:1881.
- Diederichs, K. et al. (1991) Science 254:1779.
- Cantrell, M.A. et al. (1985) Proc. Natl. Acad. Sci. 82:6250.
- Lee, F. et al. (1985) Proc. Natl. Acad. Sci. 82:4360.
- Wong, G.G. et al. (1985) Science 228:810.
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- Hayashida, K. et al. (1990) Proc. Natl. Acad. Sci. 87:9655.
- Pelley, J.L. et al. (2007) Exp. Hematol. 35:1483.
- Hogge, G.S. et al. (1990) Cancer Gene Ther. 6:26.
- Sprague, W.S. et al. (2005) J. Comp. Pathol. 133:136.
- Shanafelt, A.B. et al. (1991) J. Biol. Chem. 266:13804.
Citations for Recombinant Human GM-CSF Protein
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Combination IFNbeta and membrane-stable CD40L maximize tumor dendritic cell activation and lymph node trafficking to elicit systemic T-cell immunity
Authors: H Zheng, X Yu, ML Ibrahim, D Foresman, M Xie, JO Johnson, TA Boyle, B Ruffell, BA Perez, SJ Antonia, N Ready, AN Saltos, MJ Cantwell, AA Beg
Cancer Immunology Research, 2023-04-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models
Authors: JY Li, Y Zhao, S Gong, MM Wang, X Liu, QM He, YQ Li, SY Huang, H Qiao, XR Tan, ML Ye, XH Zhu, SW He, Q Li, YL Liang, KL Chen, SW Huang, QJ Li, J Ma, N Liu
Nature Communications, 2023-02-16;14(1):865.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cancer cell-derived type I interferons instruct tumor monocyte polarization
Authors: D Kwart, J He, S Srivatsan, C Lett, J Golubov, EM Oswald, P Poon, X Ye, J Waite, AG Zaretsky, S Haxhinasto, E Au-Yeung, NT Gupta, J Chiu, C Adler, S Cherravuru, E Malahias, N Negron, K Lanza, A Coppola, M Ni, H Song, Y Wei, GS Atwal, L Macdonald, NS Oristian, W Poueymirou, V Jankovic, M Fury, I Lowy, AJ Murphy, MA Sleeman, B Wang, D Skokos
Cell Reports, 2022-12-06;41(10):111769.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neutralizing GM-CSF autoantibodies in pulmonary alveolar proteinosis, cryptococcal meningitis and severe nocardiosis
Authors: H Salvator, A Cheng, LB Rosen, PR Williamson, JE Bennett, A Kashyap, L Ding, KJ Kwon-Chung, H Namkoong, CS Zerbe, SM Holland
Respiratory Research, 2022-10-11;23(1):280.
Species: Human
Sample Types: Plasma
Applications: ELISA Development -
Impaired proteolysis of non-canonical RAS proteins drives clonal hematopoietic transformation
Authors: S Chen, RS Vedula, A Cuevas-Nav, B Lu, SJ Hogg, E Wang, S Benbarche, K Knorr, WJ Kim, RF Stanley, H Cho, C Erickson, M Singer, D Cui, S Tittley, BH Durham, TS Pavletich, E Fiala, MF Walsh, D Inoue, S Monette, J Taylor, N Rosen, F McCormick, RC Lindsley, P Castel, O Abdel-Waha
Cancer Discovery, 2022-10-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection
Authors: SP John, A Singh, J Sun, MJ Pierre, L Alsalih, C Lipsey, Z Traore, S Balcom-Luk, CJ Bradfield, J Song, TE Markowitz, M Smelkinson, M Ferrer, IDC Fraser
Cell Reports, 2022-09-15;0(0):111441.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells
Authors: YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, A Hagner, C Lau, HH Hsu, MI Ibañez-Rio, LJ Durland, DJHF Knapp, PW Zandstra
Science Advances, 2022-08-24;8(34):eabn5522.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Genetically Engineered Pigs as Efficient Salivary Gland Bioreactors for Production of Therapeutically Valuable Human Nerve Growth Factor
Authors: F Zeng, S Liao, Z Kuang, Q Zhu, H Wei, J Shi, E Zheng, Z Xu, S Huang, L Hong, T Gu, J Yang, H Yang, G Cai, S Moisyadi, J Urschitz, Z Li, Z Wu
Cells, 2022-08-02;11(15):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns
Authors: SD van Haren, GK Pedersen, A Kumar, TJ Ruckwardt, S Moin, IN Moore, M Minai, M Liu, J Pak, F Borriello, S Doss-Golli, EMS Beijnen, S Ahmed, M Helmel, P Andersen, BS Graham, H Steen, D Christense, O Levy
Nature Communications, 2022-08-02;13(1):4234.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems
Authors: IY Quiroga, AE Cruikshank, ML Bond, KSM Reed, BA Evangelist, JH Tseng, JV Ragusa, RB Meeker, H Won, S Cohen, TJ Cohen, DH Phanstiel
Journal of Neuroinflammation, 2022-04-23;19(1):99.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells
Authors: P Sekhri, DK Ledezma, A Shukla, EE Sweeney, R Fernandes
Cancers, 2022-03-11;14(6):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Synoviocytes from pigmented villonodular synovitis are less sensitive to cadmium-induced cell death than synoviocytes from rheumatoid arthritis.
Authors: H Farese, Farese H, M Noack, Noack M, P Miossec
Sci Rep, 2022-03-09;12(1):3832.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay -
Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1beta to downregulate PPARalpha and FOXO3
Authors: Y Li, Y Zhu, S Feng, Y Ishida, TP Chiu, T Saito, S Wang, DK Ann, JJ Ou
Cell Reports, 2022-01-25;38(4):110284.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Soluble PD-L1 through alternative polyadenylation works as a decoy in lung cancer immunotherapy
Authors: R Sagawa, S Sakata, B Gong, Y Seto, A Takemoto, S Takagi, H Ninomiya, N Yanagitani, M Nakao, M Mun, K Uchibori, M Nishio, Y Miyazaki, Y Shiraishi, S Ogawa, K Kataoka, N Fujita, K Takeuchi, R Katayama
JCI Insight, 2022-01-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cancer immune therapy with PD-1-dependent CD137 co-stimulation provides localized tumour killing without systemic toxicity
Authors: Y Qiao, Y Qiu, J Ding, N Luo, H Wang, X Ling, J Sun, Z Wu, Y Wang, Y Liu, F Guo, T Sun, W Shen, M Zhang, D Wu, B Chen, W Xu, X Wang
Nature Communications, 2021-11-04;12(1):6360.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A Synthetic Hydrogel, VitroGel� ORGANOID-3, Improves Immune Cell-Epithelial Interactions in a Tissue Chip Co-Culture Model of Human Gastric Organoids and Dendritic Cells
Authors: MD Cherne, B Sidar, TA Sebrell, HS Sanchez, K Heaton, FJ Kassama, MM Roe, AB Gentry, CB Chang, ST Walk, M Jutila, JN Wilking, D Bimczok
Frontiers in Pharmacology, 2021-09-06;12(0):707891.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition
Authors: D Inoue, JT Polaski, J Taylor, P Castel, S Chen, S Kobayashi, SJ Hogg, Y Hayashi, JMB Pineda, E El Marabti, C Erickson, K Knorr, M Fukumoto, H Yamazaki, A Tanaka, C Fukui, SX Lu, BH Durham, B Liu, E Wang, S Mehta, D Zakheim, R Garippa, A Penson, GL Chew, F McCormick, RK Bradley, O Abdel-Waha
Nature Genetics, 2021-04-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Validation of Induced Microglia-Like Cells (iMG Cells) for Future Studies of Brain Diseases
Authors: A Banerjee, Y Lu, K Do, T Mize, X Wu, X Chen, J Chen
Frontiers in Cellular Neuroscience, 2021-04-09;15(0):629279.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility
Authors: R Song, Y Gao, I Dozmorov, V Malladi, I Saha, MM McDaniel, S Parameswar, C Liang, C Arana, B Zhang, B Wakeland, J Zhou, MT Weirauch, LC Kottyan, EK Wakeland, C Pasare
Cell Reports, 2021-03-23;34(12):108891.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Conversion of Human Tissue-Like Inflammatory Monocytes Into Macrophages.
Authors: Bsat M, Mehta H, Rubio M, Sarfati M
Curr Protoc, 2021-03-01;1(3):e74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy
Authors: J Li, A Wuethrich, AAI Sina, HH Cheng, Y Wang, A Behren, PN Mainwaring, M Trau
Nature Communications, 2021-02-17;12(1):1087.
Species: Human
Sample Types: Reference Standard
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Inhibition of purinergic P2X receptor 7 (P2X7R) decreases granulocyte-macrophage colony-stimulating factor (GM-CSF) expression in U251 glioblastoma cells
Authors: M Drill, KL Powell, LK Kan, NC Jones, TJ O'Brien, JA Hamilton, M Monif
Sci Rep, 2020-09-09;10(1):14844.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion
Authors: B Cioni, A Zaalberg, JR van Beijnu, MHM Melis, J van Burgst, MJ Muraro, E Hooijberg, D Peters, I Hofland, Y Lubeck, J de Jong, J Sanders, J Vivié, HG van der Po, JP de Boer, AW Griffioen, W Zwart, AM Bergman
Nat Commun, 2020-09-09;11(1):4498.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Molecular and Cellular Impact of Inflammatory Extracellular Vesicles (EVs) Derived from M1 and M2 Macrophages on Neural Action Potentials
Authors: S Vakili, TM Ahooyi, SS Yarandi, M Donadoni, J Rappaport, IK Sariyer
Brain Sci, 2020-07-03;10(7):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Midkine activation of CD8+ T cells establishes a neuron-immune-cancer axis responsible for low-grade glioma growth
Authors: X Guo, Y Pan, M Xiong, S Sanapala, C Anastasaki, O Cobb, S Dahiya, DH Gutmann
Nat Commun, 2020-05-01;11(1):2177.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages
Authors: J Lubow, MC Virgilio, M Merlino, DR Collins, M Mashiba, BG Peterson, Z Lukic, MM Painter, F Gomez-Rive, V Terry, G Zimmerman, KL Collins
Elife, 2020-03-02;9(0):.
Species: Human
Sample Types: Leukocytes
Applications: Bioassay -
The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor
Authors: B ?y?y?ska-G, B Trzaskowsk, M Dutkiewicz, O Zegrocka-S, M Machci?ska, K Bocian, M Kowalewska, K Koziak
Sci Rep, 2020-02-19;10(1):2886.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Cancer-associated fibroblasts promote immunosuppression by inducing ROS-generating monocytic MDSCs in lung squamous cell carcinoma
Authors: H Xiang, CP Ramil, J Hai, C Zhang, H Wang, AA Watkins, R Afshar, P Georgiev, MA Sze, XS Song, PJ Curran, M Cheng, JR Miller, D Sun, A Loboda, Y Jia, LY Moy, A Chi, PE Brandish
Cancer Immunol Res, 2020-02-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Environmental arginine controls multinuclear giant cell metabolism and formation
Authors: JS Brunner, L Vulliard, M Hofmann, M Kieler, A Lercher, A Vogel, M Russier, JB Brüggenthi, M Kerndl, V Saferding, B Niederreit, A Junza, A Frauenstei, C Scholtysek, Y Mikami, K Klavins, G Krönke, A Bergthaler, JJ O'Shea, T Weichhart, F Meissner, JS Smolen, P Cheng, O Yanes, J Menche, PJ Murray, O Sharif, S Blüml, G Schabbauer
Nat Commun, 2020-01-22;11(1):431.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation -
In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells
Authors: JJ Montoya, MA Turnidge, DH Wai, AR Patel, DW Lee, V Gokhale, LH Hurley, RJ Arceci, C Wetmore, DO Azorsa
BMC Cancer, 2019-12-27;19(1):1251.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions
Authors: N Chiang, S Libreros, PC Norris, X de la Rosa, CN Serhan
J. Clin. Invest., 2019-12-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Activation of autophagy and IL-10 production are regulated by Jun N-terminal kinase 1 and 2 and p38 mitogen activated protein kinase signaling pathways during Talaromyces marneffei infection within dendritic cells
Authors: R Chen, G Ji, H Ren, Z Liu, S Feng, T Zhang, L Xi, X Li
Microb. Pathog., 2019-11-26;139(0):103891.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
HIV-Specific T Cells Can Be Generated against Non-escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform
Authors: S Patel, R Hanajiri, M Grant, D Saunders, S Van Pelt, M Keller, PJ Hanley, G Simon, DF Nixon, D Hardy, RB Jones, CM Bollard
Mol Ther Methods Clin Dev, 2019-10-11;16(0):11-20.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis
Authors: A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, SC Lee, JB Micol, XJ Zhang, S de Botton, V Penard-Lac, EM Stein, H Cho, RE Miles, D Inoue, TR Albrecht, TCP Somervaill, K Batta, F Amaral, F Simeoni, DP Wilks, C Cargo, AM Intlekofer, RL Levine, H Dvinge, RK Bradley, EJ Wagner, AR Krainer, O Abdel-Waha
Nature, 2019-10-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Elevated faecal 12,13-diHOME concentration in neonates at high risk for asthma is produced by gut bacteria and impedes immune tolerance
Authors: SR Levan, KA Stamnes, DL Lin, AR Panzer, E Fukui, K McCauley, KE Fujimura, M McKean, DR Ownby, EM Zoratti, HA Boushey, MD Cabana, CC Johnson, SV Lynch
Nat Microbiol, 2019-07-22;4(11):1851-1861.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
BIN1 favors the spreading of Tau via extracellular vesicles
Authors: A Crotti, HR Sait, KM McAvoy, K Estrada, A Ergun, S Szak, G Marsh, L Jandreski, M Peterson, TL Reynolds, I Dalkilic-L, A Cameron, E Cahir-McFa, RM Ransohoff
Sci Rep, 2019-07-01;9(1):9477.
Species: Human
Sample Types: Cell Lysates
Applications: Cell Culture -
TRIM5? Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation
Authors: AI Chiramel, NR Meyerson, KL McNally, RM Broeckel, VR Montoya, O Méndez-Sol, SJ Robertson, GL Sturdevant, KJ Lubick, V Nair, BH Youseff, RM Ireland, CM Bosio, K Kim, J Luban, VM Hirsch, RT Taylor, F Bouamr, SL Sawyer, SM Best
Cell Rep, 2019-06-11;27(11):3269-3283.e6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis
Authors: BD Bryson, TR Rosebrock, FG Tafesse, CY Itoh, A Nibasumba, GH Babunovic, B Corleis, C Martin, C Keegan, P Andrade, S Realegeno, D Kwon, RL Modlin, SM Fortune
Nat Commun, 2019-05-27;10(1):2329.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Potentiating Oncolytic Virus-Induced Immune-Mediated Tumor Cell Killing Using Histone Deacetylase Inhibition
Authors: VA Jennings, GB Scott, AMS Rose, KJ Scott, G Migneco, B Keller, K Reilly, O Donnelly, H Peach, D Dewar, KJ Harrington, H Pandha, A Samson, RG Vile, AA Melcher, F Errington-
Mol. Ther., 2019-04-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neutrophil GM-CSF receptor dynamics in acute lung injury
Authors: S De Alessan, GJ Ferguson, AJ Dodd, JK Juss, A Devaprasad, S Piper, O Wyatt, H Killick, DJ Corkill, ES Cohen, A Pandit, TRDJ Radstake, R Simmonds, AM Condliffe, MA Sleeman, AS Cowburn, DK Finch, ER Chilvers
J. Leukoc. Biol., 2019-04-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists
Authors: R Gramlich, E Aliahmadi, M Peiser
Int J Mol Sci, 2019-03-19;20(6):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A Novel Gastric Spheroid Co-Culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric Epithelium
Authors: TA Sebrell, M Hashimi, B Sidar, R Wilkinson, L Kirpotina, MT Quinn, Z Malkoç, PJ Taylor, JN Wilking, D Bimczok
Cell Mol Gastroenterol Hepatol, 2019-03-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells
Authors: M Kita, Y Ano, A Inoue, J Aoki
Sci Rep, 2019-02-28;9(1):3135.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Effective delivery of the anti-mycobacterial peptide NZX in mesoporous silica nanoparticles
Authors: E Tenland, A Pochert, N Krishnan, K Umashankar, S Kalsum, K Braun, I Glegola-Ma, M Lerm, BD Robertson, M Lindén, G Godaly
PLoS ONE, 2019-02-26;14(2):e0212858.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis
Authors: JC de Quaglia, AM Della Cole, TP Gardizani, GG Romagnoli, R Kaneno, LA Dias-Melic
J Immunol Res, 2019-02-06;2019(0):1529189.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning
Authors: CM Sellgren, J Gracias, B Watmuff, JD Biag, JM Thanos, PB Whittredge, T Fu, K Worringer, HE Brown, J Wang, A Kaykas, R Karmachary, CP Goold, SD Sheridan, RH Perlis
Nat. Neurosci., 2019-02-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Brucella canis induces canine CD4+ T cells multi-cytokine Th1/Th17 production via dendritic cell activation
Authors: M Pujol, C Borie, M Montoya, A Ferreira, R Vernal
Comp. Immunol. Microbiol. Infect. Dis., 2018-11-30;62(0):68-75.
Species: Canine, Human
Sample Types: Whole Cells
Applications: Bioassay -
Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells
Authors: C Kim, B Hu, RR Jadhav, J Jin, H Zhang, MM Cavanagh, RS Akondy, R Ahmed, CM Weyand, JJ Goronzy
Cell Rep, 2018-11-20;25(8):2148-2162.e5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Attenuation of CD47-SIRP? Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis
Authors: K Vaeteewoot, R Kariya, P Pothipan, S Fujikawa, C Pairojkul, S Waraasawap, K Kuwahara, C Wongkham, S Wongkham, S Okada
Transl Oncol, 2018-11-09;12(2):217-225.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CD46 activation induces distinct CXCL-10 response in monocytes and monocyte-derived dendritic cells
Authors: AS Hansen, M Biltoft, B Bundgaard, AB Bohn, BK Møller, P Höllsberg
Cytokine, 2018-07-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia
Authors: J Zhang, Z Xiang, PA Malaviarac, Y Yan, NJ Baltz, PD Emanuel, YL Liu
Cell. Signal., 2018-06-28;50(0):72-79.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Notch Signaling Facilitates In�Vitro Generation of Cross-Presenting Classical Dendritic Cells
Authors: ME Kirkling, U Cytlak, CM Lau, KL Lewis, A Resteu, A Khodadadi-, CW Siebel, H Salmon, M Merad, A Tsirigos, M Collin, V Bigley, B Reizis
Cell Rep, 2018-06-19;23(12):3658-3672.e6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Beh�et's disease
Authors: H Nakano, Y Kirino, M Takeno, K Higashitan, H Nagai, R Yoshimi, Y Yamaguchi, I Kato, I Aoki, H Nakajima
Arthritis Res. Ther., 2018-06-12;20(1):124.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells
Authors: H Chu, CM Chan, X Zhang, Y Wang, S Yuan, J Zhou, RK Au-Yeung, KH Sze, D Yang, H Shuai, Y Hou, C Li, X Zhao, VK Poon, SP Leung, ML Yeung, J Yan, G Lu, DY Jin, GF Gao, JF Chan, KY Yuen
J. Biol. Chem., 2018-06-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation
Authors: JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani
Cell Death Dis, 2018-06-04;9(6):665.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Activated dendritic cells modulate proliferation and differentiation of human myoblasts
Authors: L Ladislau, DM Portilho, T Courau, A Solares-Pé, E Negroni, J Lainé, D Klatzmann, A Bonomo, Y Allenbach, O Benveniste, I Riederer, W Savino, V Mouly, G Butler-Bro, CF Benjamim
Cell Death Dis, 2018-05-01;9(5):551.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Anisakis pegreffii impacts differentiation and function of human dendritic cells
Authors: C Napoletano, S Mattiucci, A Colantoni, F Battisti, IG Zizzari, H Rahimi, M Nuti, A Rughetti
Parasite Immunol., 2018-05-01;0(0):e12527.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human Cytomegalovirus Encodes a Novel FLT3 Receptor Ligand Necessary for Hematopoietic Cell Differentiation and Viral Reactivation
Authors: LB Crawford, JH Kim, D Collins-Mc, BJ Lee, I Landais, C Held, JA Nelson, AD Yurochko, P Caposio
MBio, 2018-04-24;9(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dysregulated heme oxygenase-1low M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons
Authors: D Kishimoto, Y Kirino, M Tamura, M Takeno, Y Kunishita, K Takase-Min, H Nakano, I Kato, K Nagahama, R Yoshimi, K Igarashi, I Aoki, H Nakajima
Arthritis Res. Ther., 2018-04-10;20(1):64.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Idelalisib impairs TREM-1 mediated neutrophil inflammatory responses
Authors: A Alflen, N Stadler, P Aranda Lop, D Teschner, M Theobald, G He beta, MP Radsak
Sci Rep, 2018-04-03;8(1):5558.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration
Authors: X de la Rosa, PC Norris, N Chiang, AR Rodriguez, BW Spur, CN Serhan
Am. J. Pathol., 2018-04-01;188(4):950-966.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages
Authors: JAT de Albuque, PP Banerjee, A Castoldi, R Ma, NB Zurro, LH Ynoue, C Arslanian, MUW Barbosa-Ca, JEM Correia-De, FG Weiler, MR Dias-da-Si, M Lazaretti-, LA Pedroza, NOS Câmara, E Mace, JS Orange, A Condino-Ne
Front Immunol, 2018-03-21;9(0):567.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Interleukin 35: Inhibitory regulator in monocyte-derived dendritic cell maturation and activation
Authors: X Chen, S Hao, Z Zhao, J Liu, Q Shao, F Wang, D Sun, Y He, W Gao, H Mao
Cytokine, 2018-03-20;108(0):43-52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Molecular transitions in early progenitors during human cord blood hematopoiesis
Authors: S Zheng, E Papalexi, A Butler, W Stephenson, R Satija
Mol. Syst. Biol., 2018-03-15;14(3):e8041.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Efficacy of intracellular immune checkpoint-silenced DC vaccine
Authors: D Wang, XF Huang, B Hong, XT Song, L Hu, M Jiang, B Zhang, H Ning, Y Li, C Xu, X Lou, B Li, Z Yu, J Hu, J Chen, F Yang, H Gao, G Ding, L Liao, L Rollins, L Jones, SY Chen, H Chen
JCI Insight, 2018-02-08;3(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Trichinella spiralis Excretory-Secretory Products Induce Tolerogenic Properties in Human Dendritic CellsviaToll-Like Receptors 2 and 4
Authors: N Ilic, A Gruden-Mov, J Cvetkovic, S Tomic, DB Vucevic, C Aranzamend, M Colic, E Pinelli, L Sofronic-M
Front Immunol, 2018-01-24;9(0):11.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells
Authors: T Kato, T Matsuda, Y Ikeda, JH Park, M Leisegang, S Yoshimura, T Hikichi, M Harada, M Zewde, S Sato, K Hasegawa, K Kiyotani, Y Nakamura
Oncotarget, 2018-01-13;9(13):11009-11019.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
EpCAM peptide-primed dendritic cell vaccination confers significant anti-tumor immunity in hepatocellular carcinoma cells
Authors: YJ Choi, SJ Park, YS Park, HS Park, KM Yang, K Heo
PLoS ONE, 2018-01-03;13(1):e0190638.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREB-dependent signaling pathways
Authors: HD Chae, N Cox, GV Dahl, NJ Lacayo, KL Davis, S Capolicchi, M Smith, KM Sakamoto
Oncotarget, 2017-12-31;9(4):4301-4317.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Phase I clinical trial of a novel autologous modified-DC vaccine in patients with resected NSCLC
Authors: C Ge, R Li, H Song, T Geng, J Yang, Q Tan, L Song, Y Wang, Y Xue, Z Li, S Dong, Z Zhang, N Zhang, J Guo, L Hua, S Chen, X Song
BMC Cancer, 2017-12-21;17(1):884.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
An Activating Janus Kinase-3 Mutation Is Associated with Cytotoxic T Lymphocyte Antigen-4-Dependent Immune Dysregulation Syndrome
Authors: H Sic, M Speletas, V Cornacchio, M Seidl, M Beibel, B Linghu, F Yang, E Sevdali, AE Germenis, EJ Oakeley, E Vangreveli, AW Sailer, E Traggiai, H Gram, H Eibel
Front Immunol, 2017-12-15;8(0):1824.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression
Authors: MS Gresnigt, M Jaeger, RK Subbarao M, O Rasid, G Jouvion, C Fitting, WJG Melchers, TD Kanneganti, A Carvalho, O Ibrahim-Gr, FL van de Vee
Front Immunol, 2017-12-13;8(0):1777.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant
Authors: P Thornton, J Sevalle, MJ Deery, G Fraser, Y Zhou, S Ståhl, EH Franssen, RB Dodd, S Qamar, B Gomez Pere, LS Nicol, S Eketjäll, J Revell, C Jones, A Billinton, PH St George-, I Chessell, DC Crowther
EMBO Mol Med, 2017-10-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Fibromyalgia and microglial TNF-?: Translational research using human blood induced microglia-like cells
Authors: M Ohgidani, TA Kato, M Hosoi, M Tsuda, K Hayakawa, C Hayaki, R Iwaki, N Sagata, R Hashimoto, K Inoue, N Sudo, S Kanba
Sci Rep, 2017-09-19;7(1):11882.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Soluble HLA-associated peptide from PSF1 has a cancer vaccine potency
Authors: M Yoshida, Y Ishioka, T Ozawa, H Okuyama, M Iguchi, T Ota, T Ito, M Nagira, A Morita, H Tanaka, H Naito, H Kidoya, N Takakura
Sci Rep, 2017-09-11;7(1):11137.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neutrophil Fc?RIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases
Authors: H Nishi, K Furuhashi, X Cullere, G Saggu, MJ Miller, Y Chen, F Rosetti, SL Hamilton, L Yang, SP Pittman, J Liao, JM Herter, JC Berry, DJ DeAngelo, C Zhu, GC Tsokos, TN Mayadas
J. Clin. Invest., 2017-09-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXorf48 is a potential therapeutic target for achieving treatment-free remission in CML patients
Authors: M Matsushita, K Ozawa, T Suzuki, M Nakamura, N Nakano, S Kanchi, D Ichikawa, E Matsuki, M Sakurai, D Karigane, H Kasahara, N Tsukamoto, T Shimizu, T Mori, H Nakajima, S Okamoto, Y Kawakami, Y Hattori
Blood Cancer J, 2017-09-01;7(9):e601.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis
Authors: L Butcher, M Ahluwalia, T Örd, J Johnston, RH Morris, E Kiss-Toth, T Örd, JD Erusalimsk
Sci Rep, 2017-07-27;7(1):6684.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dendritic Cell Lineage Potential in Human Early Hematopoietic Progenitors
Authors: J Helft, F Anjos-Afon, AG van der Ve, P Chakravart, D Bonnet, C Reis E Sou
Cell Rep, 2017-07-18;20(3):529-537.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Prevalence and correlation of cytokine-specific autoantibodies with epidemiological factors and C-reactive protein in 8,972 healthy individuals: Results from the Danish Blood Donor Study
Authors: JH von Steman, AS Rigas, LW Thørner, DGK Rasmussen, OB Pedersen, K Rostgaard, C Erikstrup, H Ullum, MB Hansen
PLoS ONE, 2017-06-30;12(6):e0179981.
Species: Human
Sample Types: Plasma
Applications: Control -
Activation of Human Basophils by A549 Lung Epithelial Cells Reveals a Novel IgE-Dependent Response Independent of Allergen
Authors: JT Schroeder, AP Bieneman
J. Immunol., 2017-06-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human hantavirus infection elicits pronounced redistribution of mononuclear phagocytes in peripheral blood and airways
Authors: S Scholz, F Baharom, G Rankin, KT Maleki, S Gupta, S Vangeti, J Pourazar, A Discacciat, J Höijer, M Bottai, NK Björkström, J Rasmuson, M Evander, A Blomberg, HG Ljunggren, J Klingström, C Ahlm, A Smed-Sören
PLoS Pathog., 2017-06-22;13(6):e1006462.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Construction and Screening of a Lentiviral Secretome Library
Authors: T Liu, P Jia, H Ma, SA Reed, X Luo, HB Larman, PG Schultz
Cell Chem Biol, 2017-06-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Susceptibility to Cryptococcal Meningoencephalitis Associated With Idiopathic CD4(+) Lymphopenia and Secondary Germline or Acquired Defects
Authors: AA Panackal, LB Rosen, G Uzel, MJ Davis, G Hu, A Adeyemo, F Tekola-Aye, A Lisco, C Diachok, JD Kim, D Shaw, I Sereti, J Stoddard, J Niemela, SD Rosenzweig, JE Bennett, PR Williamson
Open Forum Infect Dis, 2017-06-07;4(2):ofx082.
Species: Human
Sample Types: Plasma
Applications: Bioassay -
Differential Th17 response induced by the two clades of the pandemic ST258 Klebsiella pneumoniae clonal lineages producing KPC-type carbapenemase
Authors: AM Clemente, G Castronovo, A Antonelli, MM D'Andrea, M Tanturli, E Perissi, S Paccosi, A Parenti, F Cozzolino, GM Rossolini, MG Torcia
PLoS ONE, 2017-06-06;12(6):e0178847.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise
Authors: H Zhao, S Gulesseria, MC Malinao, S Kumar-Gane, J Song, MS Chang, MM Williams, Z Zeng, M Mattie, BA Mendelsohn, DR Stover, F Doñate
Mol. Cancer Ther., 2017-05-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: Implications for calcification-related chronic inflammatory diseases
Authors: CSB Viegas, RM Costa, L Santos, PA Videira, Z Silva, N Araújo, AL Macedo, AP Matos, C Vermeer, DC Simes
PLoS ONE, 2017-05-18;12(5):e0177829.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CXCL4 Exposure Potentiates TLR-Driven Polarization of Human Monocyte-Derived Dendritic Cells and Increases Stimulation of T Cells
Authors: SC Silva-Card, AJ Affandi, L Spel, M Cossu, JAG van Roon, M Boes, TRDJ Radstake
J. Immunol., 2017-05-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Identification of SERINC5-001 as the Predominant Spliced Isoform for HIV-1 Restriction
Authors: X Zhang, T Zhou, J Yang, Y Lin, J Shi, X Zhang, DA Frabutt, X Zeng, S Li, PJ Venta, YH Zheng
J. Virol, 2017-04-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Oil-Soluble Contrast Medium (OSCM) for Hysterosalpingography Modulates Dendritic Cell and Regulatory T Cell Profiles in the Peritoneal Cavity: A Possible Mechanism by Which OSCM Enhances Fertility
Authors: G Izumi, K Koga, M Takamura, W Bo, M Nagai, M Miyashita, M Harada, T Hirata, Y Hirota, O Yoshino, T Fujii, Y Osuga
J. Immunol., 2017-04-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cancer-derived Circulating MicroRNAs Promote Tumor Angiogenesis by Entering Dendritic Cells to Degrade Highly Complementary MicroRNAs
Authors: J Wang, H Ye, D Zhang, K Cheng, Y Hu, X Yu, L Lu, J Hu, C Zuo, B Qian, Y Yu, S Liu, G Liu, C Mao, S Liu
Theranostics, 2017-03-24;7(6):1407-1421.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Vaccination targeting native receptors to enhance the function and proliferation of chimeric antigen receptor (CAR)-modified T cells
Authors: M Tanaka, H Tashiro, B Omer, N Lapteva, J Ando, M Ngo, B Mehta, G Dotti, PR Kinchingto, AM Leen, C Rossig, CM Rooney
Clin. Cancer Res, 2017-02-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dendritic cell MST1 inhibits Th17 differentiation
Authors: C Li, Y Bi, Y Li, H Yang, Q Yu, J Wang, Y Wang, H Su, A Jia, Y Hu, L Han, J Zhang, S Li, W Tao, G Liu
Nat Commun, 2017-02-01;8(0):14275.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1
Authors: JE Hammonds, N Beeman, L Ding, S Takushi, AC Francis, JJ Wang, GB Melikyan, P Spearman
PLoS Pathog, 2017-01-27;13(1):e1006181.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Targeting GM-CSF in epithelial and vascular remodeling in experimental Eosinophilic Esophagitis
Authors: Eóin N McNamee
Allergy, 2017-01-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
IL-3 Up-regulates and Activates Human Eosinophil CD32 and ?M�2 Integrin Causing Degranulation
Authors: Stephane Esnault
Clin. Exp. Allergy, 2017-01-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Mycobacterium tuberculosis ESAT6 and CPF10 Induce Adenosine Deaminase 2 mRNA Expression in Monocyte-Derived Macrophages
Authors: MJ Bae, S Ryu, HJ Kim, SI Cha, CH Kim, J Lee
Tuberc Respir Dis (Seoul), 2016-12-30;80(1):77-82.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators
Authors: A Dyer, Y Di, H Calderon, S Illingwort, G Kueberuwa, A Tedcastle, P Jakeman, SL Chia, A Brown, MA Silva, D Barlow, J Beadle, T Hermiston, DJ Ferguson, B Champion, KD Fisher, LW Seymour
Mol Ther Oncolytics, 2016-12-10;4(0):18-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
1400W ameliorates acute hypobaric hypoxia/reoxygenation-induced cognitive deficits by suppressing the induction of inducible nitric oxide synthase in rat cerebral cortex microglia
Authors: Jiang Zheng
Behav. Brain Res., 2016-11-22;319(0):188-199.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Comparative analysis of the interaction of HSPs in dendritic cells, macrophages, RGM-1 cells infected by Helicobacter pylori
Authors: Guangxin Li
Am J Transl Res, 2016-10-15;8(10):4184-4194.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Functional IL-33 receptors are expressed in early progenitor stages of allergy-related granulocytes
Immunology, 2016-09-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Peritumoral stromal neutrophils are essential for c-Met-elicited metastasis in human hepatocellular carcinoma
Authors: Xiang-Ming Lao
Oncoimmunology, 2016-09-27;5(10):e1219828.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CD11c/CD18 Dominates Adhesion of Human Monocytes, Macrophages and Dendritic Cells over CD11b/CD18
PLoS ONE, 2016-09-22;11(9):e0163120.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The interplay of epigenetic therapy and immunity in locally recurrent or metastatic estrogen receptor-positive breast cancer: Correlative analysis of ENCORE 301, a randomized, placebo-controlled phase II trial of exemestane with or without entinostat
Authors: Yusuke Tomita
Oncoimmunology, 2016-08-31;5(11):e1219008.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation
J Clin Invest, 2016-08-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation
J Immunol, 2016-08-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Bacterial Manipulation of NK Cell Regulatory Activity Increases Susceptibility to Listeria monocytogenes Infection
Authors: Sarah E Clark
PLoS Pathog, 2016-06-13;12(6):e1005708.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Melanoma Cells Can Adopt the Phenotype of Stromal Fibroblasts and Macrophages by Spontaneous Cell Fusion in Vitro
Authors: Lajos V Kemény
Int J Mol Sci, 2016-06-02;17(6):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human mesenchymal stromal cell-secreted lactate induces M2-macrophage differentiation by metabolic reprogramming
Oncotarget, 2016-05-24;7(21):30193-210.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CD99 isoforms regulate CD1a expression in human monocyte-derived DCs through ATF-2/CREB-1 phosphorylation
Authors: K Mahiddine, A Mallaviall, H Bziouech, F Larbret, A Bernard, G Bernard
Eur J Immunol, 2016-05-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Decitabine enhances anti-CD33 monoclonal antibody BI 836858-mediated natural killer ADCC against AML blasts
Blood, 2016-03-24;127(23):2879-89.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Enhanced Cytotoxic CD8 T Cell Priming Using Dendritic Cell-Expressing Human Papillomavirus-16 E6/E7-p16INK4 Fusion Protein with Sequenced Anti-Programmed Death-1
Authors: TM Garcia-Bat, E Kim, F Concha-Ben, S Trivedi, RB Mailliard, A Gambotto, RL Ferris
J. Immunol, 2016-02-05;196(6):2870-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.
Authors: Younis R, Han K, Webb T
J Immunol, 2016-01-06;196(3):1419-29.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence.
Authors: Tufariello J, Chapman J, Kerantzas C, Wong K, Vilcheze C, Jones C, Cole L, Tinaztepe E, Thompson V, Fenyo D, Niederweis M, Ueberheide B, Philips J, Jacobs W
Proc Natl Acad Sci U S A, 2016-01-04;113(3):E348-57.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Preferential Induction of the T Cell Auxiliary Signaling Molecule B7-H3 on Synovial Monocytes in Rheumatoid Arthritis
Authors: BR Yoon, YH Chung, SJ Yoo, K Kawara, J Kim, IS Yoo, CG Park, SW Kang, WW Lee
J. Biol. Chem, 2015-12-23;291(8):4048-57.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Identification of Four-Jointed Box 1 (FJX1)-Specific Peptides for Immunotherapy of Nasopharyngeal Carcinoma.
Authors: Chai S, Yap Y, Foo Y, Yap L, Ponniah S, Teo S, Cheong S, Patel V, Lim K
PLoS ONE, 2015-11-04;10(11):e0130464.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
GSK3beta inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells.
Authors: Kitajima K, Nakajima M, Kanokoda M, Kyba M, Dandapat A, Tolar J, Saito M, Toyoda M, Umezawa A, Hara T
Exp Hematol, 2015-10-23;44(1):68-74.e10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?
Authors: Spampinato S, Obermeier B, Cotleur A, Love A, Takeshita Y, Sano Y, Kanda T, Ransohoff R
PLoS ONE, 2015-07-21;10(7):e0133392.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Identification of resolvin D2 receptor mediating resolution of infections and organ protection.
Authors: Chiang N, Dalli J, Colas R, Serhan C
J Exp Med, 2015-07-20;212(8):1203-17.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.
Authors: Eigenbrod T, Pelka K, Latz E, Kreikemeyer B, Dalpke A
J Immunol, 2015-06-22;195(3):1092-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma.
Authors: Yousef S, Heise J, Lajmi N, Bartels K, Kroger N, Luetkens T, Atanackovic D
J Transl Med, 2015-06-20;13(0):197.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo.
Authors: Ptaschinski C, Mukherjee S, Moore M, Albert M, Helin K, Kunkel S, Lukacs N
PLoS Pathog, 2015-06-17;11(6):e1004978.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Faecalibacterium prausnitzii Strain HTF-F and Its Extracellular Polymeric Matrix Attenuate Clinical Parameters in DSS-Induced Colitis.
Authors: Rossi O, Khan M, Schwarzer M, Hudcovic T, Srutkova D, Duncan S, Stolte E, Kozakova H, Flint H, Samsom J, Harmsen H, Wells J
PLoS ONE, 2015-04-24;10(4):e0123013.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Wear particles derived from metal hip implants induce the generation of multinucleated giant cells in a 3-dimensional peripheral tissue-equivalent model.
Authors: Dutta D, Potnis P, Rhodes K, Wood S
PLoS ONE, 2015-04-20;10(4):e0124389.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Integrated innate mechanisms involved in airway allergic inflammation to the serine protease subtilisin.
Authors: Florsheim E, Yu S, Bragatto I, Faustino L, Gomes E, Ramos R, Barbuto J, Medzhitov R, Russo M
J Immunol, 2015-04-15;194(10):4621-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Histamine promotes the development of monocyte-derived dendritic cells and reduces tumor growth by targeting the myeloid NADPH oxidase.
Authors: Martner A, Wiktorin H, Lenox B, Ewald Sander F, Aydin E, Aurelius J, Thoren F, Stahlberg A, Hermodsson S, Hellstrand K
J Immunol, 2015-04-13;194(10):5014-21.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Molecular mechanisms linking high dose medroxyprogesterone with HIV-1 risk.
Authors: Irvin S, Herold B
PLoS ONE, 2015-03-23;10(3):e0121135.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation.
Authors: Baharom F, Thomas S, Bieder A, Hellmer M, Volz J, Sandgren K, McInerney G, Karlsson Hedestam G, Mellman I, Smed-Sorensen A
J Immunol, 2015-03-23;194(9):4422-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Paracoccidioides brasiliensis interferes on dendritic cells maturation by inhibiting PGE2 production.
Authors: Fernandes R, Bachiega T, Rodrigues D, Golim M, Dias-Melicio L, Balderramas H, Kaneno R, Soares A
PLoS ONE, 2015-03-20;10(3):e0120948.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Physiologic concentrations of HMGB1 have no impact on cytokine-mediated eosinophil survival or chemotaxis in response to Eotaxin-2 (CCL24).
Authors: Dyer, Kimberly, Rosenberg, Helene F
PLoS ONE, 2015-03-16;10(3):e0118887.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
SOCS3 silencing attenuates eosinophil functions in asthma patients.
Authors: Zafra M, Canas J, Mazzeo C, Gamez C, Sanz V, Fernandez-Nieto M, Quirce S, Barranco P, Ruiz-Hornillos J, Sastre J, del Pozo V
Int J Mol Sci, 2015-03-10;16(3):5434-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Type I IFNs and IL-18 regulate the antiviral response of primary human gammadelta T cells against dendritic cells infected with Dengue virus.
Authors: Tsai C, Liong K, Gunalan M, Li N, Lim D, Fisher D, Macary P, Leo Y, Wong S, Puan K, Wong S
J Immunol, 2015-03-02;194(8):3890-900.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dendritic cell SIRT1-HIF1alpha axis programs the differentiation of CD4+ T cells through IL-12 and TGF-beta1.
Authors: Liu G, Bi Y, Xue L, Zhang Y, Yang H, Chen X, Lu Y, Zhang Z, Liu H, Wang X, Wang R, Chu Y, Yang R
Proc Natl Acad Sci U S A, 2015-02-17;112(9):E957-65.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The role of phosphoinositide 3-kinases in neutrophil migration in 3D collagen gels.
Authors: Martin, Kayleigh, Muessel, Michelle, Pullar, Christin, Willars, Gary B, Wardlaw, Andrew J
PLoS ONE, 2015-02-06;10(2):e0116250.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Viral semaphorin inhibits dendritic cell phagocytosis and migration but is not essential for gammaherpesvirus-induced lymphoproliferation in malignant catarrhal fever.
Authors: Myster F, Palmeira L, Sorel O, Bouillenne F, DePauw E, Schwartz-Cornil I, Vanderplasschen A, Dewals B
J Virol, 2015-01-14;89(7):3630-47.
Species: Rabbit
Sample Types: Whole Cells
Applications: Bioassay -
Transcriptome analysis of Kaposi's sarcoma-associated herpesvirus during de novo primary infection of human B and endothelial cells.
Authors: Purushothaman P, Thakker S, Verma S
J Virol, 2014-12-31;89(6):3093-111.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CD40L induces functional tunneling nanotube networks exclusively in dendritic cells programmed by mediators of type 1 immunity.
Authors: Zaccard C, Watkins S, Kalinski P, Fecek R, Yates A, Salter R, Ayyavoo V, Rinaldo C, Mailliard R
J Immunol, 2014-12-29;194(3):1047-56.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.
Authors: Lam, Sharon, Sung, Julia, Cruz, Conrad, Castillo-Caro, Paul, Ngo, Minhtran, Garrido, Carolina, Kuruc, Joann, Archin, Nancie, Rooney, Cliona, Margolis, David, Bollard, Catherin
Mol Ther, 2014-11-04;23(2):387-95.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cytotoxicity of human endogenous retrovirus K-specific T cells toward autologous ovarian cancer cells.
Authors: Rycaj K, Plummer J, Yin B, Li M, Garza J, Radvanyi L, Ramondetta L, Lin K, Johanning G, Tang D, Wang-Johanning F
Clin Cancer Res, 2014-11-04;21(2):471-83.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes.
Authors: Gallagher K, Joshi A, Carson W, Schaller M, Allen R, Mukerjee S, Kittan N, Feldman E, Henke P, Hogaboam C, Burant C, Kunkel S
Diabetes, 2014-11-03;64(4):1420-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Granulocyte-Colony Stimulating Factor related pathways tested on an endometrial ex-vivo model.
Authors: Rahmati M, Petitbarat M, Dubanchet S, Bensussan A, Chaouat G, Ledee N
PLoS ONE, 2014-10-02;9(9):e102286.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay -
B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets.
Authors: Kuang D, Xiao X, Zhao Q, Chen M, Li X, Liu R, Wei Y, Ouyang F, Chen D, Wu Y, Lao X, Deng H, Zheng L
J Clin Invest, 2014-09-17;124(10):4657-67.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dendritic cell CD83 homotypic interactions regulate inflammation and promote mucosal homeostasis.
Authors: Bates J, Flanagan K, Mo L, Ota N, Ding J, Ho S, Liu S, Roose-Girma M, Warming S, Diehl L
Mucosal Immunol, 2014-09-10;8(2):414-28.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion.
Authors: Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, Marti L
PLoS ONE, 2014-09-03;9(9):e106673.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1.
Authors: Hedl M, Abraham C
Proc Natl Acad Sci U S A, 2014-09-02;111(37):13451-6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dengue virus-infected human dendritic cells reveal hierarchies of naturally expressed novel NS3 CD8 T cell epitopes.
Authors: Piazza P, Campbell D, Marques E, Hildebrand W, Buchli R, Mailliard R, Rinaldo C
Clin Exp Immunol, 2014-09-01;177(3):696-702.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Immunopathogenesis of HIV infection in cocaine users: role of arachidonic acid.
Authors: Samikkannu T, Rao K, Ding H, Agudelo M, Raymond A, Yoo C, Nair M
PLoS ONE, 2014-08-29;9(8):e106348.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors.
Authors: Anderson J, Titz B, Akiyama R, Komisopoulou E, Park A, Tap W, Graeber T, Denny C
Mol Cancer Res, 2014-08-04;12(12):1740-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A whole recombinant yeast-based therapeutic vaccine elicits HBV X, S and Core specific T cells in mice and activates human T cells recognizing epitopes linked to viral clearance.
Authors: King T, Kemmler C, Guo Z, Mann D, Lu Y, Coeshott C, Gehring A, Bertoletti A, Ho Z, Delaney W, Gaggar A, Subramanian G, McHutchison J, Shrivastava S, Lee Y, Kottilil S, Bellgrau D, Rodell T, Apelian D
PLoS ONE, 2014-07-22;9(7):e101904.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Stimulation -
Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages.
Authors: Deng B, Wang C, Arnardottir H, Li Y, Cheng C, Dalli J, Serhan C
PLoS ONE, 2014-07-18;9(7):e102362.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Live attenuated B. pertussis BPZE1 rescues the immune functions of Respiratory Syncytial virus infected human dendritic cells by promoting Th1/Th17 responses.
Authors: Schiavoni I, Fedele G, Quattrini A, Bianco M, Schnoeller C, Openshaw P, Locht C, Ausiello C
PLoS ONE, 2014-06-26;9(6):e100166.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
NK cells are primed by ANRS MVA(HIV)-infected DCs, via a mechanism involving NKG2D and membrane-bound IL-15, to control HIV-1 infection in CD4+ T cells.
Authors: Moreno-Nieves U, Didier C, Levy Y, Barre-Sinoussi F, Scott-Algara D
Eur J Immunol, 2014-06-24;44(8):2370-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dendritic cells restore CD8+ T cell reactivity to autologous HIV-1.
Authors: Smith K, Mailliard R, Larsen B, Wong K, Gupta P, Mullins J, Rinaldo C
J Virol, 2014-06-18;88(17):9976-90.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cutting edge: Parathyroid hormone facilitates macrophage efferocytosis in bone marrow via proresolving mediators resolvin D1 and resolvin D2.
Authors: McCauley L, Dalli J, Koh A, Chiang N, Serhan C
J Immunol, 2014-06-02;193(1):26-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways.
Authors: Hedl M, Zheng S, Abraham C
J Immunol, 2014-05-19;192(12):5924-32.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Direct induction of ramified microglia-like cells from human monocytes: dynamic microglial dysfunction in Nasu-Hakola disease.
Authors: Ohgidani, Masahiro, Kato, Takahiro, Setoyama, Daiki, Sagata, Noriaki, Hashimoto, Ryota, Shigenobu, Kazue, Yoshida, Tetsuhik, Hayakawa, Kohei, Shimokawa, Norihiro, Miura, Daisuke, Utsumi, Hideo, Kanba, Shigenob
Sci Rep, 2014-05-14;4(0):4957.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Canine distemper virus infection leads to an inhibitory phenotype of monocyte-derived dendritic cells in vitro with reduced expression of co-stimulatory molecules and increased interleukin-10 transcription.
Authors: Qeska V, Barthel Y, Herder V, Stein V, Tipold A, Urhausen C, Gunzel-Apel A, Rohn K, Baumgartner W, Beineke A
PLoS ONE, 2014-04-25;9(4):e96121.
Species: Canine
Sample Types: Whole Cells
Applications: Bioassay -
Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas.
Authors: Picco G, Beatson R, Taylor-Papadimitriou J, Burchell J
Eur J Immunol, 2014-04-17;44(7):1947-55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Monocyte to macrophage differentiation goes along with modulation of the plasmalogen pattern through transcriptional regulation.
Authors: Wallner S, Grandl M, Konovalova T, Sigruner A, Kopf T, Peer M, Orso E, Liebisch G, Schmitz G
PLoS ONE, 2014-04-08;9(4):e94102.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
HIV-1 Nef impairs key functional activities in human macrophages through CD36 downregulation.
Authors: Olivetta E, Tirelli V, Chiozzini C, Scazzocchio B, Romano I, Arenaccio C, Sanchez M
PLoS ONE, 2014-04-04;9(4):e93699.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neuropeptide Y induces potent migration of human immature dendritic cells and promotes a Th2 polarization.
Authors: Buttari B, Profumo E, Domenici G, Tagliani A, Ippoliti F, Bonini S, Businaro R, Elenkov I, Rigano R
FASEB J, 2014-04-03;28(7):3038-49.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Anti-granulocyte-macrophage colony-stimulating factor autoantibodies are a risk factor for central nervous system infection by Cryptococcus gattii in otherwise immunocompetent patients.
Authors: Saijo, Tomomi, Chen, Jianghan, Chen, Sharon C, Rosen, Lindsey, Yi, Jin, Sorrell, Tania C, Bennett, John E, Holland, Steven M, Browne, Sarah K, Kwon-Chung, Kyung J
MBio, 2014-03-18;5(2):e00912-14.
Species: Human
Sample Types: Plasma
Applications: Bioassay -
Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infection.
Authors: Umashankar, Mahadeva, Rak, Michael, Bughio, Farah, Zagallo, Patricia, Caviness, Katie, Goodrum, Felicia
J Virol, 2014-03-12;88(11):5987-6002.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The molecule of DC-SIGN captures enterovirus 71 and confers dendritic cell-mediated viral trans-infection.
Authors: Ren X, Ma L, Liu Q, Li C, Huang Z, Wu L, Xiong S, Wang J, Wang H
Virol J, 2014-03-12;11(0):47.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure.
Authors: Llop-Guevara A, Chu D, Walker T, Goncharova S, Fattouh R, Silver J, Moore C, Xie J, O'Byrne P, Coyle A, Kolbeck R, Humbles A, Stampfli M, Jordana M
PLoS ONE, 2014-02-14;9(2):e88714.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Adenovirus-based vaccines against rhesus lymphocryptovirus EBNA-1 induce expansion of specific CD8+ and CD4+ T cells in persistently infected rhesus macaques.
Authors: Leskowitz, R, Fogg, M H, Zhou, X Y, Kaur, A, Silveira, E L V, Villinger, F, Lieberman, P M, Wang, F, Ertl, H C
J Virol, 2014-02-12;88(9):4721-35.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay -
Fusion of ubiquitin to HIV gag impairs human monocyte-derived dendritic cell maturation and reduces ability to induce gag T cell responses.
Authors: Herath S, Benlahrech A, Papagatsias T, Athanasopoulos T, Bouzeboudjen Z, Hervouet C, Klavinskis L, Meiser A, Kelleher P, Dickson G, Patterson S
PLoS ONE, 2014-02-05;9(2):e88327.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Characterization of the structure and immunostimulatory activity of a vaccine adjuvant, de-O-acylated lipooligosaccharide.
Authors: Han, Ji Eun, Wui, Seo Ri, Kim, Kwang Su, Cho, Yang Je, Cho, Wan Je, Lee, Na Gyong
PLoS ONE, 2014-01-22;9(1):e85838.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
Authors: Sawada H, Saito T, Nickel N, Alastalo T, Glotzbach J, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai Y, Perez V, Kim Y, Wang L, Chen P, Spiekerkoetter E, Mitani Y, Gurtner G, Sarnow P, Rabinovitch M
J Exp Med, 2014-01-20;211(2):263-80.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Tie2 signaling cooperates with TNF to promote the pro-inflammatory activation of human macrophages independently of macrophage functional phenotype.
Authors: Garcia S, Krausz S, Ambarus C, Fernandez B, Hartkamp L, van Es I, Hamann J, Baeten D, Tak P, Reedquist K
PLoS ONE, 2014-01-03;9(1):e82088.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The IL-23/Th17 axis is involved in the adaptive immune response to Bacillus anthracis in humans.
Authors: Harris K, Ramachandran G, Basu S, Rollins S, Mann D, Cross A
Eur J Immunol, 2014-01-02;44(3):752-62.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
High activities of BACE1 in brains with mild cognitive impairment.
Authors: Cheng X, He P, Lee T, Yao H, Li R, Shen Y
Am J Pathol, 2014-01-01;184(1):141-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cocaine enhances HIV-1 infectivity in monocyte derived dendritic cells by suppressing microRNA-155.
Authors: Napuri, Jessica, Pilakka-Kanthikeel, Sudheesh, Raymond, Andrea, Agudelo, Marisela, Yndart-Arias, Adriana, Saxena, Shailend, Nair, Madhavan
PLoS ONE, 2013-12-31;8(12):e83682.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18.
Authors: Li W, Okuda A, Yamamoto H, Yamanishi K, Terada N, Yamanishi H, Tanaka Y, Okamura H
PLoS ONE, 2013-12-20;8(12):e82586.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation.
Authors: Klimenkova O, Ellerbeck W, Klimiankou M, Unalan M, Kandabarau S, Gigina A, Hussein K, Zeidler C, Welte K, Skokowa J
Blood, 2013-12-18;123(8):1239-49.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
An investigation into IgE-facilitated allergen recognition and presentation by human dendritic cells.
Authors: Sharquie I, Al-Ghouleh A, Fitton P, Clark M, Armour K, Sewell H, Shakib F, Ghaemmaghami A
BMC Immunol, 2013-12-13;14(0):54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Characterization of CD56+ dendritic-like cells: a normal counterpart of blastic plasmacytoid dendritic cell neoplasm?
Authors: Osaki Y, Yokohama A, Saito A, Tahara K, Yanagisawa K, Ogawa Y, Ishizaki T, Mitsui T, Koiso H, Takizawa M, Uchiumi H, Saitoh T, Handa H, Murakami H, Tsukamoto N, Nojima Y
PLoS ONE, 2013-11-29;8(11):e81722.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Restricted 5'-end gap repair of HIV-1 integration due to limited cellular dNTP concentrations in human primary macrophages.
Authors: Van Cor-Hosmer S, Kim D, Daly M, Daddacha W, Kim B
J Biol Chem, 2013-10-04;288(46):33253-62.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Endogenous erythroid colony formation in chronic myeloid leukemia: a recurrent finding associated with persistent minimal residual disease under imatinib.
Authors: Einwallner E, Jaeger E, Mitterbauer-Hohendanner G, Bilban M, Simonitsch-Klupp I, Steiner I, Pernicka E, Hoermann G, Herndlhofer S, Sillaber C, Valent P, Schwarzinger I
Stem Cells Dev, 2013-09-04;22(23):3043-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments.
Authors: Marwick, John A, Dorward, David A, Lucas, Christop, Jones, Katie O, Sheldrake, Tara A, Fox, Sarah, Ward, Carol, Murray, Joanna, Brittan, Mairi, Hirani, Nik, Duffin, Rodger, Dransfield, Ian, Haslett, Christop, Rossi, Adriano
J Leukoc Biol, 2013-08-20;94(6):1285-92.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Functional neuroprotection and efficient regulation of GDNF using destabilizing domains in a rodent model of Parkinson's disease.
Authors: Quintino L, Manfre G, Wettergren E, Namislo A, Isaksson C, Lundberg C
Mol Ther, 2013-07-24;21(12):2169-80.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines.
Authors: Spiess C, Bevers J, Jackman J, Chiang N, Nakamura G, Dillon M, Liu H, Molina P, Elliott J, Shatz W, Scheer J, Giese G, Persson J, Zhang Y, Dennis M, Giulianotti J, Gupta P, Reilly D, Palma E, Wang J, Stefanich E, Scheerens H, Fuh G, Wu L
J Biol Chem, 2013-07-23;288(37):26583-93.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease.
Authors: Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume M, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T
Immunology, 2013-05-01;139(1):19-29.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Genome-wide analysis of alternative splicing during dendritic cell response to a bacterial challenge.
Authors: Rodrigues R, Grosso A, Moita L
PLoS ONE, 2013-04-17;8(4):e61975.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Hepatitis B virus surface antigen selectively inhibits TLR2 ligand-induced IL-12 production in monocytes/macrophages by interfering with JNK activation.
Authors: Wang S, Chen Z, Hu C, Qian F, Cheng Y, Wu M, Shi B, Chen J, Hu Y, Yuan Z
J Immunol, 2013-04-12;190(10):5142-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Clinical-grade multipotent adult progenitor cells durably control pathogenic T cell responses in human models of transplantation and autoimmunity.
Authors: Reading J, Yang J, Sabbah S, Skowera A, Knight R, Pinxteren J, Vaes B, Allsopp T, Ting A, Busch S, Raber A, Deans R, Tree T
J Immunol, 2013-04-01;190(9):4542-52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Griffithsin protects mice from genital herpes by preventing cell-to-cell spread.
Authors: Nixon, Briana, Stefanidou, Martha, Mesquita, Pedro M, Fakioglu, Esra, Segarra, Theodore, Rohan, Lisa, Halford, William, Palmer, Kenneth, Herold, Betsy C
J Virol, 2013-03-27;87(11):6257-69.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Interleukin-27 is a potent inhibitor of cis HIV-1 replication in monocyte-derived dendritic cells via a type I interferon-independent pathway.
Authors: Chen, Qian, Swaminathan, Sanjay, Yang, De, Dai, Lue, Sui, Hongyan, Yang, Jun, Hornung, Ronald L, Wang, Yanmei, Huang, Da Wei, Hu, Xiaojun, Lempicki, Richard, Imamichi, Tomozumi
PLoS ONE, 2013-03-20;8(3):e59194.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis.
Authors: Rosen L, Freeman A, Yang L, Jutivorakool K, Olivier K, Angkasekwinai N, Suputtamongkol Y, Bennett J, Pyrgos V, Williamson P, Ding L, Holland S, Browne S
J Immunol, 2013-03-18;190(8):3959-66.
Species: Human
Sample Types: Plasma
Applications: Bioassay -
Surfactant Protein D modulates HIV infection of both T-cells and dendritic cells.
Authors: Madsen J, Gaiha G, Palaniyar N, Dong T, Mitchell D, Clark H
PLoS ONE, 2013-03-18;8(3):e59047.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype.
Authors: Dalli J, Zhu M, Vlasenko N, Deng B, Haeggstrom J, Petasis N, Serhan C
FASEB J, 2013-03-15;27(7):2573-83.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-gamma memory in human CD4(+) T lymphocytes.
Authors: Dong J, Chang H, Ivascu C, Qian Y, Rezai S, Okhrimenko A, Cosmi L, Maggi L, Eckhardt F, Wu P, Sieper J, Alexander T, Annunziato F, Gossen M, Li J, Radbruch A, Thiel A
Eur J Immunol, 2013-03-01;43(3):793-804.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients.
Authors: Srivastava R, Lee S, Andrade Filho P, Lord C, Jie H, Davidson H, Lopez-Albaitero A, Gibson S, Gooding W, Ferrone S, Ferris R
Clin Cancer Res, 2013-02-26;19(7):1858-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia.
Authors: Yu, Jianhua, Peng, Yong, Wu, Lai-Chu, Xie, Zhiliang, Deng, Youcai, Hughes, Tiffany, He, Shun, Mo, XiaoKui, Chiu, Ming, Wang, Qi-En, He, Xiaoming, Liu, Shujun, Grever, Michael, Chan, Kenneth, Liu, Zhongfa
PLoS ONE, 2013-02-13;8(2):e55934.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cord-blood-derived mesenchymal stromal cells downmodulate CD4+ T-cell activation by inducing IL-10-producing Th1 cells.
Authors: Selleri S, Dieng M, Nicoletti S, Louis I, Beausejour C, Le Deist F, Haddad E
Stem Cells Dev, 2013-01-04;22(7):1063-75.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
Authors: Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, Boireau W, Simon B, Ryffel B, Connat J, Kanellopoulos J, Martin F, Rebe C, Apetoh L, Ghiringhelli F
Nat Med, 2012-12-02;19(1):57-64.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients.
Authors: Brusic, Ana, Hainz, Ursula, Wadleigh, Martha, Neuberg, Donna, Su, Mei, Canning, Christin, Deangelo, Daniel J, Stone, Richard, Lee, Jeng-Shi, Mulligan, Richard, Ritz, Jerome, Dranoff, Glenn, Sasada, Tetsuro, Wu, Catherin
Oncoimmunology, 2012-10-01;1(7):1095-1103.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates.
Eur. J. Immunol., 2012-07-04;42(8):2019-30.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: Bioassay -
Nitric oxide-producing myeloid-derived suppressor cells inhibit vascular E-selectin expression in human squamous cell carcinomas.
J. Invest. Dermatol., 2012-06-21;132(11):2642-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase.
Authors: Graham LM, Gupta V, Schafer G, Reid DM, Kimberg M, Dennehy KM, Hornsell WG, Guler R, Campanero-Rhodes MA, Palma AS, Feizi T, Kim SK, Sobieszczuk P, Willment JA, Brown GD
J. Biol. Chem., 2012-06-11;287(31):25964-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Leishmania amazonensis impairs DC function by inhibiting CD40 expression via A2B adenosine receptor activation.
Authors: Figueiredo AB, Serafim TD, Marques-da-Silva EA, Meyer-Fernandes JR, Afonso LC
Eur. J. Immunol., 2012-05-01;42(5):1203-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation.
Authors: Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M
Eur. J. Immunol., 2012-04-01;42(4):936-45.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Severe dermatitis with loss of epidermal Langerhans cells in human and mouse zinc deficiency.
Authors: Kawamura T, Ogawa Y, Nakamura Y
J. Clin. Invest., 2012-01-03;122(2):722-32.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite.
Authors: Emara M, Royer PJ, Mahdavi J
J. Biol. Chem., 2011-12-28;287(8):5756-63.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Erythropoietin mimetic compound AGEM400(HES) binds to the same receptor as erythropoietin but displays a different spectrum of activities.
Authors: Kessler C, Greindl A, Breuer B, Haberl U, Rybka A, Emgenbroich M, Frank HG, Potgens AJ
Cytokine, 2011-12-03;57(2):226-37.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells.
Authors: Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC
Leukemia, 2010-11-19;25(1):161-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies.
Authors: Peressin M, Holl V, Schmidt S, Decoville T, Mirisky D, Lederle A, Delaporte M, Xu K, Aubertin AM, Moog C
J. Virol., 2010-11-17;85(2):1077-85.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression.
Authors: Xu H, Wang X, Pahar B
J. Immunol., 2010-11-08;185(12):7340-8.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay -
CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response.
Authors: Zhang HH, Song K, Rabin RL, Hill BJ, Perfetto SP, Roederer M, Douek DC, Siegel RM, Farber JM
J. Immunol., 2010-10-27;185(11):6646-63.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dynamic interaction networks in a hierarchically organized tissue.
Authors: Kirouac DC, Ito C, Csaszar E, Roch A, Yu M, Sykes EA, Bader GD, Zandstra PW
Mol. Syst. Biol., 2010-10-05;6(0):417.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration.
Authors: Johnson LA, Jackson DG
Int. Immunol., 2010-08-25;22(10):839-49.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Inhibition of dynamin-dependent endocytosis interferes with type III IFN expression in bacteria-infected human monocyte-derived DCs.
Authors: Pietila TE, Latvala S, Osterlund P, Julkunen I
J. Leukoc. Biol., 2010-07-07;88(4):665-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells.
Authors: Ghirelli C, Zollinger R, Soumelis V
Blood, 2010-04-09;115(24):5037-40.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human pregnancy specific beta-1-glycoprotein 1 (PSG1) has a potential role in placental vascular morphogenesis.
Authors: Ha CT, Wu JA, Irmak S, Lisboa FA, Dizon AM, Warren JW, Ergun S, Dveksler GS
Biol. Reprod., 2010-03-24;83(1):27-35.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TSLP and downstream molecules in experimental mouse allergic conjunctivitis.
Authors: Zheng X, Ma P, De Paiva CS, Cunningham MA, Hwang CS, Pflugfelder SC, Li DQ
Invest. Ophthalmol. Vis. Sci., 2010-01-27;51(6):3076-82.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property.
Authors: Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, Azuma M, Kinoshita K, Batmunkh R, Rentsenhand B, Makino H, Ranjan P, Minakuchi K, Sone S
J. Immunol., 2009-12-15;183(12):8176-85.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms.
Authors: Correale J, Farez M
J. Immunol., 2009-10-07;183(9):5999-6012.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Osteopontin is expressed and functional in human eosinophils.
Authors: Puxeddu I, Berkman N, Ribatti D
Allergy, 2009-10-05;65(2):168-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses.
Authors: Duraisingham SS, Hornig J, Gotch F, Patterson S
J. Immunol., 2009-07-22;183(4):2242-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
IL-27 abrogates receptor activator of NF-kappa B ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos.
Authors: Furukawa M, Takaishi H, Takito J, Yoda M, Sakai S, Hikata T, Hakozaki A, Uchikawa S, Matsumoto M, Chiba K, Kimura T, Okada Y, Matsuo K, Yoshida H, Toyama Y
J. Immunol., 2009-07-20;183(4):2397-406.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases.
Authors: Margulis A, Nocka KH, Brennan AM, Deng B, Fleming M, Goldman SJ, Kasaian MT
J. Immunol., 2009-07-10;183(3):1739-50.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.
Authors: Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M
Eur. J. Immunol., 2009-05-01;39(5):1221-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Epitope specificity and clonality of EBV-specific CTLs used to treat posttransplant lymphoproliferative disease.
Authors: McAulay KA, Haque T, Urquhart G, Bellamy C, Guiretti D, Crawford DH
J. Immunol., 2009-03-15;182(6):3892-901.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Gram-positive bacteria enhance HIV-1 susceptibility in Langerhans cells, but not in dendritic cells, via Toll-like receptor activation.
Authors: Ogawa Y, Kawamura T, Kimura T, Ito M, Blauvelt A, Shimada S
Blood, 2009-03-11;113(21):5157-66.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Colocalization of the VEGF-R2 and the common IL-3/GM-CSF receptor beta chain to lipid rafts leads to enhanced p38 activation.
Authors: Saulle E, Riccioni R, Coppola S, Parolini I, Diverio D, Riti V, Mariani G, Laufer S, Sargiacomo M, Testa U
Br. J. Haematol., 2009-02-24;145(3):399-411.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
MMP dependence of fibroblast contraction and collagen production induced by human mast cell activation in a three-dimensional collagen lattice.
Authors: Margulis A, Nocka KH, Wood NL, Wolf SF, Goldman SJ, Kasaian MT
Am. J. Physiol. Lung Cell Mol. Physiol., 2008-12-05;296(2):L236-47.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
AP-1-controlled hepatocyte growth factor activation promotes keratinocyte migration via CEACAM1 and urokinase plasminogen activator/urokinase plasminogen receptor.
Authors: Schnickmann S, Camacho-Trullio D, Bissinger M, Eils R, Angel P, Schirmacher P, Szabowski A, Breuhahn K
J. Invest. Dermatol., 2008-11-20;129(5):1140-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils.
Authors: Rahmoun M, Moles JP, Pedretti N, Mathieu M, Fremaux I, Raison-Peyron N, Lecron JC, Yssel H, Pene J
J. Invest. Dermatol., 2008-10-09;129(3):671-81.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Osteoprotegerin decreases human osteoclast apoptosis by inhibiting the TRAIL pathway.
Authors: Chamoux E, Houde N, L'Eriger K, Roux S
J. Cell. Physiol., 2008-08-01;216(2):536-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Adenosine receptors in regulation of dendritic cell differentiation and function.
Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
Blood, 2008-06-17;112(5):1822-31.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A novel IL-1 family cytokine, IL-33, potently activates human eosinophils.
Authors: Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H
J. Allergy Clin. Immunol., 2008-06-01;121(6):1484-90.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
Exp. Hematol., 2008-05-27;36(8):1035-46.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12.
Authors: Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M
J. Immunol., 2008-05-01;180(9):6000-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes.
Authors: Wolk K, Witte K, Witte E, Proesch S, Schulze-Tanzil G, Nasilowska K, Thilo J, Asadullah K, Sterry W, Volk HD, Sabat R
J. Leukoc. Biol., 2008-02-15;83(5):1181-93.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Pre-eclampsia is associated with dendritic cell recruitment into the uterine decidua.
Authors: Huang SJ, Chen CP, Schatz F, Rahman M, Abrahams VM, Lockwood CJ
J. Pathol., 2008-02-01;214(3):328-36.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A critical role for Pin1 in allergic pulmonary eosinophilia in rats.
Authors: Esnault S, Rosenthal LA, Shen ZJ, Sedgwick JB, Szakaly RJ, Sorkness RL, Malter JS
J. Allergy Clin. Immunol., 2007-08-27;120(5):1082-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques.
Authors: Zahorchak AF, Kean LS, Tokita D, Turnquist HR, Abe M, Finke J, Hamby K, Rigby MR, Larsen CP, Thomson AW
Transplantation, 2007-07-27;84(2):196-206.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay -
Transcriptional response of human dendritic cells to Borrelia garinii--defective CD38 and CCR7 expression detected.
Authors: Hartiala P, Hytonen J, Pelkonen J, Kimppa K, West A, Penttinen MA, Suhonen J, Lahesmaa R, Viljanen MK
J. Leukoc. Biol., 2007-04-17;82(1):33-43.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Lewis X oligosaccharides targeting to DC-SIGN enhanced antigen-specific immune response.
Authors: Wang J, Zhang Y, Wei J, Zhang X, Zhang B, Zhu Z, Zou W, Wang Y, Mou Z, Ni B, Wu Y
Immunology, 2007-03-20;121(2):174-82.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.
Authors: Rajesh</LastName><ForeNam D</Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF
Stem Cells, 2007-02-01;25(2):490-9.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells.
Authors: Kurooka M, Kaneda Y
Cancer Res., 2007-01-01;67(1):227-36.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
C-reactive protein impairs human CD14+ monocyte-derived dendritic cell differentiation, maturation and function.
Authors: Zhang R, Becnel L, Li M, Chen C, Yao Q
Eur. J. Immunol., 2006-11-01;36(11):2993-3006.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia.
Authors: Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos GD, Papadaki HA
Exp. Hematol., 2006-10-01;34(10):1312-22.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Modification of TLR-induced activation of human dendritic cells by type I IFN: synergistic interaction with TLR4 but not TLR3 agonists.
Authors: Walker J, Tough DF
Eur. J. Immunol., 2006-07-01;36(7):1827-36.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production.
Authors: Vaknin-Dembinsky A, Balashov K, Weiner HL
J. Immunol., 2006-06-15;176(12):7768-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Tumor-derived TGFbeta-1 induces dendritic cell apoptosis in the sentinel lymph node.
Authors: Ito M, Minamiya Y, Kawai H, Saito S, Saito H, Nakagawa T, Imai K, Hirokawa M, Ogawa J
J. Immunol., 2006-05-01;176(9):5637-43.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
GM-CSF action in the CNS decreases food intake and body weight.
Authors: Reed JA, Clegg DJ, Smith KB, Tolod-Richer EG, Matter EK, Picard LS, Seeley RJ
J. Clin. Invest., 2005-11-01;115(11):3035-44.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo -
Death receptors, Fas and TRAIL receptors, are involved in human osteoclast apoptosis.
Authors: Roux S, Lambert-Comeau P, Saint-Pierre C, Lepine M, Sawan B, Parent JL
Biochem. Biophys. Res. Commun., 2005-07-22;333(1):42-50.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Growth hormone-induced stimulation of multilineage human hematopoiesis.
Authors: Hanley MB, Napolitano LA, McCune JM
Stem Cells, 2005-06-13;23(8):1170-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Effect of piceatannol in human monocyte-derived dendritic cells in vitro.
Authors: Takei M, Umeyama A, Arihara S, Matsumoto H
J Pharm Sci, 2005-05-01;94(5):974-82.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta.
Authors: Nagineni CN, Kutty V, Detrick B, Hooks JJ
J. Cell. Physiol., 2005-04-01;203(1):35-43.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma.
Authors: Pound JD, Batth BK, Johannessen I, Wood K
J. Immunol., 2005-03-01;174(5):3015-23.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human peripheral blood eosinophils induce angiogenesis.
Authors: Puxeddu I, Alian A, Piliponsky AM, Ribatti D, Panet A, Levi-Schaffer F
Int. J. Biochem. Cell Biol., 2005-03-01;37(3):628-36.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CC chemokines and transmigration of eosinophils in the presence of vascular cell adhesion molecule 1.
Authors: Yamamoto H, Nagata M, Sakamoto Y
Ann. Allergy Asthma Immunol., 2005-02-01;94(2):292-300.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Bioassay -
GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice.
Authors: Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB
Immunity, 2004-12-01;21(6):831-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function.
Authors: Godfrey WR, Spoden DJ, Ge YG, Baker SR, Liu B, Levine BL, June CH, Blazar BR, Porter SB
Blood, 2004-09-16;105(2):750-8.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Bioassay -
Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases.
Authors: Scapini P, Carletto A, Nardelli B, Calzetti F, Roschke V, Merigo F, Tamassia N, Pieropan S, Biasi D, Sbarbati A, Sozzani S, Bambara L, Cassatella MA
Blood, 2004-09-09;105(2):830-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
Authors: Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R
J. Immunol., 2004-09-01;173(5):3482-91.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Effects of antiasthmatic agents on the functions of peripheral blood monocyte-derived dendritic cells from atopic patients.
Authors: Saeki S, Matsuse H, Kondo Y, Machida I, Kawano T, Tomari S, Obase Y, Fukushima C, Kohno S
J. Allergy Clin. Immunol., 2004-09-01;114(3):538-44.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
IL-22 increases the innate immunity of tissues.
Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
Immunity, 2004-08-01;21(2):241-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes.
Authors: Johansson MW, Lye MH, Barthel SR, Duffy AK, Annis DS, Mosher DF
Am. J. Respir. Cell Mol. Biol., 2004-06-25;31(4):413-22.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.
Authors: Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM
Biochem. J., 2004-06-01;380(0):425-33.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.
Authors: Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T
Immunology, 2004-06-01;112(2):274-89.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures.
Authors: Godfrey WR, Ge YG, Spoden DJ, Levine BL, June CH, Blazar BR, Porter SB
Blood, 2004-03-18;104(2):453-61.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis.
Authors: Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N
Blood, 2003-09-25;103(3):1089-98.
Species: Human
Sample Types: Serum
Applications: SDS-Page -
DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells.
Authors: Tailleux L, Schwartz O, Herrmann JL, Pivert E, Jackson M, Amara A, Legres L, Dreher D, Nicod LP, Gluckman JC, Lagrange PH, Gicquel B, Neyrolles O
J. Exp. Med., 2003-01-06;197(1):121-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Regulation of the interleukin-5 receptor alpha-subunit on peripheral blood eosinophils from healthy subjects.
Authors: Hellman C, 107334, Hallden G, Hylander B, Lundahl J
Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling, 2003-01-01;131(1):75-81.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Prospective isolation of human clonogenic common myeloid progenitors.
Authors: Manz MG, 107325, Miyamoto T, Akashi K, Weissman IL
Ultra-Sensitive and Semi-Quantitative Vertical Flow Assay for the Rapid Detection of Interleukin-6 in Inflammatory Diseases, 2002-08-22;99(18):11872-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Eosinophils express functional IL-13 in eosinophilic inflammatory diseases.
Authors: Schmid-Grendelmeier P, Altznauer F, Fischer B, Bizer C, Straumann A, Menz G, Blaser K, Wuthrich B, Simon HU
J. Immunol., 2002-07-15;169(2):1021-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells.
Authors: Edgeworth JD, Spencer J, Phalipon A, Griffin GE, Sansonetti PJ
Eur. J. Immunol., 2002-05-01;32(5):1464-71.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN.
Authors: Wu L, 107253, Bashirova AA, Martin TD, Villamide L, Mehlhop E, Chertov AO, Unutmaz D, Pope M, Carrington M, KewalRamani VN
IL-6 signalling biomarkers in hospitalised patients with moderate to severe SARS-CoV-2 infection in a single centre study in Sweden, 2002-01-29;99(3):1568-73.
Species: Human, Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay -
A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells.
Authors: Shih CC, Hu MC, Hu J
Blood, 2000-03-15;95(6):1957-66.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver.
Authors: Barcena A, Park SW, Banapour B, Muench MO, Mechetner E
Blood, 1996-09-15;88(6):2013-25.
Species: Human
Sample Types:
Applications: Bioassay
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Average Rating: 4.7 (Based on 15 Reviews)
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Reason for Rating: worked well with cell culture
Reason for Rating: Used for macrophage plating and differentiation from human PBMCs. Worked consistently well
Used for differentiation of CD11c+ DCs from PBMC derived CD14+ monocytes
Reason for Rating: GM-CSF effectively differentiated primary monocytes to M1 macrophages
Reason for Rating: Dendritic cell generation was always consistent with this product
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