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(R)-(+)-Blebbistatin

Catalog #: 1853
3 Citations Datasheet / COA / SDS

Discontinued Product

1853 has been discontinued.
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(R)-(+)-Blebbistatin | CAS No. 1177356-70-5 | Myosin Inhibitors
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Description: Selective inhibitor of myosin II ATPase activity. Inactive enantiomer of (±)-blebbistatin (Cat. No. 1760)

Chemical Name: (3aR)-(+)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one

Purity: ≥99%

Product Details
Citations (3)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

(R)-(+)-Blebbistatin is an inactive enantiomer of the selective inhibitor of myosin II (±)-blebbistatin.

Active Enantiomer and Racemate also available.

Technical Data

M.Wt:
292.34
Formula:
C18H16N2O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
1177356-70-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. Specificity of blebbistatin, an inhibitor of myosin II.
    Limouze et al.
    J.Muscle Res.Cell Motil., 2004;25:337
  2. Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor.
    Straight et al.
    Science, 2003;299:1743
  3. Dissecting cytokinesis with small molecules.
    Straight et al.
    Amer.Soc.Cell Biol.Abstr., 2002;:2515

Product Datasheets

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Citations for (R)-(+)-Blebbistatin

The citations listed below are publications that use Tocris products. Selected citations for (R)-(+)-Blebbistatin include:

3 Citations: Showing 1 - 3

  1. Real-time two- and three-dimensional imaging of monocyte motility and navigation on planar surfaces and in collagen matrices: roles of Rho.
    Authors: Bzymek Et al.
    Sci Rep  2016;6:25016
  2. Asymmetric division of contractile domains couples cell positioning and fate specification.
    Authors: Ma?tre Et al.
    Nature  2016;536:344
  3. A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation.
    Authors: Nyholm Et al.
    J Cell Sci  2009;122:2137

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