Quizartinib

Catalog # Availability Size / Price Qty
6788/10
6788/50
Quizartinib | CAS No. 950769-58-1 | Flt-3 Inhibitors
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Description: Highly potent FLT3 inhibitor

Chemical Name: N-[5-(1,1-Dimethylethyl)-3-isoxazolyl]-N'-[4-[7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b]benzothiazol-2-yl]phenyl]urea

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Quizartinib is a highly potent FMS-like receptor tyrosine kinase-3 (FLT3) inhibitor (Kd = 1.6 nM, IC50 = 0.56 nM in MV4-11 cell proliferation assay). Displays >10-fold selectivity for FLT3 over panel of 400 kinases. Inhibits FLT3 activity and displays antitumor properties in a mouse MV4-11 tumor xenograft model.

Technical Data

M.Wt:
560.67
Formula:
C29H32N6O4S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
950769-58-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for Quizartinib

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