Prosaptide TX14(A)

Catalog #: 5151 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
5151/1

1 Image

Description: Potent GPR37 and GPR37L1 agonist

Purity: ≥95%

View All Products for Orphan 7-TM Receptor Agonists

Product Details

Supplemental Products

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Prosaptide TX14(A) is a potent GPR37L1 and GPR37 agonist (EC₅₀ values are 5 and 7 nM, respectively). Stimulates signaling through pertussis toxin-sensitive G proteins. Stimulates ERK phosphorylation. Protects against cellular stress. Promotes myelin lipid synthesis and prolongs cell survival in both Schwann cells and oligodendrocytes; neuroprotective and glioprotective.

Technical Data

M.Wt:

1579.72

Formula:

C₆₉H₁₁0N₁₆O₂₆

Sequence:

TALIDNNATEEILY

(Modification: Ala-2 = D-Ala)

Solubility:

Soluble to 2 mg/ml in water

Purity:

≥95%

Storage:

Store at -20°C

CAS No:

196391-82-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Cell death prevention, mitogen-activated protein kinase stimulation, and increased sulfatide concentrations in Schwann cells and oligodendrocytes by prosaposin and prosaptides.
Hiraiwa et al.
Proc.Natl.Acad.Sci.USA., 1997;94:4778
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.
Meyer et al.
Proc.Natl.Acad.Sci.USA., 2013;110:9529

Product Datasheets

COA view current batch

Or select another batch:

View Batch

SDS

Reconstitution Calculator

Molarity Calculator

Reconstitution Calculator

Molarity Calculator

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

Reviews for Prosaptide TX14(A)

There are currently no reviews for this product. Be the first to review Prosaptide TX14(A) and earn rewards!

Have you used Prosaptide TX14(A)?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.