PEN (mouse)

Catalog #: 6308 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
6308/1

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Description: GPR83 agonist

Alternative Names: pro-SAAS (221-242)

Purity: ≥95%

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Biological Activity

PEN (mouse) is a endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide. Activates phospholipase C (PLC)-mediated signaling cascade in mouse hypothalamus.

Technical Data

M.Wt:

2317.62

Formula:

C₁₀₂H₁₆₉N₂₇O₃₄

Sequence:

SVDQDLGPEVPPENVLGALLRV

Solubility:

Soluble to 1 mg/ml in PBS (pH 7.4)

Purity:

≥95%

Storage:

Store at -20°C

CAS No:

1236955-25-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Identification of GPR83 as the receptor for the neuroendocrine peptide PEN.
Gomes et al.
Sci.Signal, 2016;9:ra43
Neuropeptide PEN and its receptor GPR83: distribution, signaling, and regulation.
Mack et al.
ACS Chem.Neurosci., 2019;10:1884

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