pCPA methyl ester hydrochloride

Catalog #: 5871 Datasheet / COA / SDS

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pCPA methyl ester hydrochloride | CAS No. 14173-40-1 | Hydroxylase Inhibitors

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Description: Tryptophan hydroxylase inhibitor

Chemical Name: 4-Chloro-DL-Phenylalanine methyl ester hydrochloride

Purity: ≥98%

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Biological Activity

pCPA methyl ester hydrochloride is a tryptophan hydroxylase inhibitor. Inhibits 5-HT synthesis. Depletes 5-HT levels in orbitofrontal cortex and impairs reversal learning in rats. Methyl ester of p-Chlorophenylalanine (Cat. No. 0938).

Technical Data

M.Wt:

250.12

Formula:

C₁₀H₁₂ClNO₂.HCl

Solubility:

Soluble to 100 mM in water and to 100 mM in DMSO

Purity:

≥98%

Storage:

Store at -20°C

CAS No:

14173-40-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test.
Pinto Brod et al.
Prog.Neuropsychopharmacol.Biol.Psychiatry., 2016;65:201
Vort. restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats.
Wallace et al.
Int.J.Neuropsychopharmacol., 2014;17:1695

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