ONO 8130
Chemical Name: 4-[[[2,3-Dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-indene-5yl]oxy]methyl]benzoic acid
Purity: ≥98%
Biological Activity
ONO 8130 is an EP1 receptor antagonist. Exhibits analgesic effect in a mouse model of cystitis. Orally bioavailable.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
ONO-8130, a selective prostanoid EP1 receptor antagonist, relieves bladder pain in mice with cyclophosphamide-induced cystitis.
Miki et al.
Pain, 2011;152:1373 -
Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to cloz. in mouse models of schizophrenia.
Lipina et al.
Psychopharmacology, 2005;179:54
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for ONO 8130
The citations listed below are publications that use Tocris products. Selected citations for ONO 8130 include:
1 Citation: Showing 1 - 1
-
NR5A2/LRH-1 regulates the PTGS2-PGE2-PTGER1 pathway contributing to pancreatic islet survival and function.
Authors: Petra I Et al.
iScience 2022;25:104345
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for ONO 8130
Average Rating: 3 (Based on 1 Review)
Have you used ONO 8130?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Filter by:
