Nafamostat mesylate

Catalog # Availability Size / Price Qty
3081/10
3081/50
Nafamostat mesylate | CAS No. 82956-11-4 | TMPRSS2 Inhibitors
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Description: Serine protease inhibitor; inhibits tryptase

Chemical Name: 4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity

Nafamostat mesylate is a broad spectrum serine protease inhibitor. Displays selectivity for human tryptase when used at relatively low concentrations. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. Inhibits SARS-CoV-2 infection in vitro (EC50 = 22.50 μM).

Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

Technical Data

M.Wt:
539.59
Formula:
C19H17N5O2.2CH4O3S
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
82956-11-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for Nafamostat mesylate

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