N¹,N¹²-Diethylspermine tetrahydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Synthetic polyamine analogues as antineoplastics.
   Bergeron et al.
   J.Med.Chem., 1988;31:1183
2. Synthesis and bioloigcal evaluation of aminopolyamines.
   Bergeron et al.
   J.Med.Chem., 2005;48:3099
3. Combined regulation of arginine and S-adenosylmethionine decarboxylases by spermine and the spermine analogue N¹,N¹²-bis(ethyl)spermine.
   Porter et al.
   Biochem.J., 1990;268:207
4. Selective cellular depletion of mitochondrial DNA by the polyamine analog N¹,N¹²-bis(ethyl)spermine and its relationship to polyamine structure and function.
   Vertino et al.
   Mol.Pharmacol., 1991;39:487

Product Datasheets