Mouse Vitronectin Antibody Summary
Asp20-Lys478
Accession # AAH12690
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
![Vitronectin antibody in Mouse Brain by Immunohistochemistry (IHC-Fr). Vitronectin antibody in Mouse Brain by Immunohistochemistry (IHC-Fr).](https://resources.rndsystems.com/images/datasheets/antibody/Vitronectin_MAB38751_Immunohistochemistry_7011.jpg)
Vitronectin in Mouse Brain. Vitronectin was detected in immersion fixed frozen sections of fetal mouse brain using 10 µg/mL Rat Anti-Mouse Vitronectin Monoclonal Antibody (Catalog # MAB38751) overnight at 4 °C. Tissue was stained with the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI (blue). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Vitronectin
Vitronectin is a 71 kDa secreted glycoprotein produced by the liver and tumor cells. In blood, Vitronectin is called serum spreading factor. In the extracellular matrix, its function is determined by binding partners such as PAI-1, complement factors, integrins (notably alpha v beta 3) and thrombin. The 459 amino acid (aa) mature mouse Vitronectin shows 74% aa sequence identity with human Vitronectin and contains somatomedin B-like and hemopexin-like domains, an RGD motif, a basic heparin-binding domain and sulfated tyrosines. Unbound Vitronectin is a monomer that may be cleaved to form a dimer of 65 kDa and 10 kDa components.
Product Datasheets
Citations for Mouse Vitronectin Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 8
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Suppression of CEBPdelta recovers exhaustion in anti-metastatic immune cells
Authors: C Yin, M Kato, T Tomita, Y Han, S Hiratsuka
Scientific Reports, 2023-03-08;13(1):3903.
Species: Mouse
Sample Types: Whole Tissue
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Precapillary sphincters maintain perfusion in the cerebral cortex
Authors: S Grubb, C Cai, BO Hald, L Khennouf, RP Murmu, AGK Jensen, J Fordsmann, S Zambach, M Lauritzen
Nat Commun, 2020-01-20;11(1):395.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvessels
Authors: Z Bagi, Y Couch, Z Broskova, F Perez-Bald, T Yeo, S Davis, R Fischer, NR Sibson, BG Davis, DC Anthony
Sci Rep, 2019-11-01;9(1):15847.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Hepato-entrained B220+CD11c+NK1.1+ cells regulate pre-metastatic niche formation in the�lung
Authors: S Hiratsuka, T Tomita, T Mishima, Y Matsunaga, T Omori, S Ishibashi, S Yamaguchi, T Hosogane, H Watarai, M Omori-Miya, T Yamamoto, N Shibata, A Watanabe, H Aburatani, M Tomura, KA High, Y Maru
EMBO Mol Med, 2018-07-01;10(7):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Multicolor quantitative confocal imaging cytometry
Authors: DL Coutu, KD Kokkaliari, L Kunz, T Schroeder
Nat. Methods, 2017-11-13;15(1):39-46.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Integrin-mediated interactions between B cells and follicular dendritic cells influence germinal center B cell fitness.
Authors: Wang X, Rodda L, Bannard O, Cyster J
J Immunol, 2014-04-16;192(10):4601-9.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression.
Authors: Franco M, Roswall P, Cortez E, Hanahan D, Pietras K
Blood, 2011-07-21;118(10):2906-17.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
Age-related retinopathy in NRF2-deficient mice.
Authors: Zhao Z, Chen Y, Wang J
PLoS ONE, 2011-04-29;6(4):e19456.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr
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