Mouse IL-31 Antibody

Catalog #: AF3028
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3028
AF3028-SP

All IL-31 Antibodies

Product Details

Citations (1)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse IL-31 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse IL-31 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human IL-31 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse IL-31
Thr24-Cys163
Accession # Q6EAL8

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse IL‑31

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-31

IL-31 is a 25 kDa, unique member of the short chain group of alpha -helical cytokines. It is produced by activated T cells, particularly the Th2 CD4⁺ phenotype. Mouse IL‑31 cDNA encodes a 163 amino acid (aa) precursor that contains a 22 aa signal sequence and a 141 aa mature region. IL-31 signals through a receptor complex composed of IL-31 receptor A and Oncostatin M receptor. Mature mouse IL‑31 shares 25% aa sequence identity with mature human IL-31 and 44% aa sequence identity with a rat IL-31-like protein.

Long Name

Interleukin 31

Entrez Gene IDs

386653 (Human); 76399 (Mouse)

Alternate Names

IL31; IL-31; IL-31interleukin-31; interleukin 31

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse IL-31 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31.
Authors: Shen M, Siu S, Byrd S, Edelmann KH, Patel N, Ketchem RR, Mehlin C, Arnett HA, Hasegawa H
Exp. Cell Res., 2010-12-21;317(7):976-93.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot