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Mouse IFN-alpha Fluorescein MAb (Clone RMMA-1)

Catalog #: 22100-3
3 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
22100-3
Product Details
Citations (3)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse IFN-alpha Fluorescein MAb (Clone RMMA-1) Summary

Source
Monoclonal Rat IgG1 Clone # RMMA-1
Formulation
Phosphate buffered saline (PBS) containing 1% BSA and 0.05% Kathon, pH 7.2
Label
Fluorescein (Excitation= 488 nm, Emission= 515-545 nm)
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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Long Name
Interferon alpha
Entrez Gene IDs
3440 (Human)
Alternate Names
IFNA; IFNA2; IFNA2b; IFNalpha; IFN-alpha; IFN-alphaA; INFA2; interferon alpha 2; LeIF D

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Citations for Mouse IFN-alpha Fluorescein MAb (Clone RMMA-1)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. Alcohol enhances type 1 interferon-? production and mortality in young mice infected with Mycobacterium tuberculosis
    Authors: D Tripathi, E Welch, SS Cheekatla, RK Radhakrish, S Venkatasub, P Paidipally, A Van, B Samten, KP Devalraju, VSK Neela, VL Valluri, C Mason, S Nelson, R Vankayalap
    PLoS Pathog., 2018-08-02;14(8):e1007174.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
    Authors: Lena M Kranz
    Nature, 2016-06-01;534(7607):396-401.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. Type I IFNs Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-versus-Host Disease
    J Immunol, 2016-05-25;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr

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