Mouse DCIR/CLEC4A PE-conjugated Antibody

Catalog #: FAB26171P
1 Citation Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB26171P

Detection of DCIR/CLEC4A in Mouse Dendritic cells by Flow Cytometry.

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All DCIR/CLEC4A Antibodies

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Citations (1)

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Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse DCIR/CLEC4A PE-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse DCIR/CLEC4A in direct ELISAs.

Source

Monoclonal Rat IgG_2A Clone # 320507

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse DCIR/CLEC4A isoform 1
Gln70-Leu238
Accession # Q9QZ15

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of DCIR/CLEC4A in Mouse Dendritic cells by Flow Cytometry. Mouse bone marrow-derived dendritic cells were stained with Rat Anti-Mouse DCIR/CLEC4A PE-conjugated Monoclonal Antibody (Catalog # FAB26171P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Flow Cytometry

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Detection of DCIR/CLEC4A in Mouse Bone Marrow cells by Flow Cytometry. Mouse bone marrow cells were stained with Rat Anti-Mouse DCIR/CLEC4A PE-conjugated Monoclonal Antibody (Catalog # FAB26171P, filled histogram) or isotype control antibody (IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: DCIR/CLEC4A

DCIR (Dendritic Cell Immunoreceptor), also known as LLIR (Lectin-Like Immunoreceptor), is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM) in its cytoplasmic domain. Besides DC, DCIR is expressed on B cells, monocytes/macrophages and granulocytes.

Long Name

Dendritic Cell Immunoreceptor

Entrez Gene IDs

50856 (Human); 26888 (Mouse)

Alternate Names

CD367; CLEC4A; CLECSF6; CLECSF6C-type lectin superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; DCIR; DCIRLLIR; DDB27; DDB27C-type lectin DDB27; Dendritic cell immunoreceptor; Lectin-like immunoreceptor; LLIR

Product Datasheets

Product Datasheet

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Related Research Areas

Citation for Mouse DCIR/CLEC4A PE-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Dendritic cell immunoreceptor regulates Chikungunya virus pathogenesis in mice.
Authors: Long, Kristin, Whitmore, Alan C, Ferris, Martin T, Sempowski, Gregory, McGee, Charles, Trollinger, Bianca, Gunn, Bronwyn, Heise, Mark T
J Virol, 2013-03-13;87(10):5697-706.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry