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Mouse CD45 Antibody

Catalog #: AF114
68 Citations 2 Reviews Datasheet / COA / SDS
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AF114
AF114-SP
CD45 in RAW 264.7 Mouse Cell Line.
3 Images
Product Details
Citations (68)
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Supplemental Products
Reviews (2)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse CD45 Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse CD45 in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse CD45
Gln24-Lys425
Accession # NP_035340
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse CD45 (Catalog # 114-CD)
Flow Cytometry
2.5 µg/106 cells
Mouse splenocytes
Immunohistochemistry
3-15 µg/mL
See below
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 
Immunocytochemistry
5-15 µg/mL
Immersion fixed mouse splenocytes

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunocytochemistry View Larger

CD45 in RAW 264.7 Mouse Cell Line. CD45 was detected in immersion fixed RAW 264.7 mouse monocyte/macrophage cell line (positive staining) and Neuro‑2A mouse neuroblastoma cell line (negative staining) using Goat Anti-Mouse CD45 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF114) at 5 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to cell surface. Staining was performed using our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Immunohistochemistry CD45 antibody in Mouse Liver by Immunohistochemistry (IHC-P). View Larger

CD45 in Mouse Liver. CD45 was detected in immersion fixed paraffin-embedded sections of mouse liver using Goat Anti-Mouse CD45 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF114) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to Kupffer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD45 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD45 by Immunocytochemistry/Immunofluorescence The recruitment of CD45+F4/80+CD68+ macrophages was similar in the ASC-seeded DAT scaffolds that were cultured dynamically and statically for 14 days prior to implantation in the nu/nu mouse model. (A) Representative images showing CD45 (cyan), F4/80 (red), and CD68 (green) expression with DAPI counterstaining (blue) at 1-week post-implantation. Scale bars represent 100 μm. Boxed regions in the composite images are shown at higher magnification below. White arrowheads highlight CD45+F4/80+CD68+DAPI+ cells. (B) CD45+F4/80+CD68+DAPI+ cell density in the static and dynamic groups. (C) The percentage of CD45+F4/80+CD68+DAPI+ cells relative to the total CD45+DAPI+ cell population at 1, 4, and 8 weeks. *p < 0.05, **p < 0.01, ***p < 0.001. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33816453), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CD45

Mouse CD45 (also known as Ly5 and leukocyte common antigen) is a 180‑220 kDa variably glycosylated member of the class 1 subtype of the protein tyrosine phosphatase family. It is synthesized as a 1291 amino acid (aa) precursor that contains a 23 aa signal sequence, a 541 aa extracellular domain (ECD), a 22 aa transmembrane segment, and a 705 aa cytoplasmic region. The ECD is coded for by exons 4‑16 of the CD45 gene. Alternate splicing of exon 4 (or A) (aa 30‑74), exon 5 (or B) (aa 75‑123) and exon 6 (or C) (aa 124‑169) define different lymphocyte populations and functional stages. Naïve T cells express exon 5 (CD45 RB), while activated T cells express neither exon 4, 5 or 6 (CD 45 RO). B cells express CD45 RABC, while resting NK cells express CD45 RA. Mouse CD45 ECD shares 60% and 44% aa sequence identity with rat and human full‑length CD45 ECD, respectively.

Long Name
Cluster of Differentiation 45
Entrez Gene IDs
5788 (Human); 19264 (Mouse); 490255 (Canine); 100061950 (Equine)
Alternate Names
B220; CD_antigen: CD45; CD45 antigen; CD45; CD45R; EC 3.1.3.48; EC:3.1.3.48; GP180; LCA; L-CA; Leukocyte common antigen; LY5; protein tyrosine phosphatase, receptor type, c polypeptide; PTPRC; receptor-type tyrosine-protein phosphatase C; T200 Glycoprotein; T200 leukocyte common antigen; T200

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Citations for Mouse CD45 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

68 Citations: Showing 1 - 10
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  1. Heterogeneity in macrophages along the cochlear spiral in mice: insights from SEM and functional analyses
    Authors: Celia Zhang, Mengxiao Ye, Peter Bush, Bo Hua Hu
    Frontiers in Cellular Neuroscience
  2. RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis.
    Authors: Yu M, Ting DT, Stott SL et al.
    Nature
  3. IL-17-induced HIF1? drives resistance to anti-PD-L1 via fibroblast-mediated immune exclusion
    Authors: Chen X, Zhao J, Herjan T et al.
    Journal of Experimental Medicine
  4. Bacterial meningitis in the early postnatal mouse studied at single-cell resolution
    Authors: Wang J, Rattner A, Nathans J
    eLife
  5. A Milieu Molecule for TGF-beta Required for Microglia Function in the Nervous System
    Authors: Yan Qin, Brian S. Garrison, Wenjiang Ma, Rui Wang, Aiping Jiang, Jing Li et al.
    Cell
  6. Inhibition of fibronectin polymerization alleviates kidney injury due to ischemia-reperfusion
    Authors: Stephanie L. K. Bowers, Stephanie Davis-Rodriguez, Zachary M. Thomas, Valeria Rudomanova, W. Clark Bacon, Alex Beiersdorfer et al.
    American Journal of Physiology-Renal Physiology
  7. Therapeutic activation of endothelial sphingosine‐1‐phosphate receptor 1 by chaperone‐bound S1P suppresses proliferative retinal neovascularization
    Authors: Colin Niaudet, Bongnam Jung, Andrew Kuo, Steven Swendeman, Edward Bull, Takahiro Seno et al.
    EMBO Molecular Medicine
  8. Combining three independent pathological stressors induces a heart failure with preserved ejection fraction phenotype
    Authors: Li Y, Kubo H, Yu D et al.
    American journal of physiology. Heart and circulatory physiology
  9. Inflammation and neutrophil extracellular traps in cerebral cavernous malformation
    Authors: Anthony C. Y. Yau, Maria Ascencion Globisch, Favour Chinyere Onyeogaziri, Lei L. Conze, Ross Smith, Suvi Jauhiainen et al.
    Cellular and Molecular Life Sciences
  10. Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury
    Authors: Jing Liu, Sanjeev Kumar, Andreas Heinzel, Michael Gao, Jinjin Guo, Gregory F. Alvarado et al.
    Journal of the American Society of Nephrology
  11. Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis
    Authors: Ghoshal, A;Rodrigues, LC;Gowda, CP;Elcheva, IA;Liu, Z;Abraham, T;Spiegelman, VS;
    Oncogene
  12. Oseltamivir (Tamiflu), a Commonly Prescribed Antiviral Drug, Mitigates Hearing Loss in Mice
    Authors: Sailor-Longsworth, E;Lutze, RD;Ingersoll, MA;Kelmann, RG;Ly, K;Currier, D;Chen, T;Zuo, J;Teitz, T;
    bioRxiv : the preprint server for biology
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  13. mTORC1 hyperactivation and resultant suppression of macroautophagy contribute to the induction of cardiomyocyte necroptosis by catecholamine surges
    Authors: Cai, M;Wu, P;Ni, W;Huang, D;Wang, X;
    Physiological reports
    Species: Rat
    Sample Types: Cell Lysates
    Applications: Western Blot
  14. Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo
    Authors: Gonzalez Galofre, ZN;Kilpatrick, AM;Marques, M;Sá da Bandeira, D;Ventura, T;Gomez Salazar, M;Bouilleau, L;Marc, Y;Barbosa, AB;Rossi, F;Beltran, M;van de Werken, HJG;van IJcken, WFJ;Henderson, NC;Forbes, SJ;Crisan, M;
    Nature communications
    Species: Mouse
    Sample Types: Embryo
    Applications: IHC
  15. Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors
    Authors: Shojaie, L;Bogdanov, JM;Alavifard, H;Mohamed, MG;Baktash, A;Ali, M;Mahov, S;Murray, S;Kanel, GC;Liu, ZX;Ito, F;In, GK;Merchant, A;Stohl, W;Dara, L;
    Cell death & disease
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  16. Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments
    Authors: Abraham, MJ;Goncalves, C;McCallum, P;Gupta, V;Preston, SEJ;Huang, F;Chou, H;Gagnon, N;Johnson, NA;Miller, WH;Mann, KK;Del Rincon, SV;
    Cell & bioscience
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  17. Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB
    Authors: Zhou, LY;Jin, CX;Wang, WX;Song, L;Shin, JB;Du, TT;Wu, H;
    eLife
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: ICC
  18. Cellular iron governs the host response to malaria
    Authors: Wideman, SK;Frost, JN;Richter, FC;Naylor, C;Lopes, JM;Viveiros, N;Teh, MR;Preston, AE;White, N;Yusuf, S;Draper, SJ;Armitage, AE;Duarte, TL;Drakesmith, H;
    PLoS pathogens
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  19. Topical formulations of Aprepitant are safe and effective in relieving pain and inflammation, and drive neural regeneration
    Authors: Bonelli, F;Demirsoy, I;Lasagni Vitar, RM;Fonteyne, P;Ferrari, G;
    The ocular surface
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  20. The cGAS-STING pathway is dispensable in a mouse model of LMNA -cardiomyopathy despite nuclear envelope rupture
    Authors: En, A;Bogireddi, H;Thomas, B;Stutzman, A;Ikegami, S;LaForest, B;Almakki, O;Pytel, P;Moskowitz, IP;Ikegami, K;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  21. Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation
    Authors: Zhang, T;Xu, D;Liu, J;Wang, M;Duan, LJ;Liu, M;Meng, H;Zhuang, Y;Wang, H;Wang, Y;Lv, M;Zhang, Z;Hu, J;Shi, L;Guo, R;Xie, X;Liu, H;Erickson, E;Wang, Y;Yu, W;Dang, F;Guan, D;Jiang, C;Dai, X;Inuzuka, H;Yan, P;Wang, J;Babuta, M;Lian, G;Tu, Z;Miao, J;Szabo, G;Fong, GH;Karnoub, AE;Lee, YR;Pan, L;Kaelin, WG;Yuan, J;Wei, W;
    Nature cell biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  22. SEC-seq: association of molecular signatures with antibody secretion in thousands of single human plasma cells
    Authors: Cheng, RY;de Rutte, J;Ito, CEK;Ott, AR;Bosler, L;Kuo, WY;Liang, J;Hall, BE;Rawlings, DJ;Di Carlo, D;James, RG;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Capture
  23. Antibody-Mediated Delivery of VEGF-C Promotes Long-Lasting Lymphatic Expansion That Reduces Recurrent Inflammation
    Authors: N Cousin, S Bartel, J Scholl, C Tacconi, A Egger, G Thorhallsd, D Neri, LC Dieterich, M Detmar
    Cells, 2022-12-31;12(1):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  24. Chronic suppurative otitis media causes macrophage-associated sensorineural hearing loss
    Authors: A Xia, A Thai, Z Cao, X Chen, J Chen, B Bacacao, LA Bekale, V Schiel, PL Bollyky, PLS Maria
    Journal of Neuroinflammation, 2022-09-12;19(1):224.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  25. The protective effects of systemic dexamethasone on sensory epithelial damage and hearing loss in targeted Cx26-null mice
    Authors: K Xu, S Chen, L Xie, Y Qiu, XZ Liu, X Bai, Y Jin, XH Wang, Y Sun
    Cell Death & Disease, 2022-06-10;13(6):545.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  26. Diabetes impairs cardioprotective function of endothelial progenitor cell-derived extracellular vesicles via H3K9Ac inhibition
    Authors: G Huang, Z Cheng, A Hildebrand, C Wang, M Cimini, R Roy, AM Lucchese, C Benedict, V Mallaredy, A Magadum, D Joladarash, C Thej, C Gonzalez, M Trungcao, VNS Garikipati, JW Elrod, WJ Koch, R Kishore
    Theranostics, 2022-05-21;12(9):4415-4430.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  27. Dose and Dose Rate-Dependent Effects of Low-Dose Irradiation on Inflammatory Parameters in ApoE-Deficient and Wild Type Mice
    Authors: A Glasow, I Patties, ND Priest, REJ Mitchel, G Hildebrand, K Manda
    Cells, 2021-11-20;10(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  28. A transcriptome atlas of the mouse iris at single-cell resolution defines cell types and the genomic response to pupil dilation
    Authors: J Wang, A Rattner, J Nathans
    Elife, 2021-11-16;10(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  29. Nociceptive sensory neurons promote CD8 T cell responses to HSV-1 infection
    Authors: J Filtjens, A Roger, L Quatrini, E Wieduwild, J Gouilly, G Hoeffel, R Rossignol, C Daher, G Debroas, S Henri, CM Jones, B Malissen, LK Mackay, A Moqrich, FR Carbone, S Ugolini
    Nature Communications, 2021-05-18;12(1):2936.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  30. Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model
    Authors: SS Qin, BJ Han, A Williams, KM Jackson, R Jewell, AC Chacon, EM Lord, DC Linehan, M Kim, A Reuben, SA Gerber, PA Prieto
    Cancers, 2021-05-11;13(10):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  31. Modulating Ocular Surface Pain Through Neurokinin-1 Receptor Blockade
    Authors: RM Lasagni Vi, M Barbariga, P Fonteyne, F Bignami, P Rama, G Ferrari
    Investigative Ophthalmology & Visual Science, 2021-03-01;62(3):26.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  32. Airway-Associated Macrophages in Homeostasis and Repair
    Authors: AE Engler, AB Ysasi, RMF Pihl, C Villacorta, HM Heston, HMK Richardson, BR Thapa, NR Moniz, AC Belkina, SA Mazzilli, JR Rock
    Cell Reports, 2020-12-29;33(13):108553.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  33. Sectoral activation of glia in an inducible mouse model of autosomal dominant retinitis pigmentosa
    Authors: MT Massengill, NF Ash, BM Young, CJ Ildefonso, AS Lewin
    Sci Rep, 2020-10-12;10(1):16967.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  34. The immune response after noise damage in the cochlea is characterized by a heterogeneous mix of adaptive and innate immune cells
    Authors: V Rai, MB Wood, H Feng, NM Schabla, S Tu, J Zuo
    Scientific Reports, 2020-09-16;10(1):15167.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  35. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm
    Authors: SJ Jeong, MJ Cho, NY Ko, S Kim, IH Jung, JK Min, SH Lee, JG Park, GT Oh
    Exp. Mol. Med., 2020-09-14;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  36. Keratinocyte-Expressed Podoplanin is Dispensable for Multi-Step Skin Carcinogenesis
    Authors: M Sesarti?, K Ikenberg, SY Yoon, M Detmar
    Cells, 2020-06-24;9(6):.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  37. FAM19A5 Expression During Embryogenesis and in the Adult Traumatic Brain of FAM19A5-LacZ Knock-in Mice
    Authors: A Shahapal, EB Cho, HJ Yong, I Jeong, H Kwak, JK Lee, W Kim, B Kim, HC Park, WS Lee, H Kim, JI Hwang, JY Seong
    Front Neurosci, 2019-08-30;13(0):917.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  38. Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation
    Authors: S Schwager, S Renner, T Hemmerle, S Karaman, ST Proulx, R Fetz, AM Golding-Oc, P Probst, C Halin, D Neri, M Detmar
    JCI Insight, 2018-12-06;3(23):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  39. STAT5A/B BLOCKADE SENSITIZES PROSTATE CANCER TO RADIATION THROUGH INHIBITION OF RAD51 AND DNA REPAIR
    Authors: C Maranto, V Udhane, DT Hoang, L Gu, V Alexeev, KM Malas, K Cardenas, JR Brody, U Rodeck, C Bergom, KA Iczkowski, K Jacobsohn, WA See, SM Schmitt, MT Nevalainen
    Clin. Cancer Res., 2018-02-26;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  40. Type I interferons instigate fetal demise after Zika virus infection
    Authors: LJ Yockey, KA Jurado, N Arora, A Millet, T Rakib, KM Milano, AK Hastings, E Fikrig, Y Kong, TL Horvath, S Weatherbee, HJ Kliman, CB Coyne, A Iwasaki
    Sci Immunol, 2018-01-05;3(19):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  41. Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion
    Authors: J Liu, S Kumar, E Dolzhenko, GF Alvarado, J Guo, C Lu, Y Chen, M Li, MC Dessing, RK Parvez, PE Cippà, AM Krautzberg, G Saribekyan, AD Smith, AP McMahon
    JCI Insight, 2017-09-21;2(18):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  42. Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss
    Authors: MX Hernandez, S Jiang, TA Cole, SH Chu, MI Fonseca, MJ Fang, LA Hohsfield, MD Torres, KN Green, RA Wetsel, A Mortazavi, AJ Tenner
    Mol Neurodegener, 2017-09-18;12(1):66.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  43. Metabolic origins of spatial organization in the tumor microenvironment
    Authors: C Carmona-Fo, M Deforet, L Akkari, CB Thompson, JA Joyce, JB Xavier
    Proc. Natl. Acad. Sci. U.S.A, 2017-02-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  44. Immunization with Bacillus Calmette-Gu�rin (BCG) alleviates neuroinflammation and cognitive deficits in APP/PS1 mice via the recruitment of inflammation-resolving monocytes to the brain
    Authors: Z Zuo, F Qi, J Yang, X Wang, Y Wu, Y Wen, Q Yuan, J Zou, K Guo, ZB Yao
    Neurobiol. Dis, 2017-02-09;101(0):27-39.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  45. CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis
    Authors: Jong-Gil Park
    Sci Rep, 2016-06-15;6(0):27938.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  46. Low-dose irradiation affects expression of inflammatory markers in the heart of ApoE -/- mice.
    Authors: Mathias D, Mitchel R, Barclay M, Wyatt H, Bugden M, Priest N, Whitman S, Scholz M, Hildebrandt G, Kamprad M, Glasow A
    PLoS ONE, 2015-03-23;10(3):e0119661.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  47. Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this.
    Authors: Liakhovitskaia A, Rybtsov S, Smith T, Batsivari A, Rybtsova N, Rode C, de Bruijn M, Buchholz F, Gordon-Keylock S, Zhao S, Medvinsky A
    Development, 2014-09-01;141(17):3319-23.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  48. Downstream Toll-like receptor signaling mediates adaptor-specific cytokine expression following focal cerebral ischemia.
    J Neuroinflammation, 2012-07-16;9(0):174.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  49. Serine protease inhibition reduces post-ischemic granulocyte recruitment in mouse intestine.
    Authors: Gobbetti T, Cenac N, Motta JP, Rolland C, Martin L, Andrade-Gordon P, Steinhoff M, Barocelli E, Vergnolle N
    Am. J. Pathol., 2011-11-07;180(1):141-52.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  50. Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling.
    Authors: Arora D, Stopp S, Bohmer SA, Schons J, Godfrey R, Masson K, Razumovskaya E, Ronnstrand L, Tanzer S, Bauer R, Bohmer FD, Muller JP
    J. Biol. Chem., 2011-01-24;286(13):10918-29.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  51. Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha.
    Authors: Kraman M, Bambrough P, Arnold J, Roberts E, Magiera L, Jones J, Gopinathan A, Tuveson D, Fearon D
    Science, 2010-11-05;330(6005):827-30.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  52. Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling.
    Authors: Graham BB, Mentink-Kane MM, El-Haddad H
    Am. J. Pathol., 2010-07-29;177(3):1549-61.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  53. Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells.
    Authors: Chou S, Lodish HF
    Proc. Natl. Acad. Sci. U.S.A., 2010-04-12;107(17):7799-804.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  54. FGF2-dependent neovascularization of subcutaneous Matrigel plugs is initiated by bone marrow-derived pericytes and macrophages.
    Authors: Tigges U, Hyer EG, Scharf J, Stallcup WB
    Development, 2008-01-02;135(3):523-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  55. IL-12 alpha deficiency attenuates pressure overload-induced cardiac inflammation, hypertrophy, dysfunction, and heart failure progression
    Authors: Umesh Bhattarai, Xiaochen He, Rui Xu, Xiaoguang Liu, Lihong Pan, Yuxiang Sun et al.
    Frontiers in Immunology
  56. Promotion of Lymphangiogenesis by Targeted Delivery of VEGF-C Improves Diabetic Wound Healing
    Authors: LM Brunner, Y He, N Cousin, J Scholl, LK Albin, B Schmucki, S Supersaxo, G Restivo, J Hafner, D Neri, S Werner, M Detmar
    Cells, 2023-02-01;12(3):.
  57. Automated segmentation and analysis of retinal microglia within ImageJ
    Authors: Neil F. Ash, Michael T. Massengill, Lindsey Harmer, Ahmed Jafri, Alfred S. Lewin
    Experimental Eye Research
  58. Tgf?1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury
    Authors: Nordquist EM, Dutta P, Kodigepalli KM et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  59. In vivo inhibition of miR-155 significantly alters post-stroke inflammatory response
    Authors: Juan Carlos Pena-Philippides, Ernesto Caballero-Garrido, Tamar Lordkipanidze, Tamara Roitbak
    Journal of Neuroinflammation
  60. Active immunization against complement factor C5a: a new therapeutic approach for Alzheimer’s disease
    Authors: Christine Landlinger, Lisa Oberleitner, Petra Gruber, Birgit Noiges, Kristyna Yatsyk, Radmila Santic et al.
    Journal of Neuroinflammation
  61. Molecular profile of cochlear immunity in the resident cells of the organ of Corti
    Authors: Qunfeng Cai, R Robert Vethanayagam, Shuzhi Yang, Jonathan Bard, Jennifer Jamison, Daniel Cartwright et al.
    Journal of Neuroinflammation
  62. Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease
    Authors: Caitlin M. Braitsch, Onur Kanisicak, Jop H. van Berlo, Jeffery D. Molkentin, Katherine E. Yutzey
    Journal of Molecular and Cellular Cardiology
  63. Growth and maturation of heart valves leads to changes in endothelial cell distribution, impaired function, decreased metabolism and reduced cell proliferation
    Authors: Lindsey J. Anstine, Chris Bobba, Samir Ghadiali, Joy Lincoln
    Journal of Molecular and Cellular Cardiology
  64. Regulatory T cell transfer ameliorates lymphedema and promotes lymphatic vessel function
    Authors: Epameinondas Gousopoulos, Steven T. Proulx, Samia B. Bachmann, Jeannette Scholl, Dimitris Dionyssiou, Efterpi Demiri et al.
    JCI Insight
  65. Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth
    Authors: Julia Gschwend, Samantha P.M. Sherman, Frederike Ridder, Xiaogang Feng, Hong-Erh Liang, Richard M. Locksley et al.
    Journal of Experimental Medicine
  66. Contribution of Extra-Cardiac Cells in Murine Heart Valves is Age-Dependent.
    Authors: Anstine LJ, Horne TE, Horwitz EM, Lincoln J.
    J Am Heart Assoc
  67. Local Macrophage-Related Immune Response Is Involved in Cochlear Epithelial Damage in Distinct Gjb2-Related Hereditary Deafness Models
    Authors: Xu K, Chen S, Xie L, et al.
    Frontiers in cell and developmental biology
  68. Endothelial Cell Lineage Analysis Does Not Provide Evidence for EMT in Adult Valve Homeostasis and Disease
    Authors: Andrew J. Kim, Christina M. Alfieri, Katherine E. Yutzey
    The Anatomical Record

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Mouse CD45 Antibody
By Anonymous on 10/05/2023
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Lung tissue Species: Mouse

DAPI (Blue)
CD45 (Yellow)

Immunocytochemistry/Immunofluorescence Mouse CD45 Antibody AF114
Mouse CD45 Antibody
By Anonymous on 11/08/2022
Application: IHC Sample Tested: retinal faltmounts Species: mice
Immunohistochemistry Mouse CD45 Antibody AF114