Mouse ADAM15 Ectodomain Antibody

Name: Mouse ADAM15 Ectodomain Antibody
Brand: R&D Systems
SKU: MAB945
Rating: 4.5 (2 reviews)

Catalog #: MAB945
1 Citation 2 Reviews Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB945
MAB945-SP

All ADAM15 Antibodies

Product Details

Citations (1)

FAQs

Supplemental Products

Reviews (2)

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse ADAM15 Ectodomain Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse ADAM15 Ectodomain in Western blots. In Western blots, no cross-reactivity with recombinant human ADAM8, 9, 15, 17, or recombinant mouse ADAM10 is observed.

Source

Monoclonal Rat IgG_2A Clone # 140104

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse ADAM15
Arg18-Ser694
Accession # O88839

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Mouse ADAM15

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: ADAM15

ADAM15, also known as MDC15 or metargidin, is a widely expressed metalloproteinase. It is a type I membrane protein that may be involved in cell adhesion and shedding of cell surface proteins.

Long Name

A Disintegrin and Metalloprotease-like Domain 15

Entrez Gene IDs

8751 (Human); 11490 (Mouse)

Alternate Names

ADAM 15; ADAM metallopeptidase domain 15; ADAM15; disintegrin-like, and cysteine-rich protein 15; EC 3.4.24; MDC15; MDC-15; Metargidin

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse ADAM15 Ectodomain Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization.
Authors: Xie B, Shen J, Dong A, Swaim M, Hackett SF, Wyder L, Worpenberg S, Barbieri S, Campochiaro PA
FASEB J., 2008-04-01;22(8):2775-83.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot