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MLN 4760

Catalog #: 3345 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3345/2
MLN 4760 | CAS No. 305335-31-3 | ACE Inhibitors
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Description: Potent and selective angiotensin-converting enzyme 2 (ACE2) inhibitor

Chemical Name: N-[(1S)-1-Carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]-L-histidine

Purity: ≥98%

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Biological Activity

MLN 4760 is a highly potent, cell-permeable and selective inhibitor of angiotensin converting enzyme 2 (ACE2) (IC50 = 0.44 nM). MLN 4760 inhibits production of angiotensin (1-7) from angiotensin II and reduces ACE2 expression and activity in an animal model of lung inflammation.

Technical Data

M.Wt:
428.31
Formula:
C19H23Cl2N3O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
305335-31-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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