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MB 0223

Catalog #: 6799 Datasheet / COA / SDS

Discontinued Product

6799 has been discontinued.
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MB 0223 | CAS No. 2247732-89-2 | Dynamin Inhibitors
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Description: Dynamin-related GTPase DRP1 partial inhibitor

Chemical Name: 4-Methyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-N-(4-(pyridin-3-yl)phenyl)-1H-pyrrole-2-carboxamide

Purity: ≥98%

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Biological Activity

MB 0223 is a dynamin-related GTPase DRP1 partial inhibitor (IC50 = 1.2 μM). Selective for DRP1 over other dynamin-related GTPases, OPA1 and DYN1. Increases mitochondrial DNA levels in mfn1- knockout MEFs deficient in mitochondrial fusion.

Technical Data

M.Wt:
457.59
Formula:
C26H27N5OS
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2247732-89-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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