Lys-[Des-Arg9]Bradykinin
![Lys-[Des-Arg9]Bradykinin](https://resources.rndsystems.com/images/datasheets/structures/lys-des-arg9-bradykinin_3225.png "Lys-[Des-Arg9]Bradykinin")
Purity: ≥95%
Biological Activity
Lys-[Des-Arg9]Bradykinin is an endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. 16-fold more potent than [Des-Arg9]-Bradykinin (Cat No. 3005).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Hypotensive effects of Lys-des-Arg9-Bradykinin and metabolically protected agonists of B1 receptors for kinins.
Drapeau et al.
J.Pharmacol.Exp.Ther., 1991;259:997 -
Classification of kinin receptors.
Regoli et al.
Biol.Chem., 2001;382:31 -
International union of pharmacology. LV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences.
Leeb-Lundberg et al.
Pharmacol.Rev., 2005;57:27
Product Datasheets
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Citation for Lys-[Des-Arg9]Bradykinin
The citations listed below are publications that use Tocris products. Selected citations for Lys-[Des-Arg9]Bradykinin include:
1 Citation: Showing 1 - 1
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Modulation of cardiac vagal tone by bradykinin acting on nucleus ambiguus.
Authors: Brailoiu
Neuroscience 2017;365:23
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