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Lamotrigine

Catalog #: 1611
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1611/10
1611/50
Lamotrigine | CAS No. 84057-84-1 | Glutamate Receptor Compounds
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Description: Inhibits glutamate release. Anticonvulsant

Chemical Name: 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine

Purity: ≥99%

Product Details
Citations (2)
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Biological Activity

Lamotrigine is an anticonvulsant. Inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents. Also blocks heterologously expressed and native α4β2 nAChRs with a similar affinity to Na+ channels.

Water-soluble Salt also available.

Technical Data

M.Wt:
256.09
Formula:
C9H7Cl2N5
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
84057-84-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline
Other Product-Specific Information:

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Citations for Lamotrigine

The citations listed below are publications that use Tocris products. Selected citations for Lamotrigine include:

2 Citations: Showing 1 - 2

  1. Different pH-sensitivity patterns of 30 sodium channel inhibitors suggest chemically different pools along the access pathway.
    Authors: Lazar Et al.
    Front Pharmacol  2015;6:210
  2. Characterization of the role of HCN channels in β3-adrenoceptor mediated rat bladder relaxation.
    Authors: Kashyap Et al.
    J Neurosci  2015;2

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