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Lamotrigine isethionate

Catalog #: 2289
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2289/10
2289/50
Lamotrigine isethionate | CAS No. 113170-86-8 | Glutamate Receptor Compounds
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Description: Inhibits glutamate release. Water-soluble salt of lamotrigine (Cat. No. 1611)

Chemical Name: 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine isethionate

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity

Lamotrigine isethionate is a water-soluble salt of lamotrigine (Cat. No. 1611). Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.

Technical Data

M.Wt:
382.22
Formula:
C9H7Cl2N5.C2H6O4S
Solubility:
Soluble to 100 mM in water with gentle warming
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
113170-86-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline

Background References

  1. Lamotrigine reduces voltage-gated sodium currents in rat central neurons in culture.
    Zona and Avoli
    Epilepsia, 1997;38:522
  2. Cardioprotective effect of lamotr. after focal ischemia in rats.
    Smith and Meldrum
    Stroke, 1995;26:117
  3. Modulation of calcium and potassium currents by lamotr.
    Grunze et al.
    Neuropsychobiology, 1998;38:131
  4. Neurochemical and behavioral aspects of lamotr.
    Leach et al.
    Epilepsia, 1991;32:S4

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Citation for Lamotrigine isethionate

The citations listed below are publications that use Tocris products. Selected citations for Lamotrigine isethionate include:

1 Citation: Showing 1 - 1

  1. Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K+ Channel THIK-1.
    Authors: Madry Et al.
    Neuron  2018;97:299

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