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L-Kynurenine

Catalog #: 4393
1 Citation 1 Review Datasheet / COA / SDS

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4393 has been discontinued.
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L-Kynurenine | CAS No. 2922-83-0 | Other Tryptophan 2,3 Dioxygenase Compounds
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Description: Tryptophan catabolite; endogenous aryl hydrocarbon receptor ligand

Chemical Name: L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

Purity: ≥98%

Product Details
Citations (1)
Reviews (1)
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

L-Kynurenine is a tryptophan catabolite; endogenous activator of the aryl hydrocarbon receptor (AhR). Immunosuppressant; suppresses allogeneic T cell proliferation.

Technical Data

M.Wt:
208.21
Formula:
C10H12N2O3
Solubility:
Soluble to 10 mM in water and to 10 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
2922-83-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor.
    Opitz et al.
    Nature, 2011;478:197

Product Datasheets

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Citation for L-Kynurenine

The citations listed below are publications that use Tocris products. Selected citations for L-Kynurenine include:

1 Citation: Showing 1 - 1

  1. Correlation Patterns Among B7 Family Ligands and Tryptophan Degrading Enzymes in Hepatocellular Carcinoma.
    Authors: Bassel F Et al.
    Front Oncol  2020;10:1632

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Happy with purchase
By Anonymous on 08/20/2018

Compound was clean and active in cell based assays. Dissolved in DMSO or HCL.

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