L-DOPA
Chemical Name: L-3,4-Dihydroxyphenylalanine
Purity: ≥98%
Biological Activity
L-DOPA is an immediate precursor of dopamine, produced by tyrosine hydroxylase. Displays antiParkinsonian activity.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Levodopa-induced dyskinesia and striatal signaling pathways.
Pisani and Shen
Proc.Natl.Acad.Sci.USA, 2009;106:2973
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Citations for L-DOPA
The citations listed below are publications that use Tocris products. Selected citations for L-DOPA include:
5 Citations: Showing 1 - 5
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Dopamine signaling modulates microglial NLRP3 inflammasome activation: implications for Parkinson's disease.
Authors: Robert Et al.
J Neuroinflammation 2022;19:50
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Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways.
Authors: Marc Et al.
Cell Rep 2021;35:109136
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Cocaine shifts dopamine D2 receptor sensitivity to gate conditioned behaviors.
Authors: Christopher P Et al.
Neuron 2021;109:3421-3435.e5
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Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum.
Authors: Alexander G Et al.
Elife 2021;10
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A Basal Ganglia Circuit Sufficient to Guide Birdsong Learning.
Authors: Xiao Et al.
Neuron 2018;98:208
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