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KISS1 305

Catalog #: 7490 Datasheet / COA / SDS

Discontinued Product

7490 has been discontinued.
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KISS1 305
1 Image
Description: Kisspeptin1 receptor agonist

Purity: ≥95%

Product Details
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Biological Activity Technical Data Additional Information Product Datasheets Calculators

Biological Activity

KISS1 305 is a potent Kisspeptin1 receptor agonist (EC50 = 10 nM). It binds with high affinity to rat and human KISS1 receptors with Ki values of 0.14 nM and 0.11 nM respectively. In vivo, chronic administration of KISS1 305 reduces plasma testosterone and genital organ weights in male rats.

External Portal Information

Chemicalprobes.org is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of KISS1-305 is reviewed on the chemical probes website.

Technical Data

M.Wt:
1165.32
Formula:
C56H76N16O12
Sequence:
YXNSFGLRF

(Modifications: Tyr-1 = D-Tyr, X-2 = D-Pya(4), Gly-6 = AzaGly, Arg-8 = Arg(Me), Phe-9 = C-terminal amide

Solubility:
Soluble to 1 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
872717-97-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the KISS1-305 probe summary on the SGC website.

Product Datasheets

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