Human SLC22A2/OCT2 Alexa Fluor® 488-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: SLC22A2/OCT2

Solute carrier family 22 member 2 (SLC22A2; also hOCT2) is a 65 kDa member of the major facilitator superfamily and organic cation transporter family of proteins.   Human SLC22A2 is synthesized as a multipass transmembrane protein that is 555 amino acids (aa) in length.  Human SLC22A2 contains one potential site for N-linked glycosylation.  There are also two additional isoforms for human SLC22A2.   Isoform 2 has a 57 aa substitution for aa 427-483 and a deletion of the 72 aa at positions 484-555.   Isoform 3 has an 18 aa substitution for aa 225-242 and a deletion of residues 243-555.  SLC22A2 has its highest expression in the kidney.  It is also expressed at lower levels in neurons of the cerebral cortex and in various subcortical nuclei.

Product Datasheets

Product Specific Notices

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

Related Research Areas

• Neurotransmitter Transporters
• Renal Markers
• Solute Carrier Family (SLC)