Human S1P₄/EDG-6 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB10321T Datasheet / COA / SDS

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FAB10321T-100UG

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Human S1P₄/EDG-6 Alexa Fluor® 594-conjugated Antibody Summary

Specificity

Detects human S1P₄/EDG‑6 transfectants but not the parental cell line in Flow Cytometry.

Source

Monoclonal Mouse IgG_2B Clone # 1012512

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

NS0 mouse myeloma cell line transfected with human S1P₄/EDG‑6
Met1-Ile384
Accession # O95977

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

0.25-1 µg/10⁶ cells

HEK293 Human Cell Line Transfected with Human S1P₄/EDG-6 and eGFP

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: S1P4/EDG-6

EDG-6 belongs to the G protein-coupled receptor 1 family. It is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. EDG-6 is a receptor for the lysosphingolipid sphingosine 1- phosphate (S1P), a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. EDG-6 may be involved in cell migration processes that are specific for lymphocytes.

Long Name

Endothelial Differentiation Gene 5

Entrez Gene IDs

8698 (Human); 13611 (Mouse); 314649 (Rat)

Alternate Names

EDG6; EDG6S1P receptor Edg-6; Endothelial differentiation G-protein coupled receptor 6; endothelial differentiation, G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor6,endothelial differentiation, G protein coupled receptor 6; S1P receptor 4; S1P4; S1P4LPC1; S1PR4; SLP4; sphingosine 1-phosphate receptor 4; Sphingosine 1-phosphate receptor Edg-6; sphingosine-1-phosphate receptor 4

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Product Datasheet

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Product Specific Notices

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.