Human IL-8/CXCL8 Antibody

Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage
Authors: Juan Antonio Fafián-Labora, Jose Antonio Rodríguez-Navarro, Ana O’Loghlen
Cell Metabolism

Biological Characterization of Commercial Recombinantly Expressed Immunomodulating Proteins Contaminated with Bacterial Products in the Year 2020: The SAA3 Case
Authors: S Abouelasra, M De Bondt, N Berghmans, M Gouwy, VLS de Oliveir, SC Oliveira, FA Amaral, P Proost, J Van Damme, S Struyf, M De Buck
Mediators Inflamm., 2020-07-06;2020(0):6087109.

IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib
Authors: Romaine I. Fernando, Duane H. Hamilton, Charli Dominguez, Justin M. David, Kristen K. McCampbell, Claudia Palena
Oncotarget

A patient-designed tissue-engineered model of the infiltrative glioblastoma microenvironment
Authors: R. C. Cornelison, J. X. Yuan, K. M. Tate, A. Petrosky, G. F. Beeghly, M. Bloomfield et al.
npj Precision Oncology

Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response
Authors: Edmée Eyraud, Elise Maurat, Jean-Marc Sac-Epée, Pauline Henrot, Maeva Zysman, Pauline Esteves et al.
eLife

CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells
Authors: Amy Sinclair, Laura Park, Mansi Shah, Mark Drotar, Simon Calaminus, Lisa E. M. Hopcroft et al.
Blood

Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation
Authors: Britt-Marie Sundblad, Britt-Marie Sundblad, Bettina Levänen, Bettina Midander, Anneli Midander, Anneli Julander et al.
International Journal of Chronic Obstructive Pulmonary Disease

SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells
Authors: Hoai-Nga Thi Nguyen, Marie Kawahara, Cat-Khanh Vuong, Mizuho Fukushige, Toshiharu Yamashita, Osamu Ohneda
Frontiers in Oncology

Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers
Authors: Pamela J. Maxwell, Melanie McKechnie, Christopher W. Armstrong, Judith M. Manley, Chee Wee Ong, Jenny Worthington et al.
Molecular Cancer Research

Cystathionine-beta -synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation
Authors: Haoran Zhu, Keefe T Chan, Xinran Huang, Carmelo Cerra, Shaun Blake, Anna S Trigos et al.
eLife

ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL‑8/Notch signaling cascade
Authors: Valerio Ciccone, Erika Terzuoli, Emma Ristori, Arianna Filippelli, Marina Ziche, Lucia Morbidelli et al.
International Journal of Molecular Medicine

Synergism between Hedgehog-GLI and EGFR Signaling in Hedgehog-Responsive Human Medulloblastoma Cells Induces Downregulation of Canonical Hedgehog-Target Genes and Stabilized Expression of GLI1
Authors: Frank Götschel, Daniela Berg, Wolfgang Gruber, Christian Bender, Markus Eberl, Myriam Friedel et al.
PLoS ONE

The Dominant Role of IL-8 as an Angiogenic Driver in a Three-Dimensional Physiological Tumor Construct for Drug Testing
Authors: Pamela H.S. Tan, Su Shin Chia, Siew Lok Toh, James C.H. Goh, Saminathan Suresh Nathan
Tissue Engineering Part A

High tumor levels of IL6 and IL8 abrogate preclinical efficacy of the gamma -secretase inhibitor, RO4929097
Authors: Wei He, Leopoldo Luistro, Daisy Carvajal, Melissa Smith, Tom Nevins, Xuefeng Yin et al.
Molecular Oncology

Serum Amyloid A1 (SAA1) Revisited: Restricted Leukocyte-Activating Properties of Homogeneous SAA1
Authors: Sara Abouelasrar Salama, Mirre De Bondt, Mieke De Buck, Nele Berghmans, Paul Proost, Vivian Louise Soares Oliveira et al.
Frontiers in Immunology

CAR T-Cells Targeting the Integrin alpha v beta 6 and Co-Expressing the Chemokine Receptor CXCR2 Demonstrate Enhanced Homing and Efficacy against Several Solid Malignancies
Authors: Lynsey M. Whilding, Leena Halim, Benjamin Draper, Ana C. Parente-Pereira, Tomasz Zabinski, David Marc Davies et al.
Cancers (Basel)

A novel microRNA-182/Interleukin-8 regulatory axis controls osteolytic bone metastasis of lung cancer
Authors: Ming-Na Zhao, Ling-Fei Zhang, Zhen Sun, Li-Hua Qiao, Tao Yang, Yi-Zhe Ren et al.
Cell Death & Disease

Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance
Authors: Kelvin Yin, Daniel Patten, Sarah Gough, Susana de Barros Gonçalves, Adelyne Chan, Ioana Olan et al.
Genes & Development

Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts
Authors: A Krishnamur, AJ Ytterberg, M Sun, K Sakuraba, J Steen, V Joshua, NK Tarasova, V Malmström, H Wähämaa, B Réthi, AI Catrina
J. Immunol., 2019-04-24;0(0):.

ERK3/MAPK6 controls IL-8 production and chemotaxis
Authors: Katarzyna Bogucka, Malvika Pompaiah, Federico Marini, Harald Binder, Gregory Harms, Manuel Kaulich et al.
eLife

MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8
Authors: Dipa Bhaumik, Gary K. Scott, Shiruyeh Schokrpur, Christopher K. Patil, Arturo V. Orjalo, Francis Rodier et al.
ImpactJ

Chemokine receptor engineering of T cells with CXCR2 improves homing towards subcutaneous human melanomas in xenograft mouse model
Authors: Manja Idorn, Signe Koggersbøl Skadborg, Lauge Kellermann, Hólmfrídur Rósa Halldórsdóttir, Gitte Holmen Olofsson, Özcan Met et al.
OncoImmunology

Induction of Chemokines by Hepatitis C Virus Proteins: Synergy of the Core Protein with Interleukin-1 beta and Interferon-gamma in Liver Bystander Cells
Authors: Sara Abouelasrar Salama, Mieke Gouwy, Alexandra De Zutter, Noëmie Pörtner, Lotte Vanbrabant, Nele Berghmans et al.
Journal of Interferon & Cytokine Research

The Cytoprotective Effects of Human Endothelial Progenitor Cell-Conditioned Medium against an Ischemic Insult Are Not Dependent on VEGF and IL-8
Authors: Stefano Di Santo, Anna-Lena Fuchs, Ramesh Periasamy, Stefanie Seiler, Hans Rudolf Widmer
Cell Transplantation

Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
Authors: Akilan Krishnamurthy, Vijay Joshua, Aase Haj Hensvold, Tao Jin, Meng Sun, Nancy Vivar et al.
Annals of the Rheumatic Diseases

Application of the Mirrorball High-Sensitivity Cytometer to Multiplexed Assays for Antibody Drug Discovery
Authors: Elizabeth England, Philip Newton, Frances Neal, Lisa Kitching, Caroline Colley, Christine J. Rossant
J Biomol Screen

Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival
Authors: M Dietachmay, A Rathakrish, O Karpiuk, F von Zweydo, T Engleitner, V Fernández-, P Schenk, M Ueffing, R Rad, M Eilers, CJ Gloeckner, K Clemm von, F Bassermann
Nat Commun, 2020-03-09;11(1):1268.

Bone marrow-derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition.
Authors: Pietrovito L, Leo A, Gori V et al.
Mol Oncol.

Acceleration of clear cell renal cell carcinoma growth in mice following bevacizumab/Avastin treatment: the role of CXCL cytokines
Authors: R Grepin, M Guyot, M Jacquin, J Durivault, E Chamorey, A Sudaka et al.
Oncogene

Protein kinase D1-mediated classical protein secretory pathway regulates oncogene Ras-induced senescent response
Authors: Y Su, P Wang, H Shen, Z Sun, C Xu, G Li, T Tong, J Chen
J. Cell. Sci., 2018-03-16;0(0):.

Interleukin‑8 released by cancer‑associated fibroblasts attenuates the autophagy and promotes the migration of ovarian cancer cells
Authors: Suyanee Thongchot, Pranisa Jamjuntra, Suwanit Therasakvichya, Malee Warnnissorn, Alessandra Ferraresi, Peti Thuwajit et al.
International Journal of Oncology

Characterization of Innate Immunity in an Extended Whole Blood Model of Human Islet Allotransplantation
Authors: Maria Hårdstedt, Susanne Lindblom, Alex Karlsson-Parra, Bo Nilsson, Olle Korsgren
Cell Transplantation

Titration of RAS alters senescent state and influences tumour initiation
Authors: Chan, ASL;Zhu, H;Narita, M;Cassidy, LD;Young, ARJ;Bermejo-Rodriguez, C;Janowska, AT;Chen, HC;Gough, S;Oshimori, N;Zender, L;Aitken, SJ;Hoare, M;Narita, M;
Nature
Species: Mouse
Sample Types: Cell Lysates, Whole Tissue
Applications: Immunohistochemistry, Western Blot

Paracrinal regulation of neutrophil functions by coronaviral infection in iPSC-derived alveolar type II epithelial cells
Authors: Chien, Y;Huang, XY;Yarmishyn, AA;Chien, CS;Liu, YH;Hsiao, YJ;Lin, YY;Lai, WY;Huang, SC;Lee, MS;Chiou, SH;Yang, YP;Chiou, GY;
Virus research
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Catecholamines Promote Ovarian Cancer Progression through Secretion of CXC-Chemokines
Authors: Kim, HJ;Chang, HK;Lee, YM;Heo, K;
International journal of molecular sciences
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Novel Function of Cancer Stem Cell Marker ALDH1A3 in Glioblastoma: Pro-Angiogenesis through Paracrine PAI-1 and IL-8
Authors: Chen Z, Will R, Kim SN et al.
Cancers (Basel)

Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation
Authors: Shen, CJ;Chan, RH;Lin, BW;Li, NC;Huang, YH;Chang, WC;Chen, BK;
Theranostics
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

Suppression of TGF beta -Induced Interleukin-6 Secretion by Sinulariolide from Soft Corals through Attenuation of the p38-NF-kB Pathway in Carcinoma Cells
Authors: Yang, JL;Lin, WL;Tai, SB;Ciou, YS;Chung, CL;Chen, JJ;Liu, PF;Lin, MW;Chen, CL;
International journal of molecular sciences
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer
Authors: Fu, X;Pereira, R;Liu, CC;De Angelis, C;Shea, MJ;Nanda, S;Qin, L;Mitchell, T;Cataldo, ML;Veeraraghavan, J;Sethunath, V;Giuliano, M;Gutierrez, C;Győrffy, B;Trivedi, MV;Cohen, O;Wagle, N;Nardone, A;Jeselsohn, R;Rimawi, MF;Osborne, CK;Schiff, R;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

IL8 derived from macrophages inhibits CD8+ T-cell function by downregulating TIM3 expression through IL8-CXCR2 axis in patients with advanced colorectal cancer
Authors: Zhao, C;Wang, D;Li, Z;Zhang, Z;Xu, Y;Liu, J;Lei, Q;Han, D;Huo, Y;Liu, S;Li, L;Zhang, Y;
International immunopharmacology
Species: Human
Sample Types: Whole Cells, Whole Tissue
Applications: ICC, IHC, Neutralization

Discovery of senolytics using machine learning
Authors: Smer-Barreto, V;Quintanilla, A;Elliott, RJR;Dawson, JC;Sun, J;Campa, VM;Lorente-Macías, Á;Unciti-Broceta, A;Carragher, NO;Acosta, JC;Oyarzún, DA;
Nature communications
Species: Human
Sample Types: Whole Cells
Applications: ICC

Gastric cancer cell-originated small extracellular vesicle induces metabolic reprogramming of BM-MSCs through ERK-PPAR?-CPT1A signaling to potentiate lymphatic metastasis
Authors: Huang, J;Wang, X;Wen, J;Zhao, X;Wu, C;Wang, L;Cao, X;Dong, H;Xu, X;Huang, F;Zhu, W;Wang, M;
Cancer cell international
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

RanBP1: A Potential Therapeutic Target for Cancer Stem Cells in Lung Cancer and Glioma
Authors: YJ Kahm, IG Kim, RK Kim
International Journal of Molecular Sciences, 2023-04-06;24(7):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Effect of teriparatide on drug treatment of tuberculous spondylitis: an experimental study
Authors: S Lee, YJ Seo, JY Choi, X Che, HJ Kim, SY Eum, MS Hong, SK Lee, DC Cho
Scientific Reports, 2022-12-15;12(1):21667.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Capture

CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-inducing phenotype
Authors: W Zeng, L Xiong, W Wu, S Li, J Liu, L Yang, L Lao, P Huang, M Zhang, H Chen, N Miao, Z Lin, Z Liu, X Yang, J Wang, P Wang, E Song, Y Yao, Y Nie, J Chen, D Huang
Oncogene, 2022-11-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

Modeling human HSV infection via a vascularized immune-competent skin-on-chip platform
Authors: S Sun, L Jin, Y Zheng, J Zhu
Nature Communications, 2022-09-19;13(1):5481.
Species: Human
Sample Types: Whole Tissue
Applications: Neutralization

The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells
Authors: MF Santolla, M Talia, F Cirillo, D Scordamagl, S De Rosis, A Spinelli, AM Miglietta, B Nardo, G Filippelli, EM De Frances, A Belfiore, R Lappano, M Maggiolini
Cells, 2022-08-04;11(15):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance
Authors: R Islam, J Mishra, NS Polavaram, S Bhattachar, Z Hong, S Bodas, S Sharma, A Bouska, T Gilbreath, AM Said, LM Smith, BA Teply, MH Muders, SK Batra, K Datta, S Dutta
Oncogene, 2022-07-19;40(3):111097.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8
Authors: T Walle, JA Kraske, B Liao, B Lenoir, C Timke, E von Bohlen, F Tran, P Griebel, D Albrecht, A Ahmed, M Suarez-Car, A Jiménez-Sá, T Beikert, A Tietz-Dahl, AN Menevse, G Schmidt, M Brom, JHW Pahl, W Antonopoul, M Miller, RL Perez, F Bestvater, NA Giese, P Beckhove, P Rosenstiel, D Jäger, O Strobel, D Pe'er, N Halama, J Debus, A Cerwenka, PE Huber
Science Advances, 2022-03-23;8(12):eabh4050.
Species: Human
Sample Types: Whole Cells
Applications: ICC

Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence
Authors: E Lieschke, Z Wang, C Chang, CE Weeden, GL Kelly, A Strasser
Cell Death and Differentiation, 2022-03-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC

Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4
Authors: F Yang, XQ Liu, JZ He, SP Xian, PF Yang, ZY Mai, M Li, Y Liu, XD Zhang
Journal of Cellular and Molecular Medicine, 2022-02-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy
Authors: RM Urbantat, C Jelgersma, S Brandenbur, M Nieminen-K, I Kremenetsk, J Zollfrank, S Mueller, K Rubarth, A Koch, P Vajkoczy, G Acker
International Journal of Molecular Sciences, 2021-10-16;22(20):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC

Extracellular Hsp90alpha Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer
Authors: Q Hou, S Chen, Q An, B Li, Y Fu, Y Luo
International Journal of Molecular Sciences, 2021-07-20;22(14):.
Species: Human
Sample Types: Cell Lysates, Whole Cells, Whole Tissue
Applications: Co-Immunoprecipitation, ICC, IHC, Western Blot

COX2 regulates senescence secretome composition and senescence surveillance through PGE2
Authors: S Gonçalves, K Yin, Y Ito, A Chan, I Olan, S Gough, L Cassidy, E Serrao, S Smith, A Young, M Narita, M Hoare
Cell Reports, 2021-03-16;34(11):108860.
Species: Human
Sample Types: Cell Lysates, Whole Cells
Applications: ICC, Western Blot

Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair
Authors: H Israelov, O Ravid, D Atrakchi, D Rand, S Elhaik, Y Bresler, R Twitto-Gre, L Omesi, S Liraz-Zalt, F Gosselet, M Schnaider, I Cooper
J Neuroinflammation, 2020-09-09;17(1):267.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Chemotherapy-induced IL-8 upregulates MDR1/ABCB1 in tumor blood vessels and results in unfavorable outcome
Authors: H Kikuchi, N Maishi, DA Annan, M Towfik Ala, R Ibrahim Ha, M Sato, M Morimoto, R Takeda, K Ishizuka, R Matsumoto, T Akino, K Tsuchiya, T Abe, T Osawa, N Miyajima, S Maruyama, T Harabayash, M Azuma, K Yamashiro, K Ameda, A Kashiwagi, Y Matsuno, Y Hida, N Shinohara, K Hida
Cancer Res., 2020-06-14;0(0):.
Species: Human
Sample Types: Whole Cells, Whole Tissue
Applications: IHC, Neutralization

Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
Authors: Q Ji, L Zhou, H Sui, L Yang, X Wu, Q Song, R Jia, R Li, J Sun, Z Wang, N Liu, Y Feng, X Sun, G Cai, Y Feng, J Cai, Y Cao, G Cai, Y Wang, Q Li
Nat Commun, 2020-03-05;11(1):1211.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Microenvironmental IL1beta promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
Authors: R Eyre, DG Alférez, A Santiago-G, K Spence, JC McConnell, C Hart, BM Simões, D Lefley, C Tulotta, J Storer, A Gurney, N Clarke, M Brown, SJ Howell, AH Sims, G Farnie, PD Ottewell, RB Clarke
Nat Commun, 2019-11-01;10(1):5016.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Neutrophil Activities in Human Ocular Toxoplasmosis: An In Vitro Study With Human Cells
Authors: LM Ashander, S Lie, Y Ma, E Rochet, JM Washington, JM Furtado, B Appukuttan, JR Smith
Invest. Ophthalmol. Vis. Sci., 2019-11-01;60(14):4652-4660.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization
Authors: A Schulz, L Jiang, L de Vor, M Ehrström, F Wermeling, L Eidsmo, K Melican
Cell Rep, 2019-10-29;29(5):1074-1081.e5.
Species: Human
Sample Types: Tissue Homogenates
Applications: Blocking

TCR- or Cytokine-Activated CD8+ Mucosal-Associated Invariant T Cells Are Rapid Polyfunctional Effectors That Can Coordinate Immune Responses
Authors: R Lamichhane, M Schneider, SM de la Harp, TWR Harrop, RF Hannaway, PK Dearden, JR Kirman, JDA Tyndall, AJ Vernall, JE Ussher
Cell Rep, 2019-09-17;28(12):3061-3076.e5.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Bioassay

Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3
Authors: M Borghesan, J Fafián-Lab, O Eleftheria, P Carpintero, M Paez-Ribes, G Vizcay-Bar, A Swisa, D Kolodkin-G, P Ximénez-Em, R Lowe, B Martín-Mar, H Peinado, J Muñoz, RA Fleck, Y Dor, I Ben-Porath, A Vossenkamp, D Muñoz-Espi, A O'Loghlen
Cell Rep, 2019-06-25;27(13):3956-3971.e6.
Species: Human
Sample Types: Cell Lysates, Extracellular Vesicles
Applications: ICC, Western Blot

Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging
Authors: DP Muñoz, SM Yannone, A Daemen, Y Sun, F Vakar-Lope, M Kawahara, AM Freund, F Rodier, JD Wu, PY Desprez, DH Raulet, PS Nelson, LJ van 't Vee, J Campisi, JP Coppé
JCI Insight, 2019-06-11;5(0):.
Species: Human
Sample Types: Whole Cells
Applications: IHC

The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection
Authors: L Miarka, C Hauser, O Helm, D Holdhof, S Beckinger, JH Egberts, JP Gundlach, L Lenk, S Rahn, W Mikulits, A Trauzold, S Sebens
Cancers (Basel), 2019-05-29;11(6):.
Species: Human
Sample Types: Transfected Whole Cells
Applications: Neutralization

Differentiated fibrocytes assume a functional mesenchymal phenotype with regenerative potential
Authors: C Ling, K Nishimoto, Z Rolfs, LM Smith, BL Frey, NV Welham
Sci Adv, 2019-05-08;5(5):eaav7384.
Species: Rat
Sample Types: In Vivo
Applications: Bioassay

Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity
Authors: EP Reeves, DM Dunlea, K McQuillan, CA O'Dwyer, TP Carroll, R Saldova, PR Akepati, MR Wormald, OJ McElvaney, V Shutchaida, M Henry, P Meleady, J Keenan, DC Liberti, DN Kotton, PM Rudd, AA Wilson, NG McElvaney
J. Immunol., 2019-02-22;0(0):.
Species: Human
Sample Types: Protein
Applications: Binding Assay

Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth
Authors: J Zhang, H Li, Q Wu, Y Chen, Y Deng, Z Yang, L Zhang, B Liu
Redox Biol, 2019-02-06;22(0):101116.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Neutralization

Varicella Zoster Virus Induces Differential Cell-Type Specific Responses in Human Corneal Epithelial Cells and Keratocytes
Authors: CN Como, AN Bubak, AM Blackmon, D Jones, NH Mueller, R Davidson, MA Nagel
Invest. Ophthalmol. Vis. Sci., 2019-02-01;60(2):704-711.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

L-selectin expression is regulated by CXCL8-induced reactive oxygen species produced during human neutrophil rolling
Authors: MJ Domínguez-, E Armas-Gonz, A Herrera-Ga, M Arce-Franc, M Feria, M Vicente-Ma, A Martínez-R, F Sánchez-Ma, F Díaz-Gonzá
Eur. J. Immunol., 2018-12-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
Authors: SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, E Chevet, RM Dwyer, A Oommen, P Legembre, F Godey, EC Madden, B Leuzzi, J Obacz, Q Zeng, JB Patterson, R Jäger, AM Gorman, A Samali
Nat Commun, 2018-08-15;9(1):3267.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases
Authors: B Gril, AN Paranjape, S Woditschka, E Hua, EL Dolan, J Hanson, X Wu, W Kloc, E Izycka-Swi, R Duchnowska, R P?ksa, W Biernat, J Jassem, N Nayyar, PK Brastianos, OM Hall, CJ Peer, WD Figg, GT Pauly, C Robinson, S Difilippan, E Bialecki, P Metellus, JP Schneider, PS Steeg
Psychoneuroendocrinology, 2018-07-13;9(1):2705.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

ShRNA-mediated knock-down of CXCL8 inhibits tumor growth in colorectal liver metastasis
Authors: A Kumar, M Cherukumil, SH Mahmoudpou, K Brand, OR Bandapalli
Biochem. Biophys. Res. Commun., 2018-04-23;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis
Authors: Q Liu, A Li, S Yu, S Qin, N Han, RG Pestell, X Han, K Wu
J Hematol Oncol, 2018-04-10;11(1):53.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Age-Related Changes to Human Tear Composition
Authors: A Micera, A Di Zazzo, G Esposito, R Longo, W Foulsham, R Sacco, R Sgrulletta, S Bonini
Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):2024-2031.
Species: Human
Sample Types: Tears
Applications: Western Blot

Intestinal mucin activates human dendritic cells and IL-8 production in a glycan-specific manner
Authors: F Melo-Gonza, TM Fenton, C Forss, C Smedley, A Goenka, AS MacDonald, DJ Thornton, MA Travis
J. Biol. Chem., 2018-03-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Galectin-3 is an amplifier of the interleukin-1?-mediated inflammatory response in corneal keratinocytes
Authors: Y Uchino, AM Woodward, J Mauris, K Peterson, P Verma, UJ Nilsson, J Rajaiya, P Argüeso
Immunology, 2018-02-15;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Western Blot

HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome
Authors: S di Martino, CA Amoreo, B Nuvoli, R Galati, S Strano, F Facciolo, G Alessandri, HI Pass, G Ciliberto, G Blandino, R De Maria, M Cioce
Oncogene, 2018-01-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Inhibition

Endothelial cell leptin receptors, leptin and interleukin-8 in the pathogenesis of preeclampsia: An in-vitro study
Authors: S Arl?er
Turk J Obstet Gynecol, 2017-12-30;14(4):220-227.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease
Authors: J Ikari, AJ Nelson, J Obaid, A Giron-Mart, K Ikari, F Makino, S Iwasawa, Y Gunji, M Farid, X Wang, H Basma, D Demeo, C Feghali-Bo, O Holz, K Rabe, X Liu, SI Rennard
PLoS ONE, 2017-09-07;12(9):e0184039.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development (Capture)

Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease
Authors: MM White, P Geraghty, E Hayes, S Cox, W Leitch, B Alfawaz, GM Lavelle, OJ McElvaney, R Flannery, J Keenan, P Meleady, M Henry, M Clynes, C Gunaratnam, NG McElvaney, EP Reeves
EBioMedicine, 2017-08-16;23(0):173-184.
Species: Human
Sample Types: Plasma
Applications: ELISA Development (Capture)

Human adipose-derived mesenchymal stem cell-secreted CXCL1 and CXCL8 facilitate breast tumor growth by promoting angiogenesis
Authors: Y Wang, J Liu, Q Jiang, J Deng, F Xu, X Chen, F Cheng, Y Zhang, Y Yao, Z Xia, X Xu, X Su, M Huang, L Dai, Y Yang, S Zhang, D Yu, RC Zhao, Y Wei, H Deng
Stem Cells, 2017-06-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells
Authors: B Tian, A Al-Moujahe, P Bouzika, Y Hu, S Notomi, P Tsoka, JW Miller, H Lin, DG Vavvas
Sci Rep, 2017-05-24;7(1):2329.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

Disruption of outer blood-retinal barrier by Toxoplasma gondii-infected monocytes is mediated by paracrinely activated FAK signaling
Authors: HB Song, HO Jun, JH Kim, YH Lee, MH Choi, JH Kim
PLoS ONE, 2017-04-13;12(4):e0175159.
Species: Human
Sample Types: Whole Tissue
Applications: Neutralization

Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells
Authors: J Liu, G Song, X Lin, X Pang, T Meng
Exp Ther Med, 2017-02-21;13(4):1447-1455.
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay

Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory FADDosome Complex upon TRAIL Stimulation
Authors: CM Henry, SJ Martin
Mol. Cell, 2017-02-16;65(4):715-729.e5.
Species: Human
Sample Types: Whole Cells
Applications: ICC

Histone Deacetylase (HDAC) Inhibition Induces I?B Kinase (IKK)-dependent Interleukin-8/CXCL8 Expression in Ovarian Cancer Cells
Authors: HR Gatla, Y Zou, MM Uddin, B Singha, P Bu, A Vancura, I Vancurova
J. Biol. Chem., 2017-02-06;292(12):5043-5054.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Novel augmentation by bufalin of protein kinase C-induced cyclooxygenase-2 and IL-8 production in human breast cancer cells
Authors: Yuh-Lin Wu
Innate Immun, 2016-11-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human pancreatic cancer cells induce a MyD88-dependent stromal response to promote a tumor-tolerant immune microenvironment
Cancer Res., 2016-11-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells
Int J Mol Sci, 2016-08-19;17(8):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

NOTCH1 mediates a switch between two distinct secretomes during senescence
Authors: M Hoare, Y Ito, TW Kang, MP Weekes, NJ Matheson, DA Patten, S Shetty, AJ Parry, S Menon, R Salama, R Antrobus, K Tomimatsu, W Howat, PJ Lehner, L Zender, M Narita
Nat. Cell Biol, 2016-08-15;18(9):979-92.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells
Sci Rep, 2016-08-10;6(0):31087.
Species: Bacteria - E. Coli
Sample Types: Cell Lysates
Applications: Immunoprecipitation

The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer
Authors: Z Jing, H Xu, X Chen, Q Zhong, J Huang, Y Zhang, W Guo, Z Yang, S Ding, P Chen, Z Huang
PLoS ONE, 2016-04-14;11(4):e0152789.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Chemokine CCL15 Mediates Migration of Human Bone Marrow-Derived Mesenchymal Stem Cells Toward Hepatocellular Carcinoma.
Authors: Gao Y, Zhou Z, Lu S, Huang X, Zhang C, Jiang R, Yao A, Sun B, Wang X
Stem Cells, 2016-01-13;34(4):1112-22.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop.
Authors: Chen L, Min L, Wang X, Zhao J, Chen H, Qin J, Chen W, Shen Z, Tang Z, Gan Q, Ruan Y, Sun Y, Qin X, Gu J
Cancer Res, 2015-07-21;75(18):3832-41.
Species: Human, Mouse
Sample Types: In Vivo, Whole Cells
Applications: Neutralization

Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer.
Authors: Takeuchi S, Baghdadi M, Tsuchikawa T, Wada H, Nakamura T, Abe H, Nakanishi S, Usui Y, Higuchi K, Takahashi M, Inoko K, Sato S, Takano H, Shichinohe T, Seino K, Hirano S
Cancer Res, 2015-05-07;75(13):2629-40.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Neutralization

Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokines.
Authors: Gouwy M, De Buck M, Portner N, Opdenakker G, Proost P, Struyf S, Van Damme J
Eur J Immunol, 2014-12-01;45(1):101-12.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Urocortin 2 role in placental and myometrial inflammatory mechanisms at parturition.
Authors: Voltolini C, Battersby S, Novembri R, Torricelli M, Severi F, Petraglia F, Norman J
Endocrinology, 2014-11-26;156(2):670-9.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development (Capture)

The effect of the decoy molecule PA401 on CXCL8 levels in bronchoalveolar lavage fluid of patients with cystic fibrosis.
Authors: McElvaney O, O'Reilly N, White M, Lacey N, Pohl K, Gerlza T, Bergin D, Kerr H, McCarthy C, O'Brien M, Adage T, Kungl A, Reeves E, McElvaney N
Mol Immunol, 2014-11-02;63(2):550-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk.
Authors: Kuravi S, McGettrick H, Satchell S, Saleem M, Harper L, Williams J, Rainger G, Savage C
J Immunol, 2014-05-28;193(1):234-43.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Citrullination and proteolytic processing of chemokines by Porphyromonas gingivalis.
Authors: Moelants, Eva A V, Loozen, Gitte, Mortier, Anneleen, Martens, Erik, Opdenakker, Ghislain, Mizgalska, Danuta, Szmigielski, Borys, Potempa, Jan, Van Damme, Jo, Teughels, Wim, Proost, Paul
Infect Immun, 2014-03-31;82(6):2511-9.
Species: Bacteria - Porphyromonas gingivalis
Sample Types: Cell Culture Supernates
Applications: ELISA Development (Detection)

Chemokine CXCL8 promotes HIV-1 replication in human monocyte-derived macrophages and primary microglia via nuclear factor-kappaB pathway.
Authors: Mamik M, Ghorpade A
PLoS ONE, 2014-03-24;9(3):e92145.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Bioassay

Interleukin-1-induced activation of the small GTPase Rac1 depends on receptor internalization and regulates gene expression.
Authors: Windheim M, Hansen B
Cell Signal, 2013-09-28;26(1):49-55.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

CD82/KAI expression prevents IL-8-mediated endothelial gap formation in late-stage melanomas.
Authors: Khanna, P, Chung, C-Y, Neves, R I, Robertson, G P, Dong, C
Oncogene, 2013-07-22;33(22):2898-908.
Species: Human
Sample Types: Cell Culture Supernates, Cell Lysates
Applications: ELISA Development (Capture), Western Blot

Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam.
Authors: Nakajima N, Van Tin N, Sato Y, Thach H, Katano H, Diep P, Kumasaka T, Thuy N, Hasegawa H, San L, Kawachi S, Liem N, Suzuki K, Sata T
Mod Pathol, 2012-11-23;26(3):357-69.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P

Macrophages induce differentiation of plasma cells through CXCL10/IP-10.
J. Exp. Med., 2012-09-17;209(10):1813-23.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Authors: Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, Orthey E, Arumugam T, Leypoldt F, Simova O, Thom V, Friese M, Prinz I, Holscher C, Glatzel M, Korn T, Gerloff C, Tolosa E, Magnus T
Blood, 2012-09-13;120(18):3793-802.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P

Monocytes Induce STAT3 Activation in Human Mesenchymal Stem Cells to Promote Osteoblast Formation.
Authors: Nicolaidou V, Wong MM, Redpath AN
PLoS ONE, 2012-07-03;7(7):e39871.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages.
Authors: Meda C, Molla F, De Pizzol M
J. Immunol., 2012-03-21;188(8):4081-92.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Daily exposure to dust alters innate immunity.
Authors: Sahlander K, Larsson K, Palmberg L
PLoS ONE, 2012-02-15;7(2):e31646.
Species: Human
Sample Types: Serum
Applications: ELISA Development

Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients.
Authors: Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S
Mucosal Immunol, 2011-12-21;5(2):140-9.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Protection from RNA and DNA viruses by IL-32.
Authors: Zepp JA, Nold-Petry CA, Dinarello CA, Nold MF
J. Immunol., 2011-02-23;186(7):4110-8.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Electrochemiluminescent Assay

TH17 cytokines induce human airway smooth muscle cell migration.
Authors: Chang Y, Al-Alwan L, Risse PA, Roussel L, Rousseau S, Halayko AJ, Martin JG, Hamid Q, Eidelman DH
J. Allergy Clin. Immunol., 2011-02-22;127(4):1046-53.e1-2.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Suppression of TNF-alpha and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27.
Authors: Kalliolias GD, Gordon RA, Ivashkiv LB
J. Immunol., 2010-10-22;185(11):7047-56.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Quantitative Validation and Comparison of Multiplex Cytokine Kits
Authors: Joanna L. Richens, Richard A. Urbanowicz, Rebecca Metcalf, Jonathan Corne, Paul O’Shea, Lucy Fairclough
J Biomol Screen

Quantitative Validation and Comparison of Multiplex Cytokine Kits
Authors: Joanna L. Richens, Richard A. Urbanowicz, Rebecca Metcalf, Jonathan Corne, Paul O’Shea, Lucy Fairclough
J Biomol Screen

Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis.
Authors: Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F
J. Immunol., 2010-03-24;184(0):5263-70.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis.
Authors: Reeves EP, Williamson M, Byrne B, Bergin DA, Smith SG, Greally P, O'Kennedy R, O'Neill SJ, McElvaney NG
J. Immunol., 2009-12-21;184(3):1642-52.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
Authors: Rodier F, Coppe JP, Patil CK, Hoeijmakers WA, Munoz DP, Raza SR, Freund A, Campeau E, Davalos AR, Campisi J
Nat. Cell Biol., 2009-07-13;11(8):973-9.
Species: Human
Sample Types: Whole Cells
Applications: ICC

Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.
Authors: Hu H, Kwun J, Aizenstein BD, Knechtle SJ
Transplantation, 2009-06-27;87(12):1814-20.
Species: Human
Sample Types: Urine
Applications: Antibody Array Development

Oxidized alpha1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema.
Authors: Li Z, Alam S, Wang J, Sandstrom CS, Janciauskiene S, Mahadeva R
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-06-12;297(2):L388-400.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma.
Authors: Osei-Kumah A, Smith R, Clifton VL
Cytokine, 2008-07-17;43(2):187-93.
Species: Human
Sample Types: Plasma
Applications: ELISA Development

IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis.
Authors: Skov L, Beurskens FJ, Zachariae CO, Reitamo S, Teeling J, Satijn D, Knudsen KM, Boot EP, Hudson D, Baadsgaard O, Parren PW, van de Winkel JG
J. Immunol., 2008-07-01;181(1):669-79.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Endogenous IL-32 controls cytokine and HIV-1 production.
Authors: Nold MF, Nold-Petry CA, Pott GB, Zepp JA, Saavedra MT, Kim SH, Dinarello CA
J. Immunol., 2008-07-01;181(1):557-65.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Electrochemiluminescent Assay

Expression of CXCL8, CXCR1, and CXCR2 in neurons and glial cells of the human and rabbit retina.
Authors: Goczalik I, Ulbricht E, Hollborn M, Raap M, Uhlmann S, Weick M, Pannicke T, Wiedemann P, Bringmann A, Reichenbach A, Francke M
Invest. Ophthalmol. Vis. Sci., 2008-06-14;49(10):4578-89.
Species: Human, Rabbit
Sample Types: Whole Tissue
Applications: IHC-Fr

Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
J. Clin. Invest., 2007-12-01;117(12):3664-3672.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines.
Authors: Qui H, Ferrell EP, Nolan N, Phelps BH, Tabibiazar R, Whitney DH, Naelfski EA
Clin. Chem., 2007-11-01;53(11):2010-2.
Species: Human
Sample Types: Plasma
Applications: ELISA Development

Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays.
Authors: Pfleger C, Schloot N, ter Veld F
J. Immunol. Methods, 2007-10-22;329(1):214-8.
Species: Human
Sample Types: Serum
Applications: Luminex Development

Eotaxin-2 and colorectal cancer: a potential target for immune therapy.
Authors: Cheadle EJ, Riyad K, Subar D, Rothwell DG, Ashton G, Batha H, Sherlock DJ, Hawkins RE, Gilham DE
Clin. Cancer Res., 2007-10-01;13(19):5719-28.
Species: Human
Sample Types: Tissue Homogenates
Applications: ELISA Development

Ultrasensitive flow-based immunoassays using single-molecule counting.
Authors: Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P
Clin. Chem., 2007-09-21;53(11):1990-5.
Species: Human
Sample Types: Plasma
Applications: ELISA Development

Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells.
Authors: Fitzgerald DC, Meade KG, McEvoy AN, Lillis L, Murphy EP, Machugh DE, Baird AW
Vet. Immunol. Immunopathol., 2007-01-09;116(1):59-68.
Species: Bovine
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts.
Authors: Hatfield K, Ryningen A, Corbascio M, Bruserud O
Int. J. Cancer, 2006-11-15;119(10):2313-21.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion.
Authors: Abe Y, Fornage M, Yang CY, Bui-Thanh NA, Wise V, Chen HH, Rangaraj G, Ballantyne CM
Atherosclerosis, 2006-10-04;192(1):56-66.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors.
Authors: Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sjostedt A, Edebro H, Forsman M, Bystrom M, Pelletier M, Wilson CB, Miller SI, Skerrett SJ, Ernst RK
Infect. Immun., 2006-09-18;74(12):6730-8.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice.
Authors: Rofstad EK, Mathiesen B, Kindem K, Galappathi K
Cancer Res., 2006-07-01;66(13):6699-707.
Species: Complex Species Category
Sample Types:
Applications: Neutralization

Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines.
Authors: Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B
Clin. Immunol., 2006-06-16;120(2):220-31.
Species: Human
Sample Types: Blister Fluid, Cell Culture Supernates
Applications: ELISA Development, Neutralization

Circulating CD34+ progenitor cells modulate host angiogenesis and inflammation in vivo.
Authors: Popa ER, Harmsen MC, Tio RA, van der Strate BW, Brouwer LA, Schipper M, Koerts J, De Jongste MJ, Hazenberg A, Hendriks M, van Luyn MJ
J. Mol. Cell. Cardiol., 2006-06-14;41(1):86-96.
Species: Human
Sample Types: Whole Cells
Applications: ICC

PAPP-A and osteoprotegerin, together with interleukin-8 and RANTES, are elevated in the peritoneal fluid of women with endometriosis.
Authors: Bersinger NA, von Roten S, Wunder DM, Raio L, Dreher E, Mueller MD
Am. J. Obstet. Gynecol., 2006-04-25;195(1):103-8.
Species: Human
Sample Types: Peritoneal Fluid
Applications: ELISA Development

Proteinase-activated receptor2 agonists upregulate granulocyte colony-stimulating factor, IL-8, and VCAM-1 expression in human bronchial fibroblasts.
Authors: Ramachandran R, Morice AH, Compton SJ
Am. J. Respir. Cell Mol. Biol., 2006-02-23;35(1):133-41.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells.
Authors: Edwards MR, Johnson MW, Johnston SL
Am. J. Respir. Cell Mol. Biol., 2006-01-19;34(5):616-24.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Increased ENA-78 in the follicular fluid of patients with endometriosis.
Authors: Wunder DM, Mueller MD, Birkhauser MH, Bersinger NA
Acta Obstet Gynecol Scand, 2006-01-01;85(3):336-42.
Species: Human
Sample Types: Follicular Fluid
Applications: ELISA Development

IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
J. Immunol., 2005-11-01;175(9):6177-89.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Neutralization

Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis.
Authors: Ren Y, Lin CL, Li Z, Chen XY, Huang X, Lui V, Nicholls J, Lan HY, Tam PK
Histopathology, 2005-06-01;46(6):659-67.
Species: Human
Sample Types: Whole Cells
Applications: ICC

Interleukin-6 and interleukin-8 in cervical fluid in a population of Swedish women in preterm labor: relationship to microbial invasion of the amniotic fluid, intra-amniotic inflammation, and preterm delivery.
Authors: Holst RM, Mattsby-Baltzer I, Wennerholm UB, Hagberg H, Jacobsson B
Acta Obstet Gynecol Scand, 2005-06-01;84(6):551-7.
Species: Human
Sample Types: Amniotic Fluid
Applications: ELISA Development

The activation of IL-8 receptors in cultured guinea pig Muller glial cells is modified by signals from retinal pigment epithelium.
Authors: Malgorzata Goczalik I, Raap M, Weick M, Milenkovic I, Heidmann J, Enzmann V, Wiedemann P, Reichenbach A, Francke M
J. Neuroimmunol., 2005-04-01;161(1):49-60.
Species: Guinea Pig
Sample Types: Whole Cells
Applications: ICC

GCP-2/CXCL6 synergizes with other endothelial cell-derived chemokines in neutrophil mobilization and is associated with angiogenesis in gastrointestinal tumors.
Authors: Penninckx F, Ectors N
Exp. Cell Res., 2005-02-15;303(2):331-42.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis.
Authors: Phillips TM
Electrophoresis, 2004-06-01;25(10):1652-9.
Species: Human
Sample Types: Serum
Applications: Affinity Chromatography

17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells.
Authors: Bengtsson AK, Ryan EJ, Giordano D, Magaletti DM, Clark EA
Blood, 2004-05-13;104(5):1404-10.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
Authors: Copeland S, Siddiqui J, Remick D
J. Immunol. Methods, 2004-01-01;284(1):99-106.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Array Development

ELR+ CXC chemokines in human milk.
Authors: Maheshwari A, Christensen RD, Calhoun DA
Cytokine, 2003-11-07;24(3):91-102.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P

Interleukin-8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor-alpha and interleukin-1 beta.
Authors: Park JS, 107290, Kim YS, Jee YK, Myong NH, Lee KY
Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models, 2003-05-01;57(5):463-9.
Species: Human
Sample Types: Whole Tissue
Applications: IHC

Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells.
Authors: Hurst SM, McLoughlin RM, Monslow J, Owens S, Morgan L, Fuller GM, Topley N, Jones SA
J. Immunol., 2002-11-01;169(9):5244-51.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Expression of functional CCR and CXCR chemokine receptors in podocytes.
Authors: Huber TB, Reinhardt HC, Exner M, Burger JA, Kerjaschki D, Saleem MA, Pavenstadt H
J. Immunol., 2002-06-15;168(12):6244-52.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr

Metabolic replacement of kidney function in uremic animals with a bioartificial kidney containing human cells.
Authors: Humes HD, Fissell WH, Weitzel WF, Buffington DA, Westover AJ, MacKay SM, Gutierrez JM
Am. J. Kidney Dis., 2002-05-01;39(5):1078-87.
Species: Human
Sample Types: Whole Cells
Applications: ELISA Development

Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain.
Authors: Hirst SJ, Hallsworth MP, Peng Q
Am. J. Respir. Crit. Care Med., 2002-04-15;165(8):1161-71.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation.
Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA
Immunity, 2001-06-01;14(6):705-14.
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Chemoattractant factors in breast milk from allergic and nonallergic mothers.
Authors: Bottcher MF, Jenmalm MC, Bjorksten B, Garofalo RP
Pediatr. Res., 2000-05-01;47(5):592-7.
Species: Human
Sample Types: Serum
Applications: ELISA Development

Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment
Authors: Mirella Georgouli, Cecilia Herraiz, Eva Crosas-Molist, Bruce Fanshawe, Oscar Maiques, Anna Perdrix et al.
Cell

Autophagy-based unconventional secretion of HMGB1 in glioblastoma promotes chemosensitivity to temozolomide through macrophage M1-like polarization
Authors: Li Z, Fu WJ, Chen XQ et al.
Journal of experimental & clinical cancer research : CR

Expression of human papillomavirus type 16 E7 is sufficient to significantly increase expression of angiogenic factors but is not sufficient to induce endothelial cell migration
Authors: Joanna Walker, Lucy Clare Smiley, David Ingram, Ann Roman
Virology

Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway
Authors: X Sun, B Shi, H Zheng, L Min, J Yang, X Li, X Liao, W Huang, M Zhang, S Xu, Z Zhu, H Cui, X Liu
Cell Death Dis, 2018-02-15;9(3):260.

Interleukin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma
Authors: Dan Huang, Yan Ding, Ming Zhou, Brian I. Rini, David Petillo, Chao-Nan Qian et al.
Cancer Research

Endothelial P2Y2 receptor regulates LPS-induced neutrophil transendothelial migration in vitro
Authors: Filip Kukulski, Fethia Ben Ben Yebdri, Fariborz Bahrami, Michel Fausther, Alain Tremblay, Jean Sévigny
Molecular Immunology

Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization
Authors: Jie Ji, Swapna Upadhyay, Xiaomiao Xiong, Maria Malmlöf, Thomas Sandström, Per Gerde et al.
Particle and Fibre Toxicology

PHF11 expression and cellular distribution is regulated by the Toll-Like Receptor 3 Ligand Polyinosinic:Polycytidylic Acid in HaCaT keratinocytes
Authors: Pauline Muscat, Karessa Mercado, Kathryn Payne, Hardip Chahal, Graham Jones
BMC Immunology

Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production
Authors: Ravi Holani, Anshu Babbar, Graham A. D. Blyth, Fernando Lopes, Humberto Jijon, Derek M. McKay et al.
Gut Microbes

Schwann cells promote the migration and invasion of colorectal cancer cells via the activated NF-kappa B/IL-8 axis in the tumor microenvironment
Authors: Shuhai Chen, Mingyou Chen
Frontiers in Oncology

Human neutrophils depend on extrinsic factors produced by monocytes for their survival response to TLR4 stimulation
Authors: Shuvasree SenGupta, Madhavi J Rane, Silvia M Uriarte, Cassandra Woolley, Thomas C Mitchell
Innate Immunity

Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
Authors: Vinit Kumar, Laxminarasimha Donthireddy, Douglas Marvel, Thomas Condamine, Fang Wang, Sergio Lavilla-Alonso et al.
Cancer Cell

Mitochondrial DNA has a pro-inflammatory role in AMD
Authors: Bernard Dib, Haijiang Lin, Daniel E. Maidana, Bo Tian, John B. Miller, Peggy Bouzika et al.
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study
Authors: Michael Lichtenauer, Michael Mildner, Konrad Hoetzenecker, Matthias Zimmermann, Bruno Karl Podesser, Wolfgang Sipos et al.
Basic Research in Cardiology

IFNgamma induces JAK1/STAT1/p65 NFkappaB-dependent interleukin-8 expression in ovarian cancer cells, resulting in their increased migration
Authors: S Padmanabha, B Gaire, Y Zou, MM Uddin, D DeLeon, I Vancurova
The international journal of biochemistry & cell biology, 2021-10-06;141(0):106093.

Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients
Authors: Antonia Patsialou, Yarong Wang, Juan Lin, Kathleen Whitney, Sumanta Goswami, Paraic A Kenny et al.
Breast Cancer Research

N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM
Authors: G Kaufman, D Skrtic
Int J Mol Sci, 2020-10-03;21(19):.