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Human IL-11 R alpha (NP_001136256) VersaClone cDNA

Catalog #: RDC0857
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RDC0857
R&D Systems VersaClone cDNA Plasmids
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Human IL-11 R alpha (NP_001136256) VersaClone cDNA Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: IL-11 R alpha

IL-11 Ra (Interleukin-11 receptor alpha) is a widely expressed transmembrane protein that associates with gp130 to form a functional receptor complex for the cytokine IL-11. gp130 also functions as a subunit in the receptors for Cardiotrophin-1, CNTF, IL-6, IL-27, IL-31, LIF, and Oncostatin M. IL-11 Ra plays a role in female reproduction and the survival of oligodendrocytes and colonic epithelial cells. It enhances osteoclast differentiation and bone remodeling but inhibits adipocyte differentiation. Soluble IL-11 Ra confers IL-11 responsiveness to cells expressing gp130, while in cells expressing transmembrane IL-11 Ra and gp130, soluble IL-11 Ra acts as an IL-11 antagonist.

Long Name
Interleukin 11 Receptor alpha
Entrez Gene IDs
3590 (Human); 16157 (Mouse)
Alternate Names
AI314697; GP130; IL-11 R alpha; IL11R alpha; IL11RA; IL-11Ra; Il11ra2; NR1

Citation for Human IL-11 R alpha (NP_001136256) VersaClone cDNA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. The Interleukin-11/IL-11 Receptor Promotes Glioblastoma Survival and Invasion under Glucose-Starved Conditions through Enhanced Glutaminolysis
    Authors: SF Stuart, A Bezawork-G, Z Areeb, J Gomez, V Tsui, A Zulkifli, L Paradiso, J Jones, HPT Nguyen, TL Putoczki, PV Licciardi, G Kannouraki, AP Morokoff, AA Achuthan, RB Luwor
    International Journal of Molecular Sciences, 2023-02-08;24(4):.  2023-02-08

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